Items where Author is "Bernhardt, Guenther"

Article

Antoni, Frauke and Bernhardt, Guenther (2021) Derivatives of nitrogen mustard anticancer agents with improved cytotoxicity. ARCHIV DER PHARMAZIE, 354 (4): e2000366. ISSN 0365-6233, 1521-4184

Seibel-Ehlert, Ulla and Plank, Nicole and Inoue, Asuka and Bernhardt, Guenther and Strasser, Andrea (2021) Label-Free Investigations on the G Protein Dependent Signaling Pathways of Histamine Receptors. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22 (18): 9739. ISSN 1422-0067

Antoni, Frauke and Wifling, David and Bernhardt, Guenther (2021) Water-soluble inhibitors of ABCG2 (BCRP) - A fragment-based and computational approach. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 210: 112958. ISSN 0223-5234, 1768-3254

Spinnler, Katrin and von Kruechten, Lara and Konieczny, Adam and Schindler, Lisa and Bernhardt, Guenther and Keller, Max (2020) An Alkyne-functionalized Arginine for Solid-Phase Synthesis Enabling "Bioorthogonal" Peptide Conjugation. ACS MEDICINAL CHEMISTRY LETTERS, 11 (3). pp. 334-339. ISSN 1948-5875

Buschmann, Jonas and Seiler, Theresa and Bernhardt, Guenther and Keller, Max and Wifling, David (2020) Argininamide-type neuropeptide Y Y-1 receptor antagonists: the nature of N-omega-carbamoyl substituents determines Y1R binding mode and affinity. RSC MEDICINAL CHEMISTRY, 11 (2). pp. 274-282. ISSN 2632-8682

Keller, Max and Mahuroof, Shahani A. and Yee, Vivyanne Hong and Carpenter, Jessica and Schindler, Lisa and Littmann, Timo and Pegoli, Andrea and Huebner, Harald and Bernhardt, Guenther and Gmeiner, Peter and Holliday, Nicholas D. (2020) Fluorescence Labeling of Neurotensin(8-13) via Arginine Residues Gives Molecular Tools with High Receptor Affinity. ACS MEDICINAL CHEMISTRY LETTERS, 11 (1). pp. 16-22. ISSN 1948-5875

Biselli, Sabrina and Alencastre, Ines and Tropmann, Katharina and Erdmann, Daniela and Chen, Mengya and Littmann, Timo and Maia, Andre F. and Gomez-Lazaro, Maria and Tanaka, Miho and Ozawa, Takeaki and Keller, Max and Lamghari, Meriem and Buschauer, Armin and Bernhardt, Guenther (2020) Fluorescent H-2 Receptor Squaramide-Type Antagonists: Synthesis, Characterization, and Applications. ACS MEDICINAL CHEMISTRY LETTERS, 11 (8). pp. 1521-1528. ISSN 1948-5875

Konieczny, Adam and Braun, Diana and Wifling, David and Bernhardt, Guenther and Keller, Max (2020) Oligopeptides as Neuropeptide Y Y-4 Receptor Ligands: Identification of a High-Affinity Tetrapeptide Agonist and a Hexapeptide Antagonist. JOURNAL OF MEDICINAL CHEMISTRY, 63 (15). pp. 8198-8215. ISSN 0022-2623, 1520-4804

She, Xueke and Pegoli, Andrea and Gruber, Corinna G. and Wifling, David and Carpenter, Jessica and Huebner, Harald and Chen, Mengya and Wan, Jianfei and Bernhardt, Guenther and Gmeiner, Peter and Holliday, Nicholas D. and Keller, Max (2020) Red-Emitting Dibenzodiazepinone Derivatives as Fluorescent Dualsteric Probes for the Muscarinic Acetylcholine M-2 Receptor. JOURNAL OF MEDICINAL CHEMISTRY, 63 (8). pp. 4133-4154. ISSN 0022-2623, 1520-4804

Forster, Lisa and Graetz, Lukas and Moennich, Denise and Bernhardt, Guenther and Pockes, Steffen (2020) A Split Luciferase Complementation Assay for the Quantification of beta-Arrestin2 Recruitment to Dopamine D-2-Like Receptors. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21 (17): 6103. ISSN 1422-0067

Stolwijk, Judith A. and Mildner, Anne-Kathrin and Kade, Christian and Skiba, Michael and Bernhardt, Guenther and Buschauer, Armin and Huebner, Harald and Gmeiner, Peter and Wegener, Joachim (2020) Stepwise Dosing Protocol for Increased Throughput in Label-Free Impedance-Based GPCR Assays. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (156): e60686. ISSN 1940-087X

Antoni, Frauke and Bause, Manuel and Scholler, Matthias and Bauer, Stefanie and Stark, Simone A. and Jackson, Scott M. and Manolaridis, Ioannis and Locher, Kaspar P. and Koenig, Burkhard and Buschauer, Armin and Bernhardt, Guenther (2020) Tariquidar-related triazoles as potent, selective and stable inhibitors of ABCG2 (BCRP). EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 191: 112133. ISSN 0223-5234, 1768-3254

Bartole, Edith and Graetz, Lukas and Littmann, Timo and Wifling, David and Seibel, Ulla and Buschauer, Armin and Bernhardt, Guenther (2020) UR-DEBa242: A Py-5-Labeled Fluorescent Multipurpose Probe for Investigations on the Histamine H-3 and H-4 Receptors. JOURNAL OF MEDICINAL CHEMISTRY, 63 (10). pp. 5297-5311. ISSN 0022-2623, 1520-4804

