Baum, Jonathan Hans Josef and Dorre, Achim and Boender, Tamara Sonia and Heldt, Katharina and Wilking, Hendrik and Drynda, Susanne and Erdmann, Bernadett and Grashey, Rupert and Grupp, Caroline and Habbinga, Kirsten and Hamelmann, Eckard and Heining, Amrei and Hoger-Schmidt, Heike and Kill, Clemens and Reichert, Friedrich and Risse, Joachim and Schilling, Tobias and Schranz, Madlen and Baacke, Markus and Bauer, Jaqueline and Bernhard, Michael and Bienzeisler, Jonas and Blaschke, Sabine and Brokmann, Jorg and Burst, Volker and Busch, Hans-Jorg and Dormann, Harald and Duesberg, Christoph and Ehrentreich, Saskia and Gries, Andre and Handl, Thomas and Handmann, Eric and Hans, Felix and Hanses, Frank and Henke, Thomas and Klein, Matthias and Hofmann, Tobias and Karg, Marina and Kleinekorth, Jan and Kombeiz, Alexander and Kumle, Bernhard and Kumpers, Philipp and Lewejohann, Christoph and Dinse-Lambracht, Alexander and Lucas, Benjamin and Mach, Carsten and Majeed, Raphael W. and Neubauer, Jurgen and Otto, Ronny and Peschel, Thomas and Pfeufer, Norbert and Rohrig, Rainer and Schirrmeister, Wiebke and Schunk, Domagoj and Stahl, Wolfgang and Stefani, Hartmut and Triefenbach, Lucas and Uirich, Bernd and Walcher, Felix and Wehler, Markus and Wenderoth, Hardy and Wolfrum, Sebastian and Wrede, Christian and Zimmermann, Markus (2025) Establishing and validating syndromic surveillance of gastrointestinal infections using routine emergency department data, Germany, 2019-2023. SCIENTIFIC REPORTS, 15 (1): 38281. ISSN 2045-2322,
Full text not available from this repository. (Request a copy)Abstract
Gastrointestinal infections in Germany account for 24.5 million outpatient visits annually. To enhance outbreak detection and trend monitoring, we developed and validated a syndrome definition for syndromic surveillance of gastrointestinal infections in emergency departments. We selected presenting complaints (Canadian Emergency Department Information System) and diagnoses (ICD-10) to develop the syndrome definition. Validation involved cross-correlation analysis of syndromic and laboratory-based surveillance trends (norovirus-gastroenteritis, rotavirus-gastroenteritis, campylobacteriosis and salmonellosis notifications). We included emergency departments from the German AKTIN registry with continuous data transmission (01/2019-06/2023). Our novel syndrome definition combined complaints (diarrhoea, vomiting, nausea) and diagnoses (intestinal infectious diseases). Across 864,353 visits in 7 emergency departments, 2.1% (n = 18,158) were gastrointestinal infection cases. Of those, 57% (n = 10,424) were female; 23% were aged 0-19 years (n = 4108); and 23% 20-39 years (n = 4116). Trends were similar between surveillance systems. Cross-correlation was 0.73 (95%-confidence interval 0.61-0.85; p < 0.001) at lag - 1, indicating a 1-week relative reporting delay of laboratory-based surveillance. Coherent trends and significant cross-correlation validated our syndrome definition. This novel automated syndromic surveillance complements laboratory-based surveillance while offering improved timeliness and reduced workload. Therefore, it was implemented in Germany's national routine surveillance of emergency departments.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ; Emergency service, hospital; Emergency department; Public health surveillance; Syndromic surveillance; Sentinel surveillance; Gastrointestinal infection; Gastrointestinal diseases; Gastroenteritis |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin Medicine > Abteilung für Krankenhaushygiene und Infektiologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 24 Mar 2026 05:56 |
| Last Modified: | 24 Mar 2026 05:56 |
| URI: | https://pred.uni-regensburg.de/id/eprint/68088 |
Actions (login required)
 |
View Item |
