Photochemistry and homogeneous acid catalysis: A visible light route to β-amino alcohols

Bernardoni, Beatrice and Di Terlizzi, Lorenzo and Fagnoni, Maurizio and Bousquet, Till and Protti, Stefano (2026) Photochemistry and homogeneous acid catalysis: A visible light route to β-amino alcohols. APPLIED CATALYSIS A-GENERAL, 709: 120610. ISSN 0926-860X, 1873-3875

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Abstract

The beta-amino alcohol moiety is commonly present in either natural and labmade bioactive compounds with multifaceted applications, spanning pharmaceutics, material sciences and asymmetric synthesis. Among the different strategies adopted to achieve this target, the aminolysis of epoxides in the presence of either Bronsted or Lewis acids is mainly followed. We present herein a versatile, visible light promoted protocol for the preparation of beta-amino alcohols from epoxides, by exploiting the peculiar reactivity of photoactivatable arylazo sulfones as Photo Acid Generators (PAGs).

Item Type: Article
Uncontrolled Keywords: SULFATED ZIRCONIA; AROMATIC-AMINES; EPOXIDES; EFFICIENT; DERIVATIVES; WATER; HYDROGENATION; PYRROLIDINES; MICROWAVE; OXIRANES; Acid Catalysis; Arylazo Sulfones; Visible Light; Aminolysis; Photo Acid Generators; (PAGs)
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Depositing User: Dr. Gernot Deinzer
Date Deposited: 15 Apr 2026 06:56
Last Modified: 15 Apr 2026 06:56
URI: https://pred.uni-regensburg.de/id/eprint/67295

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