Heuer, Henrik and Song, Zhiyang and Hegner, Philipp and Truong, Andre and Wiesner, Sigrid and Terrazas, Armando and Larisch, Christopher and Aigner, Hans-Christoph and Floerchinger, Bernhard and Schmid, Christof and Li, Jing (2026) Delayed Sternal Closure in Heart Surgery: Outcomes and Quality of Life. THORACIC AND CARDIOVASCULAR SURGEON, 74 (01). pp. 28-38. ISSN 0171-6425, 1439-1902
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Background Delayed sternal closure (DSC) is a well-established strategy used to manage patients with hemodynamic instability and perioperative coagulopathy following cardiac surgery. The study aims to present our 15-year surgical experiences with DSC. Methods Between 2007 and 2022, DSC was performed in 227 out of 14,210 patients (1.7%) who underwent cardiac surgery at our institution. Perioperative data, outcomes, and long-term survival were analyzed. Quality of life (QoL) was assessed utilizing the EuroQol-5D-5L questionnaire. Results Indications for DSC included low cardiac output syndrome (LCOS) (44.1%) and coagulopathy during the index procedure (32.2%), as well as postoperative tamponade (22.9%). In coronary artery bypass grafting, LCOS was the primary indication for DSC (72.7%), whereas in acute type A aortic dissection, coagulopathy was the leading indication (70.6%). For other procedures, DSC indications were more evenly distributed. The overall 30-day survival was 57.5%, with survival rates of 43.3% for LCOS, 72.0% for coagulopathy, and 65.4% for tamponade. Multivariate logistic regression identified body mass index, postoperative renal replacement therapy, aggravated heart failure, and intraoperative packed red blood cell transfusion as negatively associated with 30-day survival. The mean follow-up period was 6.58 +/- 3.19 years. Younger patients and DSC patients upon bleeding related indications reported higher QoL in comparison to older patients and patients with LCOS. Longer follow-up interval correlated with higher QoL. Conclusion The study emphasizes the significant impact of LCOS on outcomes in patients undergoing DSC. We provide QoL data demonstrating good rehabilitation potential upon survival of the acute phase.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CARDIAC-SURGERY; THERAPY; SUPPORT; surgery; complications; outcomes (includes mortality; morbidity); heart failure; sternum; quality of life; postoperative care |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Anästhesiologie Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 12 Aug 2026 05:33 |
| Last Modified: | 12 Aug 2026 05:33 |
| URI: | https://pred.uni-regensburg.de/id/eprint/66070 |
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