Ortmann, Olaf and Roth, Rebecca and Klages, Birgit and Kowalski, Christoph and Bruns, Johannes and Wimberger, Pauline and Sehouli, Jalid and Beckmann, Matthias W. and Schuler-Toprak, Susanne (2025) Correlation of surgical volume in gynecological cancer centers with the quality of ovarian cancer care. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 151 (8): 239. ISSN 0171-5216, 1432-1335
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Purpose Surgical volume in ovarian cancer treatment has been discussed to influence survival. Completeness of staging in early and macroscopic complete resection in advanced ovarian cancer are indicators of treatment quality and surrogate parameters for outcome. This study examines their association with case volume in certified gynecological cancer centers. Methods Certification audit data from ovarian cancer cases treated in 193 gynecological cancer centers certified by the German Cancer Society between 2020 and 2022 were analyzed. In our study 3,881 patients with FIGO stage I-IIIA and 7,219 patients with FIGO stage IIB-IV ovarian cancer were included. Case volume thresholds of 10, 15, 20 and 25 annual cases per hospital were explored for both quality indicators. Results Higher-volume centers consistently performed complete surgical staging in FIGO stage I-IIIA ovarian cancer patients more frequently. For example, centers treating < 15 cases annually had a lower likelihood of complete staging (OR 0.82; 95% CI 0.69-0.98; p = 0.031). Macroscopic complete resection was achieved in 72.32-75.64% of FIGO stage IIB-IV ovarian cancer cases across all four thresholds. High-volume centers performed macroscopic complete resection about 2 percentage points more often. Conclusion These data indicate that case volume of cancer centers is not necessarily an indicator for quality of treatment. Since certification audit data does not account for primary surgery or neoadjuvant chemotherapy, the inherent bias caused by differences in resection rates between these two treatment strategies must be acknowledged.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SURVIVAL; OUTCOMES; IMPACT; PATTERNS; PROGRAM; SURGERY; Ovarian cancer; Surgical volume; Complete surgical staging; Macroscopic complete resection |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Frauenheilkunde und Geburtshilfe (Schwerpunkt Frauenheilkunde) Medicine > Lehrstuhl für Frauenheilkunde und Geburtshilfe (Schwerpunkt Geburtshilfe) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 28 Jul 2026 09:53 |
| Last Modified: | 28 Jul 2026 09:59 |
| URI: | https://pred.uni-regensburg.de/id/eprint/67296 |
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