Feyrer, Antonia and Kerkel, Katharina and Mlcochova, Eva and Langguth, Berthold and Schecklmann, Martin (2025) No sex difference in the antidepressive effect of transcranial magnetic stimulation (TMS): results from a retrospective analysis of a large real-world sample. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY, 26 (4). pp. 170-178. ISSN 1562-2975, 1814-1412
Full text not available from this repository. (Request a copy)Abstract
ObjectivesThere is only limited knowledge about the impact of sex on the effectiveness of repetitive transcranial magnetic stimulation (rTMS) in depressive disorders. Here, we analysed a large real-world sample of depressive patients with respect to potential sex-specific effects of rTMS treatment.MethodsData of 984 patients (539 females/445 males) were analysed. Patients received various antidepressant TMS protocols, most of them 10Hz, 20 Hz, Theta burst or accelerated protocols over the left dorsolateral prefrontal cortex. Changes in Hamilton Depression Scale (HAMD) and Major Depression Inventory (MDI) scores as well as response and remission rates were compared between female and male patients.ResultsThere were no significant differences in any outcome between female and male patients. Response rates according to the HAMD-21 scores were 34.3% for females and 30.1% for males, according to the MDI 33.1% and 33.5% respectively. In an additional explorative analysis there was a tendency towards better outcome for females for the 20 Hz protocol.ConclusionsThe antidepressive effectiveness of rTMS does not differ between men and women.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | GENDER-DIFFERENCES; THETA BURST; DEPRESSION; RTMS; EPIDEMIOLOGY; SYMPTOMS; CORTEX; major depressive disorder; rTMS; neurostimulation; MDD; gender |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Psychiatrie und Psychotherapie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 09 Jun 2026 07:18 |
| Last Modified: | 09 Jun 2026 07:18 |
| URI: | https://pred.uni-regensburg.de/id/eprint/65933 |
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