Pegoli, Andrea and Wifling, David and Gruber, Corinna G. and She, Xueke and Huebner, Harald and Bernhardt, Guenther and Gmeiner, Peter and Keller, Max (2019) Conjugation of Short Peptides to Dibenzodiazepinone-Type Muscarinic Acetylcholine Receptor Ligands Determines M2R Selectivity. JOURNAL OF MEDICINAL CHEMISTRY, 62 (11). pp. 5358-5369. ISSN 0022-2623, 1520-4804

Maschauer, Simone and Ott, Julian J. and Bernhardt, Guenther and Kuwert, Torsten and Keller, Max and Prante, Olaf (2019) F-18-labelled triazolyl-linked argininamides targeting the neuropeptideYY(1)R for PET imaging of mammary carcinoma. SCIENTIFIC REPORTS, 9: 12990. ISSN 2045-2322

Bartole, Edith and Littmann, Timo and Tanaka, Miho and Ozawa, Takeaki and Buschauer, Armin and Bernhardt, Guenther (2019) [H-3]UR-DEBa176: A 2,4-Diaminopyrimidine-Type Radioligand Enabling Binding Studies at the Human, Mouse, and Rat Histamine H-4 Receptors. JOURNAL OF MEDICINAL CHEMISTRY, 62 (17). pp. 8338-8356. ISSN 0022-2623, 1520-4804

Schindler, Lisa and Bernhardt, Guenther and Keller, Max (2019) Modifications at Arg and Ile Give Neurotensin(8-13) Derivatives with High Stability and Retained NTS1 Receptor Affinity. ACS MEDICINAL CHEMISTRY LETTERS, 10 (6). pp. 960-965. ISSN 1948-5875

Yang, Zhenlin and Han, Shuo and Keller, Max and Kaiser, Anette and Bender, Brian J. and Bosse, Mathias and Burkert, Kerstin and Koegler, Lisa M. and Wifling, David and Bernhardt, Guenther and Plank, Nicole and Littmann, Timo and Schmidt, Peter and Yi, Cuiying and Li, Beibei and Ye, Sheng and Zhang, Rongguang and Xu, Bo and Larhammar, Dan and Stevens, Raymond C. and Huster, Daniel and Meiler, Jens and Zhao, Qiang and Beck-Sickinger, Annette G. and Buschauer, Armin and Wu, Beili (2018) Structural basis of ligand binding modes at the neuropeptide Y Y-1 receptor. NATURE, 556 (7702). 520-+. ISSN 0028-0836, 1476-4687

Jackson, Scott M. and Manolaridis, Ioannis and Kowal, Julia and Zechner, Melanie and Taylor, Nicholas M. I. and Bause, Manuel and Bauer, Stefanie and Bartholomaeus, Ruben and Bernhardt, Guenther and Koenig, Burkhard and Buschauer, Armin and Stahlberg, Henning and Altmann, Karl-Heinz and Locher, Kaspar P. (2018) Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. NATURE STRUCTURAL & MOLECULAR BIOLOGY, 25 (4). 333-+. ISSN 1545-9993, 1545-9985

Pena-Solorzano, Diana and Scholler, Matthias and Bernhardt, Guenther and Buschauer, Armin and Koenig, Burkhard and Ochoa-Puentes, Cristian (2018) Tariquidar-Related Chalcones and Ketones as ABCG2 Modulators. ACS MEDICINAL CHEMISTRY LETTERS, 9 (8). pp. 854-859. ISSN 1948-5875

Littmann, Timo and Ozawa, Takeaki and Hoffmann, Carsten and Buschauer, Armin and Bernhardt, Guenther (2018) A split luciferase-based probe for quantitative proximal determination of G alpha(q) signalling in live cells. SCIENTIFIC REPORTS, 8: 17179. ISSN 2045-2322

Dukorn, Stefanie and Littmann, Timo and Keller, Max and Kuhn, Kilian and Cabrele, Chiara and Baumeister, Paul and Bernhardt, Guenther and Buschauer, Armin (2017) Fluorescence- and Radiolabeling of [Lys(4),Nle(17,30)]hPP Yields Molecular Tools for the NPY Y-4 Receptor. BIOCONJUGATE CHEMISTRY, 28 (4). pp. 1291-1304. ISSN 1043-1802

She, Xueke and Pegoli, Andrea and Mayr, Judith and Huebner, Harald and Bernhardt, Guenther and Gmeiner, Peter and Keller, Max (2017) Heterodimerization of Dibenzodiazepinone-Type Muscarinic Acetylcholine Receptor Ligands Leads to Increased M2R Affinity and Selectivity. ACS OMEGA, 2 (10). pp. 6741-6754. ISSN 2470-1343

Keller, Max and Maschauer, Simone and Brennauer, Albert and Tripal, Philipp and Koglin, Norman and Dittrich, Ralf and Bernhardt, Guenther and Kuwert, Torsten and Wester, Hans-Juergen and Buschauer, Armin and Prante, Olaf (2017) Prototypic F-18-Labeled Argininamide-Type Neuropeptide Y Y1R Antagonists as Tracers for PET Imaging of Mammary Carcinoma. ACS MEDICINAL CHEMISTRY LETTERS, 8 (3). pp. 304-309. ISSN 1948-5875

