Chen, Junyi and Wang, Huan and Wang, Jinlin and Zheng, Xixi and Qu, Wantong and Fang, Huijian and Wang, Shuang and He, Le and Hao, Shuang and Dresselhaus, Thomas (2025) Fertilization-induced synergid cell death by RALF12-triggered ROS production and ethylene signaling. NATURE COMMUNICATIONS, 16 (1): 3059. ISSN 2041-1723
Full text not available from this repository. (Request a copy)Abstract
Fertilization-dependent elimination of the persistent synergid cell is essential to block supernumerary pollen tubes and thus to avoid polyspermy in flowering plants. Little is known about the molecular mechanisms ensuring timely induction and execution of synergid cell death. We analyzed manually isolated maize synergid cells along their degeneration and show that they are gland cells expressing batteries of genes encoding small secreted proteins under control of the MYB98 transcription factor. This network is down-regulated after fertilization, while genes involved in reactive oxygen species (ROS) production, ethylene biosynthesis and response, senescence, and oxidative stress regulation are induced before synergid elimination and its ultimate fusion with the endosperm. We further show that the fertilization-induced RALF12 peptide specifically triggers mitochondrial ROS and apoptosis, while ethylene promotes synergid degeneration. In conclusion, this study sheds light on developmental programmed cell death (dPCD) in plants and provides a unique resource to discover unknown PCD regulators.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | OXIDATIVE STRESS; ARABIDOPSIS; MECHANISM; CALCIUM; DEGENERATION; ELIMINATION; ACTIVATION; PEPTIDES; PATHWAY; BLOCK |
| Subjects: | 500 Science > 570 Life sciences 500 Science > 580 Botanical sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Pflanzenwissenschaften |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 28 Jul 2026 06:30 |
| Last Modified: | 28 Jul 2026 06:30 |
| URI: | https://pred.uni-regensburg.de/id/eprint/66764 |
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