Kern, Anna and Kuhlmann, Pia H. and Matl, Stefan and Ege, Markus and Maison, Nicole and Eckert, Jana and von Both, Ulrich and Behrends, Uta and Anger, Melanie and Fruehwald, Michael C. and Gerstlauer, Michael and Woelfle, Joachim and Neubert, Antje and Melter, Michael and Liese, Johannes and Goettler, David and Sing, Andreas and Liebl, Bernhard and Huebner, Johannes and Klein, Christoph and COVID Kids Bavaria Consortium, (2022) Surveillance of Acute SARS-CoV-2 Infections in Elementary Schools and Daycare Facilities in Bavaria, Germany (09/2020-03/2021). FRONTIERS IN PEDIATRICS, 10: 888498. ISSN 2296-2360,
Full text not available from this repository. (Request a copy)Abstract
IntroductionHere we report our results of a multi-center, open cohort study ("COVID-Kids-Bavaria") investigating the distribution of acute SARS-CoV-2 infections among children and staff in 99 daycare facilities and 48 elementary schools in Bavaria, Germany. Materials and MethodsOverall, 2,568 children (1,337 school children, 1,231 preschool children) and 1,288 adults (466 teachers, 822 daycare staff) consented to participate in the study and were randomly tested in three consecutive phases (September/October 2020, November/December 2020, March 2021). In total, 7,062 throat swabs were analyzed for SARS-CoV-2 by commercial RT-PCR kits. ResultsIn phase I, only one daycare worker tested positive. In phase II, SARS-CoV-2 was detected in three daycare workers, two preschool children, and seven school children. In phase III, no sample tested positive. This corresponds to a positive test rate of 0.05% in phase I, 0.4% in phase II and 0% in phase III. Correlation of a positive PCR test result with the local-7-day incidence values showed a strong association of a 7-day-incidence of more than 100/100,000 as compared to <100/100,000 (OR = 10.3 [1.5-438], p < 0.005). After phase III, antibody testing was offered to 713 study participants in elementary schools. A seroprevalence rate of 7.7% (students) and 4.5% (teachers) was determined. DiscussionDuring the initial waves of the SARS-CoV-2 pandemic, the risk of a positive SARS-CoV-2 result correlated positively with the local 7-day incidence. Hence, the occurrence of SARS-CoV-2 infections were reflected in schools and daycare facilities. An increased risk of SARS-CoV-2 transmission in the setting of daycare and elementary schooling was unlikely.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | EXPOSURE RATE; TRANSMISSION; CHILDREN; SARS-CoV-2; surveillance; children; elementary school; preschool; PCR; seroprevalence |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Kinder- und Jugendmedizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 01 Feb 2024 13:12 |
| Last Modified: | 01 Feb 2024 13:12 |
| URI: | https://pred.uni-regensburg.de/id/eprint/58408 |
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