Pegoli, Andrea and She, Xueke and Wifling, David and Huebner, Harald and Bernhardt, Guenther and Gmeiner, Peter and Keller, Max (2017) Radiolabeled Dibenzodiazepinone-Type Antagonists Give Evidence of Dualsteric Binding at the M-2 Muscarinic Acetylcholine Receptor. JOURNAL OF MEDICINAL CHEMISTRY, 60 (8). pp. 3314-3334. ISSN 0022-2623, 1520-4804

Edalat, Lena and Stegen, Benjamin and Klumpp, Lukas and Haehl, Erik and Schilbach, Karin and Lukowski, Robert and Kuehnle, Matthias and Bernhardt, Guenther and Buschauer, Armin and Zips, Daniel and Ruth, Peter and Huber, Stephan M. (2016) BK K+ channel blockade inhibits radiation-induced migration/brain infiltration of glioblastoma cells. ONCOTARGET, 7 (12). pp. 14259-14278. ISSN 1949-2553

Naporra, Franziska and Gobleder, Susanne and Wittmann, Hans Joachim and Spindler, Julia and Bodensteiner, Michael and Bernhardt, Guenther and Huebner, Harald and Gmeiner, Peter and Elz, Sigurd and Strasser, Andrea (2016) Dibenzo[bf][1,4]oxazepines and dibenzo[b,e]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H1R, H4R, 5-HT2AR and other selected GPCRs. PHARMACOLOGICAL RESEARCH, 113. pp. 610-625. ISSN 1043-6618

Obreque-Balboa, Jose Esteban and Sun, Qiu and Bernhardt, Guenther and Koenig, Burkhard and Buschauer, Armin (2016) Flavonoid derivatives as selective ABCC1 modulators: Synthesis and functional characterization. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 109. pp. 124-133. ISSN 0223-5234, 1768-3254

Kuhn, Kilian K. and Ertl, Thomas and Dukorn, Stefanie and Keller, Max and Bernhardt, Guenther and Reiser, Oliver and Buschauer, Armin (2016) High Affinity Agonists of the Neuropeptide Y (NPY) Y-4 Receptor Derived from the C-Terminal Pentapeptide of Human Pancreatic Polypeptide (hPP): Synthesis, Stereochemical Discrimination, and Radiolabeling. JOURNAL OF MEDICINAL CHEMISTRY, 59 (13). pp. 6045-6058. ISSN 0022-2623, 1520-4804

Keller, Max and Kuhn, Kilian K. and Einsiedel, Juergen and Huebner, Harald and Biselli, Sabrina and Mollereau, Catherine and Wifling, David and Svobodova, Jaroslava and Bernhardt, Guenther and Cabrele, Chiara and Vanderheyden, Patrick M. L. and Gmeiner, Peter and Buschauer, Armin (2016) Mimicking of Arginine by Functionalized N-omega-Carbamoylated Arginine As a New Broadly Applicable Approach to Labeled Bioactive Peptides: High Affinity Angiotensin, Neuropeptide Y, Neuropeptide FF, and Neurotensin Receptor Ligands As Examples. JOURNAL OF MEDICINAL CHEMISTRY, 59 (5). pp. 1925-1945. ISSN 0022-2623, 1520-4804

Kagermeier, Nicole and Werner, Kristin and Keller, Max and Baumeister, Paul and Bernhardt, Guenther and Seifert, Roland and Buschauer, Armin (2015) Dimeric carbamoylguanidine-type histamine H-2 receptor ligands: A new class of potent and selective agonists. BIOORGANIC & MEDICINAL CHEMISTRY, 23 (14). pp. 3957-3969. ISSN 0968-0896, 1464-3391

Huber, Stefan and Huettner, Johannes Philip and Hacker, Kristina and Bernhardt, Guenther and Koenig, Joerg and Buschauer, Armin (2015) Esters of Bendamustine Are by Far More Potent Cytotoxic Agents than the Parent Compound against Human Sarcoma and Carcinoma Cells. PLOS ONE, 10 (7): e0133743. ISSN 1932-6203

Wifling, David and Bernhardt, Guenther and Dove, Stefan and Buschauer, Armin (2015) The Extracellular Loop 2 (ECL2) of the Human Histamine H-4 Receptor Substantially Contributes to Ligand Binding and Constitutive Activity. PLOS ONE, 10 (1): e0117185. ISSN 1932-6203

Baumeister, Paul and Erdmann, Daniela and Biselli, Sabrina and Kagermeier, Nicole and Elz, Sigurd and Bernhardt, Guenther and Buschauer, Armin (2015) [H-3]UR-DE257: Development of a Tritium-Labeled Squaramide-Type Selective Histamine H-2 Receptor Antagonist. CHEMMEDCHEM, 10 (1). pp. 83-93. ISSN 1860-7179, 1860-7187

Rothenhoefer, Martin and Grundmann, Marco and Bernhardt, Guenther and Matysik, Frank-Michael and Buschauer, Armin (2015) High performance anion exchange chromatography with pulsed amperometric detection (HPAEC-PAD) for the sensitive determination of hyaluronan oligosaccharides. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 988. pp. 106-115. ISSN 1570-0232, 1873-376X

Beermann, Silke and Bernhardt, Guenther and Seifert, Roland and Buschauer, Armin and Neumann, Detlef (2015) Histamine H-1- and H-4-receptor signaling cooperatively regulate MAPK activation. BIOCHEMICAL PHARMACOLOGY, 98 (3). pp. 432-439. ISSN 0006-2952, 1873-2968

