Schierling, Wilma and Matzner, Julia and Apfelbeck, Hanna and Grothues, Dirk and Oberhoffer-Fritz, Renate and Pfister, Karin (2022) Pulse Wave Velocity for Risk Stratification of Patients with Aortic Aneurysm. JOURNAL OF CLINICAL MEDICINE, 11 (14): 4026. ISSN , 2077-0383
Full text not available from this repository. (Request a copy)Abstract
Background: Patients with an aortic aneurysm are at high cardiovascular risk. Pulse wave velocity (PWV) is used as a parameter for risk stratification but may be affected by aortic disease (AoD). This study aimed to investigate the dependence of PWV on treated or untreated AoD and to identify modifiable factors of PWV. Methods: The measurement of PWV with the Mobil-O-Graph was performed fully automatically in a collective of 381 patients (75.6% male and 24.4% female). Of all patients, 53.8% had nonaortic atherosclerotic vascular disease (AVD), 28.9% had treated AoD, and 17.3% had untreated AoD. Results: There was a statistically significant effect of age (R-2 = 0.838) and current systolic blood pressure (SBP) on PWV (p(age corrected) < 0.05). After correction for age, no statistically significant difference was found between the PWV of men and women, patients with different body weights or degrees of chronic kidney disease, diabetics and nondiabetics, and smokers and nonsmokers. Comparison between patients with nonaortic AVD and treated or untreated AoD revealed no statistically significant differences (PWVnonaortic AVD 10.0 +/- 1.8 m/s, PWVtreated AoD 10.0 +/- 1.5 m/s, PWVuntreated AoD 9.8 +/- 1.6 m/s; p(age corrected) > 0.05). Conclusions: PWV determined with the Mobil-O-Graph correlated with age and current SBP. Neither aortic disease versus nonaortic AVD, its treatment, nor other cardiovascular risk factors had a significant effect on PWV. Successful blood pressure control is crucial to avoid high PWV and thus an increase in cardiovascular events.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ARTERIAL STIFFNESS; AUGMENTATION INDEX; REPAIR; VALIDATION; PRESSURE; abdominal aortic aneurysm (AAA); arterial stiffness; atherosclerosis; endovascular aneurysm repair (EVAR); Mobil-O-Graph; pulse wave velocity (PWV) |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie Medicine > Lehrstuhl für Kinder- und Jugendmedizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Feb 2024 13:19 |
| Last Modified: | 14 Feb 2024 13:19 |
| URI: | https://pred.uni-regensburg.de/id/eprint/57404 |
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