Items where Author is "Cigliano, Antonio"

Article

Mi, Wunan and Cigliano, Antonio and Galleri, Grazia and Gigante, Isabella and Steinmann, Sara Martina and Cibali, Ezgi and Serra, Marina and Pes, Giovanni Mario and Schloesser, Denise and Pizzuto, Elena and Siegmund, Heiko I. and Fischer, Claudia and Saborowski, Anna and Giannelli, Gianluigi and Evert, Matthias and Laan, Luc Johannes Wilhelmus van der and Verstegen, Monique Maria Andrea and Calvisi, Diego Francesco (2025) Targeting EIF4A1 is effective against human intrahepatic cholangiocarcinoma. JHEP REPORTS, 7 (7): 101416. ISSN , 2589-5559

Cigliano, Antonio and Simile, Maria M. and Vidili, Gianpaolo and Pes, Giovanni M. and Dore, Maria P. and Urigo, Francesco and Cossu, Eleonora and Che, Li and Feo, Claudio and Steinmann, Sara M. and Ribback, Silvia and Pascale, Rosa M. and Evert, Matthias and Chen, Xin and Calvisi, Diego F. (2024) Fatty Acid Synthase Promotes Hepatocellular Carcinoma Growth via S-Phase Kinase-Associated Protein 2/p27<SUP>KIP1</SUP> Regulation. MEDICINA-LITHUANIA, 60 (7): 1160. ISSN 1010-660X, 1648-9144

Cigliano, Antonio and Gigante, Isabella and Serra, Marina and Vidili, Gianpaolo and Simile, Maria M. and Steinmann, Sara and Urigo, Francesco and Cossu, Eleonora and Pes, Giovanni M. and Dore, Maria P. and Ribback, Silvia and Milia, Egle P. and Pizzuto, Elena and Mancarella, Serena and Che, Li and Pascale, Rosa M. and Giannelli, Gianluigi and Evert, Matthias and Chen, Xin and Calvisi, Diego F. (2024) HSF1 is a prognostic determinant and therapeutic target in intrahepatic cholangiocarcinoma. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 43 (1): 253. ISSN , 1756-9966

Steinmann, Sara M. and Sanchez-Martin, Anabel and Tanzer, Elisabeth and Cigliano, Antonio and Pes, Giovanni M. and Simile, Maria M. and Desaubry, Laurent and Marin, Jose J. G. and Evert, Matthias and Calvisi, Diego F. (2023) eIF4A1 Is a Prognostic Marker and Actionable Target in Human Hepatocellular Carcinoma. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (3): 2055. ISSN 1661-6596, 1422-0067

Mancarella, Serena and Serino, Grazia and Gigante, Isabella and Cigliano, Antonio and Ribback, Silvia and Sanese, Paola and Grossi, Valentina and Simone, Cristiano and Armentano, Raffaele and Evert, Matthias and Calvisi, Diego F. and Giannelli, Gianluigi (2022) CD90 is regulated by notch1 and hallmarks a more aggressive intrahepatic cholangiocarcinoma phenotype. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 41 (1): 65. ISSN , 1756-9966

Cigliano, Antonio and Zhang, Shanshan and Ribback, Silvia and Steinmann, Sara and Sini, Marcella and Ament, Cindy E. and Utpatel, Kirsten and Song, Xinhua and Wang, Jingxiao and Pilo, Maria G. and Berger, Fabian and Wang, Haichuan and Tao, Junyan and Li, Xiaolei and Pes, Giovanni M. and Mancarella, Serena and Giannelli, Gianluigi and Dombrowski, Frank and Evert, Matthias and Calvisi, Diego F. and Chen, Xin and Evert, Katja (2022) The Hippo pathway effector TAZ induces intrahepatic cholangiocarcinoma in mice and is ubiquitously activated in the human disease. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 41 (1): 192. ISSN , 1756-9966