Keller, Max and Traenkle, Christian and She, Xueke and Pegoli, Andrea and Bernhardt, Guenther and Buschauer, Armin and Read, Roger W. (2015) M-2 Subtype preferring dibenzodiazepinone-type muscarinic receptor ligands: Effect of chemical homo-dimerization on orthosteric (and allosteric?) binding. BIOORGANIC & MEDICINAL CHEMISTRY, 23 (14). pp. 3970-3990. ISSN 0968-0896, 1464-3391

Huber, Stefan and Wege, Anja K. and Bernhardt, Guenther and Buschauer, Armin and Brockhoff, Gero (2015) Topotecan-induced ABCG2 expression in MCF-7 cells is associated with decreased CD24 and EpCAM expression and a loss of tumorigenicity. CYTOMETRY PART A, 87A (8). pp. 707-716. ISSN 1552-4922, 1552-4930

Keller, Max and Schindler, Lisa and Bernhardt, Guenther and Buschauer, Armin (2015) Toward Labeled Argininamide-Type NPY Y-1 Receptor Antagonists: Identification of a Favorable Propionylation Site in BIBO3304. ARCHIV DER PHARMAZIE, 348 (6). pp. 390-398. ISSN 0365-6233, 1521-4184

Pluym, Nikola and Baumeister, Paul and Keller, Max and Bernhardt, Guenther and Buschauer, Armin (2013) [3H]UR-PLN196: A Selective Nonpeptide Radioligand and Insurmountable Antagonist for the NeuropeptideY Y2Receptor. CHEMMEDCHEM, 8 (4). pp. 587-593. ISSN 1860-7179

Keller, Max and Kaske, Melanie and Holzammer, Tobias and Bernhardt, Guenther and Buschauer, Armin (2013) Dimeric argininamide-type neuropeptide Y receptor antagonists: Chiral discrimination between Y-1 and Y-4 receptors. BIOORGANIC & MEDICINAL CHEMISTRY, 21 (21). pp. 6303-6322. ISSN 0968-0896, 1464-3391

Nordemann, Uwe and Wifling, David and Schnell, David and Bernhardt, Guenther and Stark, Holger and Seifert, Roland and Buschauer, Armin (2013) Luciferase Reporter Gene Assay on Human, Murine and Rat Histamine H-4 Receptor Orthologs: Correlations and Discrepancies between Distal and Proximal Readouts. PLOS ONE, 8 (9): e73961. ISSN 1932-6203

Bauer, Stefanie and Ochoa-Puentes, Cristian and Sun, Qiu and Bause, Manuel and Bernhardt, Guenther and Koenig, Burkhard and Buschauer, Armin (2013) Quinoline Carboxamide-Type ABCG2 Modulators: Indole and Quinoline Moieties as Anilide Replacements. CHEMMEDCHEM, 8 (11). pp. 1773-1778. ISSN 1860-7179, 1860-7187

Berlicki, Lukasz and Kaske, Melanie and Gutierrez-Abad, Raquel and Bernhardt, Guenther and Illa, Ona and Ortuno, Rosa M. and Cabrele, Chiara and Buschauer, Armin and Reiser, Oliver (2013) Replacement of Thr(32) and GIn(34) in the C-Terminal Neuropeptide Y Fragment 25-36 by cis-Cyclobutane and cis-Cyclopentane beta-Amino Acids Shifts Selectivity toward the Y-4 Receptor. JOURNAL OF MEDICINAL CHEMISTRY, 56 (21). pp. 8422-8431. ISSN 0022-2623, 1520-4804

Birnkammer, Tobias and Spickenreither, Anja and Brunskole, Irena and Lopuch, Miroslaw and Kagermeier, Nicole and Bernhardt, Guenther and Dove, Stefan and Seifert, Roland and Elz, Sigurd and Buschauer, Armin (2012) The Bivalent Ligand Approach Leads to Highly Potent and Selective Acylguanidine-Type Histamine H-2 Receptor Agonists. JOURNAL OF MEDICINAL CHEMISTRY, 55 (3). pp. 1147-1160. ISSN 0022-2623, 1520-4804

Grundmann, Marco and Rothenhoefer, Martin and Bernhardt, Guenther and Buschauer, Armin and Matysik, Frank-Michael (2012) Fast counter-electroosmotic capillary electrophoresis-time-of-flight mass spectrometry of hyaluronan oligosaccharides. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 402 (8). pp. 2617-2623. ISSN 1618-2642

Posavec, Damir and Zabel, Manfred and Bogner, Udo and Bernhardt, Guenther and Knoer, Guenther (2012) Functionalized derivatives of 1,4-dimethylnaphthalene as precursors for biomedical applications: synthesis, structures, spectroscopy and photochemical activation in the presence of dioxygen. ORGANIC & BIOMOLECULAR CHEMISTRY, 10 (35). pp. 7062-7069. ISSN 1477-0520

Memminger, Martin and Keller, Max and Lopuch, Miroslaw and Pop, Nathalie and Bernhardt, Guenther and von Angerer, Erwin and Buschauer, Armin (2012) The Neuropeptide Y Y-1 Receptor: A Diagnostic Marker? Expression in MCF-7 Breast Cancer Cells Is Down-Regulated by Antiestrogens In Vitro and in Xenografts. PLOS ONE, 7 (12): e51032. ISSN 1932-6203

