Technical recommendations for analyzing oxylipins by liquid chromatography-mass spectrometry

Schebb, Nils Helge and Kampschulte, Nadja and Hagn, Gerhard and Plitzko, Kathrin and Meckelmann, Sven W. and Ghosh, Soumita and Joshi, Robin and Kuligowski, Julia and Vuckovic, Dajana and Botana, Marina T. and Sanchez-Illana, Angel and Zandkarimi, Fereshteh and Das, Aditi and Yang, Jun and Schmidt, Louis and Checa, Antonio and Roche, Helen M. and Armando, Aaron M. and Edin, Matthew L. and Lih, Fred B. and Aristizabal-Henao, Juan J. and Miyamoto, Sayuri and Giuffrida, Francesca and Moussaieff, Arieh and Domingues, Rosario and Rothe, Michael and Hinz, Christine and Das, Ujjalkumar Subhash and Rund, Katharina M. and Taha, Ameer Y. and Hofstetter, Robert K. and Werner, Markus and Werz, Oliver and Kahnt, Astrid S. and Bertrand-Michel, Justine and Le Faouder, Pauline and Gurke, Robert and Thomas, Dominique and Torta, Federico and Milic, Ivana and Dias, Irundika H. K. and Spickett, Corinne M. and Biagini, Denise and Lomonaco, Tommaso and Idborg, Helena and Liu, Jun-Yan and Fedorova, Maria and Ford, David A. and Barden, Anne and Mori, Trevor A. and Kennedy, Paul D. and Maxey, Kirk and Ivanisevic, Julijana and Gallart-Ayala, Hector and Gladine, Cecile and Wenk, Markus and Galano, Jean-Marie and Durand, Thierry and Stark, Ken D. and Barbas, Coral and Garscha, Ulrike and Gelhaus, Stacy L. and Ceglarek, Uta and Flamand, Nicolas and Griffin, Julian L. and Ahrends, Robert and Arita, Makoto and Zeldin, Darryl C. and Schopfer, Francisco J. and Quehenberger, Oswald and Julian, Randall and Nicolaou, Anna and Blair, Ian A. and Murphy, Michael P. and Hammock, Bruce D. and Freeman, Bruce and Liebisch, Gerhard and Serhan, Charles N. and Koefeler, Harald C. and Jakobsson, Per-Johan and Steinhilber, Dieter and Gelb, Michael H. and Holcapek, Michal and Andrew, Ruth and Giera, Martin and Fitzgerald, Garret A. and Murphy, Robert C. and Newman, John W. and Dennis, Edward A. and Ekroos, Kim and Milne, Ginger L. and Gijon, Miguel A. and Vesper, Hubert W. and Wheelock, Craig E. and O'Donnell, Valerie B. (2025) Technical recommendations for analyzing oxylipins by liquid chromatography-mass spectrometry. SCIENCE SIGNALING, 18 (887): eadw1245. ISSN 1945-0877, 1937-9145

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Abstract

Several oxylipins are potent lipid mediators that regulate diverse aspects of health and disease and whose quantitative analysis by liquid chromatography-mass spectrometry (LC-MS) presents substantial technical challenges. As members of the lipidomics community, we developed technical recommendations to ensure best practices when quantifying oxylipins by LC-MS.

Item Type: Article
Uncontrolled Keywords: PROSTAGLANDIN
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin
Depositing User: Dr. Gernot Deinzer
Date Deposited: 11 Aug 2026 06:43
Last Modified: 11 Aug 2026 06:43
URI: https://pred.uni-regensburg.de/id/eprint/68110

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