Kefleyesus, Amaniel and Bakrin, Naoual and Kepenekian, Vahan and Gerbaud-Coulas, Chloe and Li, Anne and Vassal, Olivia and Eveno, Clarisse and Sgarbura, Olivia and Nelson, Gregg and Bouchard-Fortier, Antoine and Mack, Lloyd and Rivard, Justin and Fagotti, Anna and Kusamura, Shigeki and Robella, Manuela and Piso, Pompiliu and Acs, Miklos and Arias, Fernando and Rau, Beate and Lambert, Laura A. and Wadhwa, Anupama and Polanco, Patricio and Somashekhar, S. P. and Teixeira-Farinha, Hugo and Alyami, Mohammad and Glehen, Olivier and Hubner, Martin (2025) Enhanced recovery for cytoreductive surgery and hyperthermic intraperitoneal Chemotherapy: An international survey to assess acceptance and feasibility. EJSO, 51 (9): 110150. ISSN 0748-7983, 1532-2157
Full text not available from this repository.Abstract
Background: Enhanced Recovery After Surgery (ERAS) protocols have markedly improved outcomes after colorectal and other major surgery, suggesting benefits also for complex surgeries like Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC). This study investigates the adoption and acceptance of the recent ERAS recommendations for CRS-HIPEC within expert centers. Methods: Clinicians from 16 expert centers across 9 countries were invited to answer an online survey inquiring about current clinical practice. Adoption of the 72 ERAS items from the recent dedicated guidelines were evaluated using a Likert-type scale with focus on preoperative, perioperative, and postoperative phases. Results: Overall, 27 clinicians (11 female, 21 surgeons, 2 gynecologists and 4 anesthesiologists/intensivists) participated, with high adoption of ERAS protocols at baseline (67 %). More than half of the guideline items (54 %) were widely adopted. However, despite nearly 18 % intending to change their practices, there remains substantial resistance to further adoption, such as for measures like alcohol cessation programs, mechanical bowel preparation, and oral antibiotic decontamination. Barriers identified include resource limitations(20 %), perceived irrelevance (17 %) for specific patient groups, unclear benefits (59 %), and restrictive policies (5 %). Conclusion: The study shows that most ERAS principles are routinely implemented in CRS-HIPEC surgeries, despite significant challenges with specific components and complex processes. Future research will focus on generating additional evidence and streamlining ERAS guidelines to prioritize essential elements.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ; Enhanced recovery after surgery (ERAS); Cytoreductive surgery (CRS); Hyperthermic intraperitoneal chemotherapy (HIPEC); Perioperative care; Survey |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 17 Apr 2026 11:13 |
| Last Modified: | 17 Apr 2026 11:13 |
| URI: | https://pred.uni-regensburg.de/id/eprint/67690 |
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