Rothenhoefer, Martin and Scheruebl, Rosmarie and Bernhardt, Guenther and Heilmann, Joerg and Buschauer, Armin (2012) Qualitative and quantitative analysis of hyaluronan oligosaccharides with high performance thin layer chromatography using reagent-free derivatization on amino-modified silica and electrospray ionization-quadrupole time-of-flight mass spectrometry coupling on normal phase. JOURNAL OF CHROMATOGRAPHY A, 1248. pp. 169-177. ISSN 0021-9673, 1873-3778

Pluym, Nikola and Brennauer, Albert and Keller, Max and Ziemek, Ralf and Pop, Nathalie and Bernhardt, Guenther and Buschauer, Armin (2011) Application of the Guanidine-Acylguanidine Bioisosteric Approach to Argininamide-Type NPY Y-2 Receptor Antagonists. CHEMMEDCHEM, 6 (9). pp. 1727-1738. ISSN 1860-7179

Braun, Stephan and Botzki, Alexander and Salmen, Sunnhild and Textor, Christian and Bernhardt, Guenther and Dove, Stefan and Buschauer, Armin (2011) Design of benzimidazole- and benzoxazole-2-thione derivatives as inhibitors of bacterial hyaluronan lyase. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 46 (9). pp. 4419-4429. ISSN 0223-5234

Pop, Nathalie and Igel, Patrick and Brennauer, Albert and Cabrele, Chiara and Bernhardt, Guenther and Seifert, Roland and Buschauer, Armin (2011) Functional reconstitution of human neuropeptide Y (NPY) Y-2 and Y-4 receptors in Sf9 insect cells. JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, 31 (4). pp. 271-285. ISSN 1079-9893, 1532-4281

Keller, Max and Bernhardt, Guenther and Buschauer, Armin (2011) [H-3]UR-MK136: A Highly Potent and Selective Radioligand for Neuropeptide Y Y-1 Receptors. CHEMMEDCHEM, 6 (9). pp. 1566-1571. ISSN 1860-7179, 1860-7187

Posavec, Damir and Dorsch, Andre and Bogner, Udo and Bernhardt, Guenther and Nagl, Stefan (2011) Polyvinyl butyral nanobeads: preparation, characterization, biocompatibility and cancer cell uptake. MICROCHIMICA ACTA, 173 (3-4). pp. 391-399. ISSN 0026-3672

Keller, Max and Erdmann, Daniela and Pop, Nathalie and Pluym, Nikola and Teng, Shangjun and Bernhardt, Guenther and Buschauer, Armin (2011) Red-fluorescent argininamide-type NPY Y-1 receptor antagonists as pharmacological tools. BIOORGANIC & MEDICINAL CHEMISTRY, 19 (9). pp. 2859-2878. ISSN 0968-0896, 1464-3391

Weiss, Stefan and Bernhardt, Guenther and Buschauer, Armin and Koenig, Burkhard (2011) SYNTHESIS AND CHARACTERIZATION OF DMAP-MODIFIED NPY Y-1 RECEPTOR ANTAGONISTS AS ACYL-TRANSFER CATALYSTS. COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 76 (6). pp. 763-780. ISSN 0010-0765

Puentes, Cristian Ochoa and Hoecherl, Peter and Kuehnle, Matthias and Bauer, Stefanie and Buerger, Kira and Bernhardt, Guenther and Buschauer, Armin and Koenig, Burkhard (2011) Solid phase synthesis of tariquidar-related modulators of ABC transporters preferring breast cancer resistance protein (ABCG2). BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 21 (12). pp. 3654-3657. ISSN 0960-894X, 1464-3405

Ghorai, Prasanta and Kraus, Anja and Birnkammer, Tobias and Geyer, Roland and Bernhardt, Guenther and Dove, Stefan and Seifert, Roland and Elz, Sigurd and Buschauer, Armin (2010) Chiral N-G-acylated hetarylpropylguanidine-type histamine H-2 receptor agonists do not show significant stereoselectivity. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 20 (10). pp. 3173-3176. ISSN 0960-894X

Weiss, Stefan and Keller, Max and Bernhardt, Guenther and Buschauer, Armin and Koenig, Burkhard (2010) N-G-Acyl-argininamides as NPY Y-1 receptor antagonists: Influence of structurally diverse acyl substituents on stability and affinity. BIOORGANIC & MEDICINAL CHEMISTRY, 18 (17). pp. 6292-6304. ISSN 0968-0896

Keller, Max and Teng, Shangjun and Bernhardt, Guenther and Buschauer, Armin (2009) Bivalent Argininamide-Type Neuropeptide Y Y-1 Antagonists Do Not Support the Hypothesis of Receptor Dimerisation. CHEMMEDCHEM, 4 (10). pp. 1733-1745. ISSN 1860-7179

Kraus, Anja and Ghorai, Prasanta and Birnkammer, Tobias and Schnell, David and Elz, Sigurd and Seifert, Roland and Dove, Stefan and Bernhardt, Guenther and Buschauer, Armin (2009) N-G-Acylated Aminothiazolylpropylguanidines as Potent and Selective Histamine H-2 Receptor Agonists. CHEMMEDCHEM, 4 (2). pp. 232-240. ISSN 1860-7179

Kuehnle, Matthias and Egger, Michael and Mueller, Christine and Mahringer, Anne and Bernhardt, Guenther and Fricker, Gert and Koenig, Burkhard and Buschauer, Armin (2009) Potent and Selective Inhibitors of Breast Cancer Resistance Protein (ABCG2) Derived from the p-Glycoprotein (ABCB1) Modulator Tariquidar. JOURNAL OF MEDICINAL CHEMISTRY, 52 (4). pp. 1190-1197. ISSN 0022-2623, 1520-4804

