Experts' attitudes towards 'targeted autopsies' using qualitative interviews in a medical network in Germany

Kaiser, Ulrich and Evert, Katja and Vehling-Kaiser, Ursula and Lüke, Florian and Herr, Wolfgang and Rechenmacher, Michael (2025) Experts' attitudes towards 'targeted autopsies' using qualitative interviews in a medical network in Germany. BMJ OPEN, 15 (10): e098127. ISSN 2044-6055,

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Abstract

Objectives The behaviour of tumour metastases and the different responses to therapies are still not fully understood. The project 'targeted autopsies' of the Universities of Regensburg and Erlangen aimed to further uncover the metastatic behaviour of malignant tumours by scientifically processing different tumour samples. To initiate such a programme, the concerns of all possible stakeholders must be analysed so that the programme can be set up accordingly and the highest possible level of approval can be achieved.Design This study investigated the basic attitude toward a targeted autopsy programme for patients with tumours and possible criteria for such a programme using qualitative interviews. Focus group discussions were held to explore the opinions and views regarding ethical aspects of various professional groups (experts) involved in this project. An interview guideline was prepared beforehand by the supervising project group. Semistructured interviews were conducted, transcribed and analysed through qualitative content analysis according to Mayring.Setting University of Regensburg, Germany and cooperating medical partners.Results Altogether, 15 experts were interviewed. The experts described the project as interesting and feasible. They assumed a sufficient participation rate in this autopsy programme from the population; however, they recommend giving importance to providing sufficient and professional education to all persons involved. Preserving the dignity of the donor and providing appropriate care for relatives is of great importance. Good organisation is considered imperative for the success of the project.Conclusion Generally, experts favour the implementation of a targeted autopsy programme. However, some hurdles must be overcome. Challenges similar to those in general or rapid autopsy and organ donation programmes exist, such as donor recruitment, staffing shortages and financial constraints. People involved must be well informed before the project.

Item Type: Article
Uncontrolled Keywords: RAPID AUTOPSY; PATHOLOGISTS; CONSENT; Decision Making; Medicine; Adult pathology
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Medicine > Lehrstuhl für Pathologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 09 Jun 2026 08:36
Last Modified: 09 Jun 2026 08:36
URI: https://pred.uni-regensburg.de/id/eprint/65939

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