Middle Meningeal Artery Embolization for the Treatment of Chronic Subdural Hematomas-a German Nationwide Multi-center Study On 718 Embolizations

Vollherbst, Dominik F. and Berlis, Ansgar and Zaki, Mahmoud and Maurer, Christoph and Onyinzo, Christina and Keil, Fee C. and Mann, Leonard and Arendt, Christophe T. and Hartmann, Marius and Reissberg, Steffen and Rutschke, Corinna and Kallenberg, Kai and Grau, Stefan and Durutya, Alexandru and Liebert, Adrian and Voit-Hoehne, Heinz L. and Holtmannspoetter, Markus and Herweh, Christian and Chapot, Rene and Elsharkawy, Mohamed and Meila, Dan and Greling, Bjoern and Boxberg, Frederik and Grieb, Dominik and Deuschl, Cornelius and Ahmadipour, Yahya and Boeckh-Behrens, Tobias and Bodden, Jannis and Lukas, Carsten and Kaemmerer, Felix and Behme, Daniel and Diamandis, Elie and Siebert, Eberhard and Meddeb, Aymen and Kreiser, Kornelia and Heinz, Sabine and Meckel, Stephan and Berzeg-Kolck, Semin and Fiehler, Jens and Bechstein, Matthias and Kaschner, Marius G. and Darvishi, Keihan and Leukert, Laura S. and Brockmann, Marc A. and Mayer, Thomas E. and Buhk, Jan-Hendrik and Weyland, Charlotte S. and Goertz, Lukas and Kabbasch, Christoph and Weber, Werner and Wendl, Christina and Struffert, Tobias and Dyzmann, Christian and Gerber, Johannes C. and Bendszus, Martin and Moehlenbruch, Markus A. (2025) Middle Meningeal Artery Embolization for the Treatment of Chronic Subdural Hematomas-a German Nationwide Multi-center Study On 718 Embolizations. SPRINGER HEIDELBERG, HEIDELBERG.

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Abstract

Background Embolization of the middle meningeal artery (EMMA) is a promising novel technique for the treatment of patients with chronic subdural hematomas (cSDH). Methods After a nationwide query in Germany, patients with cSDH, treated with EMMA were retrospectively analyzed. Patient and cSDH characteristics, procedural parameters, complications, and rates of treatment failure (TF; residual cSDH > 10 mm, cSDH progression or requirement of rescue surgery) were investigated. TF rates were compared between first-time treatments and treatments of recurrent cSDH, patients receiving embolization and surgery and those being embolized only, different types of embolic agents (particles vs. liquid agents) and between patients with and without antithrombotic medication. Results 718 EMMAs (420 unilateral, 149 bilateral) were performed in 569 patients in 30 German neurovascular centers. 57.1% were first-time treatments and 42.9% were treatments of recurrent cSDHs. The most frequently used embolic agents were particles (56.2%), followed by copolymer-based liquid embolic agents (19.6%). The rate of symptomatic procedure-related complications was 2.5%. After a mean follow-up of 6.5 months, TF was observed in 16.2% across all treatments and was more frequent after the treatment of recurrent cSDHs (19.8% vs. 13.5%, p = 0.045) and in patients taking antithrombotic drugs (17.7% vs. 11.5%; p = 0.044). TF was not significantly different regarding the type of embolic agent or additional surgery. Conclusions In this nationwide multi-center study, EMMA was associated with favorable clinical outcomes and a low complication rate, supporting the results of recently published randomized controlled trials. TF was more frequent in recurrent cSDH treatments and in patients taking antithrombotic drugs.

Item Type: Other
Uncontrolled Keywords: MANAGEMENT; Middle meningeal artery; Embolization; Chronic subdural hematoma; Chronic subdural hemorrhage
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Röntgendiagnostik
Medicine > Zentrum für Neuroradiologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 29 Sep 2026 10:25
Last Modified: 29 Sep 2026 10:25
URI: https://pred.uni-regensburg.de/id/eprint/67658

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