Igel, Patrick and Schnell, David and Bernhardt, Guenther and Seifert, Roland and Buschauer, Armin (2009) Tritium-Labeled N-1-[3-(1H-imidazol-4-yl)propyl]-N-2-propionylguanidine ([H-3]UR-PI294), a High-Affinity Histamine H-3 and H-4 Receptor Radioligand. CHEMMEDCHEM, 4 (2). pp. 225-231. ISSN 1860-7179, 1860-7187

Ghorai, Prasanta and Kraus, Anja and Keller, Max and Goette, Carsten and Igel, Patrick and Schneider, Erich and Schnell, David and Bernhardt, Guenther and Dove, Stefan and Zabel, Manfred and Elz, Sigurd and Seifert, Roland and Buschauer, Armin (2008) Acylguanidines as Bioisosteres of Guanidines: N-G-Acylated Imidazolylpropylguanidines, a New Class of Histamine H-2 Receptor Agonists. JOURNAL OF MEDICINAL CHEMISTRY, 51 (22). pp. 7193-7204. ISSN 0022-2623, 1520-4804

Kutta, Roger J. and Hofinger, Edith S. A. and Preuss, Hendrik and Bernhardt, Guenther and Dick, Bernhard (2008) Blue-light induced interaction of LOV domains from Chlamydomonas reinhardtii. CHEMBIOCHEM, 9 (12). pp. 1931-1938. ISSN 1439-4227, 1439-7633

Hubensack, Martina and Mueller, Christine and Hoecherl, Peter and Fellner, Stephan and Spruss, Thilo and Bernhardt, Guenther and Buschauer, Armin (2008) Effect of the ABCB1 modulators elacridar and tariquidar on the distribution of paclitaxel in nude mice. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 134 (5). pp. 597-607. ISSN 0171-5216

Keller, Max and Pop, Nathalie and Hutzler, Christoph and Beck-Sickinger, Annette G. and Bernhardt, Guenther and Buschauer, Armin (2008) Guanidine-Acylguanidine Bioisosteric Approach in the Design of Radioligands: Synthesis of a Tritium-Labeled N-G-Propionylargininamide ([H-3]-UR-MK114) as a Highly Potent and Selective Neuropeptide Y Y-1 Receptor Antagonist. JOURNAL OF MEDICINAL CHEMISTRY, 51 (24). pp. 8168-8172. ISSN 0022-2623

Hofinger, Edith S. A. and Hoechstetter, Julia and Oettl, Martin and Bernhardt, Guenther and Buschauer, Armin (2008) Isoenzyme-specific differences in the degradation of hyaluronic acid by mammalian-type hyaluronidases. GLYCOCONJUGATE JOURNAL, 25 (2). pp. 101-109. ISSN 0282-0080, 1573-4986

Weiss, Stefan and Keller, Max and Bernhardt, Guenther and Buschauer, Armin and Koenig, Burkhard (2008) Modular synthesis of non-peptidic bivalent NPY Y-1 receptor antagonists. BIOORGANIC & MEDICINAL CHEMISTRY, 16 (22). pp. 9858-9866. ISSN 0968-0896

Brennauer, Albert and Keller, Max and Freund, Matthias and Bernhardt, Guenther and Buschauer, Armin (2007) Decomposition of 1-(omega-aminoalkanoyl)guanidines under alkaline conditions. TETRAHEDRON LETTERS, 48 (39). pp. 6996-6999. ISSN 0040-4039

Ziemek, Ralf and Schneider, Erich and Kraus, Anja and Cabrele, Chiara and Beck-Sickinger, Annette G. and Bernhardt, Guenther and Buschauer, Armin (2007) Determination of affinity and activity of ligands at the human neuropeptide y Y-4 receptor by flow cytometry and aequorin luminescence. JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, 27 (4). pp. 217-233. ISSN 1079-9893

Mueller, Christine and Gross, Dietmar and Sarli, Vasiliki and Gartner, Michael and Giannis, Athanassios and Bernhardt, Guenther and Buschauer, Armin (2007) Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells. CANCER CHEMOTHERAPY AND PHARMACOLOGY, 59 (2). pp. 157-164. ISSN 0344-5704

Hofinger, Edith S. A. and Bernhardt, Guenther and Buschauer, Armin (2007) Kinetics of Hyal-1 and PH-20 hyaluronidases: Comparison of minimal substrates and analysis of the transglycosylation reaction. GLYCOBIOLOGY, 17 (9). pp. 963-971. ISSN 0959-6658, 1460-2423

Hofinger, Edith S. A. and Spickenreither, Martin and Oschmann, Jan and Bernhardt, Guenther and Rudolph, Rainer and Buschauer, Armin (2007) Recombinant human hyaluronidase Hyal-1: insect cells versus Escherichia coli as expression system and identification of low molecular weight inhibitors. GLYCOBIOLOGY, 17 (4). pp. 444-453. ISSN 0959-6658, 1460-2423

Egger, Michael and Li, Xuqin and Mueller, Christine and Bernhardt, Guenther and Buschauer, Armin and Koenig, Burkhard (2007) Tariquidar analogues: Synthesis by Cu-I-catlyzed N/O-aryl coupling and inhibitory activity against the ABCB1 transporter. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (16). pp. 2643-2649. ISSN 1434-193X, 1099-0690

