Items where Author is "Beckers, Thomas"

Article

Beckers, Thomas and Mahboobi, Siavosh and Sellmer, Andreas and Winkler, Matthias and Eichhorn, Emerich and Pongratz, Herwig and Maier, Thomas and Ciossek, Thomas and Baer, Thomas and Kelter, Gerhard and Fiebig, Heinz-Herbert and Schmidt, Mathias (2012) Chimerically designed HDAC- and tyrosine kinase inhibitors. A series of erlotinib hybrids as dual-selective inhibitors of EGFR, HER2 and histone deacetylases. MEDCHEMCOMM, 3 (7). pp. 829-835. ISSN 2040-2503

Beckers, Thomas and Sellmer, Andreas and Eichhorn, Emerich and Pongratz, Herwig and Schaechtele, Christoph and Totzke, Frank and Kelter, Gerhard and Krumbach, Rebekka and Fiebig, Heinz-Herbert and Boehmer, Frank-D. and Mahboobi, Siavosh (2012) Novel inhibitors of epidermal growth factor receptor: (4-(Arylamino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)(1H-indol-2-yl)methanones and (1H-indol-2-yl)(4-(phenylamino)thieno[2,3-d]pyrimidin-6-yl)methanones. BIOORGANIC & MEDICINAL CHEMISTRY, 20 (1). pp. 125-136. ISSN 0968-0896

Uecker, Andrea and Sicker, Marit and Beckers, Thomas and Mahboobi, Siavosh and Hagerstrand, Daniel and Ostman, Arne and Boehmer, Frank-D. (2010) Chimeric tyrosine kinase-HDAC inhibitors as antiproliferative agents. ANTI-CANCER DRUGS, 21 (8). pp. 759-765. ISSN 0959-4973

Mahboobi, Siavosh and Sellmer, Andreas and Winkler, Matthias and Eichhorn, Emerich and Pongratz, Herwig and Ciossek, Thomas and Baer, Thomas and Maier, Thomas and Beckers, Thomas (2010) Novel Chimeric Histone Deacetylase Inhibitors: A Series of Lapatinib Hybrides as Potent Inhibitors of Epidermal Growth Factor Receptor (EGFR), Human Epidermal Growth Factor Receptor 2 (HER2), and Histone Deacetylase Activity. JOURNAL OF MEDICINAL CHEMISTRY, 53 (24). pp. 8546-8555. ISSN 0022-2623

Mahboobi, Siavosh and Dove, Stefan and Sellmer, Andreas and Winkler, Matthias and Eichhorn, Emerich and Pongratz, Herwig and Ciossek, Thomas and Baer, Thomas and Maier, Thomas and Beckers, Thomas (2009) Design of Chimeric Histone Deacetylase- and Tyrosine Kinase-Inhibitors: A Series of Imatinib Hybrides as Potent Inhibitors of Wild-Type and Mutant BCR-ABL, PDGF-R beta, and Histone Deacetylases. JOURNAL OF MEDICINAL CHEMISTRY, 52 (8). pp. 2265-2279. ISSN 0022-2623, 1520-4804

Mahboobi, Siavosh and Sellmer, Andreas and Hoecher, Heymo and Garhammer, Christian and Pongratz, Herwig and Maier, Thomas and Ciossek, Thomas and Beckers, Thomas (2007) 2-aroylindoles and 2-aroylbenzofurans with N-hydroxyacrylamide substructures as a novel series of rationally designed histone deacetylase inhibitors. JOURNAL OF MEDICINAL CHEMISTRY, 50 (18). pp. 4405-4418. ISSN 0022-2623, 1520-4804

Mahboobi, Siavosh and Sellmer, Andreas and Eichhorn, Emmerich and Beckers, Thomas and Fiebig, Heinz-Herbert and Kelter, Gerhard (2005) Synthesis and cytotoxic activity of 2-acyl-1H-indole-4,7-diones on human cancer cell lines. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 40 (1). pp. 85-92. ISSN 0223-5234, 1768-3254

Beckers, Thomas and Mahboobi, Siavosh (2003) Natural, semisynthetic and synthetic microtubule inhibitors for cancer therapy. DRUGS OF THE FUTURE, 28 (8). pp. 767-785. ISSN 0377-8282

Beckers, Thomas and Reissmann, Thomas and Schmidt, Mathias and Burger, Angelika M. and Fiebig, Heinz H. and Vanhoefer, Udo and Pongratz, Herwig and Hufsky, Harald and Hockemeyer, Jörg and Frieser, Markus and Mahboobi, Siavosh (2002) 2-aroylindoles, a novel class of potent, orally active small molecule tubulin inhibitors. CANCER RESEARCH, 62 (11). pp. 3113-3119. ISSN 0008-5472, 1538-7445

Mahboobi, Siavosh and Teller, Steffen and Pongratz, Herwig and Hufsky, Harald and Sellmer, Andreas and Botzki, Alexander and Uecker, Andrea and Beckers, Thomas and Baasner, Silke and Schaechtele, Christoph and Ueberall, Florian and Kassack, Matthias U. and Dove, Stefan and Boehmer, Frank-D. (2002) Bis(1H-2-indolyl)methanones as a novel class of inhibitors of the platelet-derived growth factor receptor kinase. JOURNAL OF MEDICINAL CHEMISTRY, 45 (5). pp. 1002-1018. ISSN 0022-2623, 1520-4804

Mahboobi, Siavosh and Pongratz, Herwig and Hufsky, Harald and Hockemeyer, Jörg and Frieser, Markus and Lyssenko, Alexei and Paper, Dietrich H. and Buergermeister, Jutta and Boehmer, Frank-D. and Fiebig, Heinz-Herbert and Burger, Angelika M. and Baasner, Silke and Beckers, Thomas (2001) Synthetic 2-aroylindole derivatives as a new class of potent tubulin-inhibitory, antimitotic agents. JOURNAL OF MEDICINAL CHEMISTRY, 44 (26). pp. 4535-4553. ISSN 0022-2623

Teller, Steffen and Eluwa, Stella and Koller, Markus and Uecker, Andrea and Beckers, Thomas and Baasner, Silke and Boehmer, Frank-D. and Mahboobi, Siavosh (2000) Pyrrolo[3,4-c]-beta-carboline-diones as a novel class of inhibitors of the platelet-derived growth factor receptor kinase. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 35 (4). pp. 413-427. ISSN 0223-5234