Rigden, Daniel J. and Botzki, Alexander and Nukui, Masatoshi and Mewbourne, R. Brandon and Lamani, Ejvis and Braun, Stephan and von Angerer, Erwin and Bernhardt, Guenther and Dove, Stefan and Buschauer, Armin and Jedrzejas, Mark J. (2006) Design of new benzoxazole-2-thione-derived inhibitors of Streptococcus pneumoniae hyaluronan lyase: structure of a complex with a 2-phenylindole. GLYCOBIOLOGY, 16 (8). pp. 757-765. ISSN 0959-6658

Spickenreither, Martin and Braun, Stephan and Bernhardt, Guenther and Dove, Stefan and Buschauer, Armin (2006) Novel 6-O-acylated vitamin C derivatives as hyaluronidase inhibitors with selectivity for bacterial lyases. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 16 (20). pp. 5313-5316. ISSN 0960-894X

Xie, Sheng-Xue and Petrache, Georgiana and Schneider, Erich and Ye, Qi-Zhuang and Bernhardt, Guenther and Seifert, Roland and Buschauer, Armin (2006) Synthesis and pharmacological characterization of novel fluorescent histamine H-2-receptor ligands derived from aminopotentidine. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 16 (15). pp. 3886-3890. ISSN 0960-894X

Schneider, Erich and Mayer, Matthias and Ziemek, Ralf and Li, antao Li and Hutzler, Christoph and Bernhardt, Guenther and Buschauer, Armin (2006) A simple and powerful flow cytometric method for the simultaneous determination of multiple parameters at g protein-coupled receptor subtypes. CHEMBIOCHEM, 7 (9). pp. 1400-1409. ISSN 1439-4227

Salmen, Sunnhild and Hoechstetter, Julia and Kaesbauer, Christian and Paper, Dieter H. and Bernhardt, Guenther and Buschauer, Armin (2005) Sulphated oligosaccharides as inhibitors of hyaluronidases from bovine testis, bee venom and Streptococcus agalactiae. PLANTA MEDICA, 71 (8). pp. 727-732. ISSN 0032-0943, 1439-0221

Schertl, Sabine and Hartmann, Rolf W. and Batzl-Hartmann, Christine and Bernhardt, Guenther and Spruss, Thilo and Beckenlehner, Karin and Koch, Marion and Krauser, Rudolf and Schlemmer, Richard and Gust, Ronald and Schoenberger, Helmut (2004) [1,2-bis(2,6-difluoro-3-hydroxyphenyl)ethylenediamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - Mode of action I: Antitumor activity due to the reduction of the endogenous estrogen level. ARCHIV DER PHARMAZIE, 337 (6). pp. 335-348. ISSN 0365-6233, 1521-4184

Schertl, Sabine and Hartmann, Rolf W. and Batzl-Hartmann, Christine and Bernhardt, Guenther and Spruss, Thilo and Beckenlehner, Karin and Koch, Marion and Krauser, Rudolf and Schlemmer, Richard and Gust, Ronald and Schonenberger, Helmut (2004) [1,2-bis(2,6-difluoro-3-hydroxyphenyl)ethylenediamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - Mode of action II: Contribution of drug inactivation, cellular drug uptake and sterical factors in the drug-target interaction to the antitumor activity. ARCHIV DER PHARMAZIE, 337 (6). pp. 349-359. ISSN 0365-6233, 1521-4184

Bernhardt, Guenther and Brunner, Henri and Gruber, Nick and Lottner, Christian and Pushpan, Simi K. and Tsuno, Takashi and Zabel, Manfred (2004) Carboplatin derivatives with superior antitumor activity compared to the parent compound. INORGANICA CHIMICA ACTA, 357 (15). pp. 4452-4466. ISSN 0020-1693, 1873-3255

Lottner, Christian and Knuechel, Ruth and Bernhardt, Guenther and Brunner, Henri (2004) Combined chemotherapeutic and photodynamic treatment on human bladder cells by hematoporphyrin-platinum(II) conjugates. CANCER LETTERS, 203 (2). pp. 171-180. ISSN 0304-3835

Lottner, Christian and Knuechel, Ruth and Bernhardt, Guenther and Brunner, Henri (2004) Distribution and subcellular localization of a water-soluble hematoporphyrin-platinum(II) complex in human bladder cancer cells. CANCER LETTERS, 215 (2). pp. 167-177. ISSN 0304-3835

Botzki, Alexander and Rigden, Daniel J. and Braun, Stephan and Nukui, Masatoshi and Salmen, Sunnhild and Hoechstetter, Julia and Bernhardt, Guenther and Dove, Stefan and Jedrzejas, Mark J. and Buschauer, Armin (2004) L-ascorbic acid 6-hexadecanoate, a potent hyaluronidase inhibitor - X-ray structure and molecular modeling of enzyme-inhibitor complexes. JOURNAL OF BIOLOGICAL CHEMISTRY, 279 (44). pp. 45990-45997. ISSN 0021-9258, 1083-351X

Li, L. T. and Mayer, Matthias and Schneider, Erich and Schreiber, Elvira and Bernhardt, Guenther and Peng, S. Q. and Buschauer, Armin (2003) Preparation of fluorescent nonpeptidic neuropeptide Y receptor ligands: Analogues of the quinazoline-type anti-obesity Y-5 antagonist CGP 71683A. ARCHIV DER PHARMAZIE, 336 (12). pp. 585-590. ISSN 0365-6233, 1521-4184

Lottner, Christian and Bart, Karl-Christian and Bernhardt, Guenther and Brunner, Henri (2002) Hematoporphyrin-derived soluble porphyrin-platinum conjugates with combined cytotoxic and phototoxic antitumor activity. JOURNAL OF MEDICINAL CHEMISTRY, 45 (10). pp. 2064-2078. ISSN 0022-2623, 1520-4804

Weiss, Thomas S. and Bernhardt, Guenther and Buschauer, Armin and Thasler, Wolfgang E. and Dolgner, Doris and Zirngibl, Hubert and Jauch, Karl-Walter (2002) Polyamine levels of human colorectal adenocarcinomas are correlated with tumor stage and grade. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 17 (6). pp. 381-387. ISSN 0179-1958, 1432-1262

Fellner, Stephan and Bauer, Bjoern and Miller, David S. and Schaffrik, Martina and Fankhaenel, Martina and Spruss, Thilo and Bernhardt, Guenther and Graeff, Claudia and Faerber, Lothar and Gschaidmeier, Harald and Buschauer, Armin and Fricker, Gert (2002) Transport of paclitaxel (Taxol) across the blood-brain barrier in vitro and in vivo. JOURNAL OF CLINICAL INVESTIGATION, 110 (9). pp. 1309-1318. ISSN 0021-9738, 1558-8238

Schertl, Sabine and Hartmann, Rolf W. and Batzl-Hartmann, Christine and Schlemmer, Richard and Spruss, Thilo and Bernhardt, Guenther and Gust, Ronald and Schoenenberger, Helmut (2001) 1-(2,6-dichloro-4-hydroxyphenyl)-2-phenylethanes - New biological response modifiers for the therapy of breast cancer. Synthesis and evaluation of estrogenic/antiestrogenic properties. ARCHIV DER PHARMAZIE, 334 (4). pp. 125-137. ISSN 0365-6233

Schuster, Andreas and Goette, Carsten and Bernhardt, Guenther and Buschauer, Armin (2001) Chiral separation of pheniramine-like 3-phenyl-3-heteroarylpropylamines by CE and HPLC methods. CHIRALITY, 13 (6). pp. 285-293. ISSN 0899-0042

Schlemmer, Richard and Spruss, Thilo and Bernhardt, Guenther and Schoenenberger, Helmut (2000) Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl) ethylenediamine]dichloroplatinum(II) act on the hormone-sensitive, murine breast cancer as a biological response modifier? Part 1: The MXT-M-3.2 breast cancer stimulates the growth of an identical second graft; [Meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]dichloroplatinum(II) inhibits this process. ARCHIV DER PHARMAZIE, 333 (2-3). pp. 69-71. ISSN 0365-6233

Schlemmer, Richard and Spruss, Thilo and Bernhardt, Guenther and Schoenenberger, Helmut (2000) Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]-dichloro-platinum(II) act as an immune response modifier? Part III: Progressively growing MXT-M-3,2 breast cancer stimulates the proliferation of phagocytes in B6D2F(1) mice. ARCHIV DER PHARMAZIE, 333 (12). pp. 404-414. ISSN 0365-6233, 1521-4184

Schlemmer, Richard and Spruss, Thilo and Bernhardt, Guenther and Schoenenberger, Helmut (2000) Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]-dichloroplatinum(II) act on the hormone-sensitive, murine breast cancer as a biological response modifier? Part II. Studies on the influence of [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]dichloroplatinum(II) on the specific immune defense in MXT-M-3,2 breast cancer bearing mice. ARCHIV DER PHARMAZIE, 333 (12). pp. 397-403. ISSN 0365-6233

Meister, Adolf and Bernhardt, Guenther and Christoffel, Volker and Buschauer, Armin (1999) Antispasmodic activity of Thymus vulgaris extract on the isolated guinea-pig trachea: Discrimination between drug and ethanol effects. PLANTA MEDICA, 65 (6). pp. 512-516. ISSN 0032-0943,

Schlemmer, Richard and Spruss, Thilo and Bernhardt, Guenther and Schoenenberger, Helmut (1999) [meso-1,2-Bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a compound with a specific activity on hormone-sensitive breast cancers - Evidence for a diethylstilbestrol-like mode of action. ARCHIV DER PHARMAZIE, 332 (2). pp. 59-69. ISSN 0365-6233,

Bernhardt, Guenther and Koch, Marion and Spruss, Thilo and Gust, Ronald and Krauser, Rudolf and Schlemmer, Richard and Hollstein, Michael and Lux, Franz and Schoenenberger, Helmut (1999) [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]sulfatoplatinum(II) - Pharmacokinetic studies. ARCHIV DER PHARMAZIE, 332 (6). pp. 195-200. ISSN 0365-6233,

Gust, Ronald and Schnurr, Beate and Krauser, Rudolf and Bernhardt, Guenther and Koch, Marion and Schmid, Beate and Hummel, Evelyn and Schoenenberger, Helmut (1998) Stability and cellular studies of [rac-1,2-bis(4-f luorophenyl)-ethylenediamine][cyclobutane-1,1-dicarboxylato]platinum(II), a novel, highly active carboplatin derivative. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 124 (11). pp. 585-597. ISSN 0171-5216,

Conference or Workshop Item

Hoering, Carina and Seibel, Ulla and Littmann, Timo and Graetz, Lukas and Strasser, Andrea and Bernhardt, Guenther (2020) A MiniG Protein Recruitment Assay for the Histamine Receptor Family to Functionally Characterize Histamine Receptor Ligands. In: Annual Meeting on Experimental Biology, APR 04-07, 2020, San Diego, CA.