Scheiter, Alexander and Evert, Katja and Reibenspies, Lucas and Cigliano, Antonio and Annweiler, Katharina and Mueller, Karolina and Poehmerer, Laura-Maria-Giovanna and Xu, Hongwei and Cui, Guofei and Itzel, Timo and Materna-Reichelt, Silvia and Coluccio, Andrea and Honarnejad, Kamran and Teufel, Andreas and Brochhausen, Christoph and Dombrowski, Frank and Chen, Xin and Evert, Matthias and Calvisi, Diego F. and Utpatel, Kirsten (2022) RASSF1A independence and early galectin-1 upregulation in PIK3CA-induced hepatocarcinogenesis: new therapeutic venues. MOLECULAR ONCOLOGY, 16 (5). pp. 1091-1118. ISSN 1574-7891, 1878-0261

Wang, Haichuan and Zhang, Shanshan and Zhang, Yi and Jia, Jiaoyuan and Wang, Jingxiao and Liu, Xianqiong and Zhang, Jie and Song, Xinhua and Ribback, Silvia and Cigliano, Antonio and Evert, Matthias and Liang, Bingyong and Wu, Hong and Calvisi, Diego F. and Zeng, Yong and Chen, Xin (2022) TAZ is indispensable for c-MYC-induced hepatocarcinogenesis. JOURNAL OF HEPATOLOGY, 76 (1). pp. 123-134. ISSN 0168-8278, 1600-0641

Shang, Runze and Song, Xinhua and Wang, Pan and Zhou, Yi and Lu, Xinjun and Wang, Jingxiao and Xu, Meng and Chen, Xinyan and Utpatel, Kirsten and Che, Li and Liang, Binyong and Cigliano, Antonio and Evert, Matthias and Calvisi, Diego F. and Chen, Xin (2021) Cabozantinib-based combination therapy for the treatment of hepatocellular carcinoma. GUT, 70 (9). pp. 1746-1757. ISSN 0017-5749, 1468-3288

Cigliano, Antonio and Chen, Xin and Calvisi, Diego F. (2021) Current challenges to underpinning the genetic basis for cholangiocarcinoma. EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 15 (5). pp. 511-526. ISSN 1747-4124, 1747-4132

Wang, Haichuan and Wang, Jingxiao and Zhang, Shanshan and Jia, Jiaoyuan and Liu, Xianqiong and Zhang, Jie and Wang, Pan and Song, Xinhua and Che, Li and Liu, Ke and Ribback, Silvia and Cigliano, Antonio and Evert, Matthias and Wu, Hong and Calvisi, Diego F. and Zeng, Yong and Chen, Xin (2021) Distinct and Overlapping Roles of Hippo Effectors YAP and TAZ During Human and Mouse Hepatocarcinogenesis. CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 11 (4). pp. 1095-1117. ISSN 2352-345X,

Wang, Haichuan and Song, Xinhua and Liao, Haotian and Wang, Pan and Zhang, Yi and Che, Li and Zhang, Jie and Zhou, Yi and Cigliano, Antonio and Ament, Cindy and Superville, Daphne and Ribback, Silvia and Reeves, Melissa and Pes, Giovanni M. and Liang, Binyong and Wu, Hong and Evert, Matthias and Calvisi, Diego F. and Zeng, Yong and Chen, Xin (2021) Overexpression of Mothers Against Decapentaplegic Homolog 7 Activates the Yes-Associated Protein/NOTCH Cascade and Promotes Liver Carcinogenesis in Mice and Humans. HEPATOLOGY, 74 (1). pp. 248-263. ISSN 0270-9139, 1527-3350

Che, Li and Chi, Wenna and Qiao, Yu and Zhang, Jie and Song, Xinhua and Liu, Ye and Li, Lei and Jia, Jiaoyuan and Pilo, Maria G. and Wang, Jingxiao and Cigliano, Antonio and Ma, Zhilong and Kuang, Wenhua and Tang, Zefang and Zhang, Zemin and Shui, Guanghou and Ribback, Silvia and Dombrowski, Frank and Evert, Matthias and Pascale, Rosa Maria and Cossu, Carla and Pes, Giovanni Mario and Osborne, Timothy F. and Calvisi, Diego F. and Chen, Xin and Chen, Ligong (2020) Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans. GUT, 69 (1). pp. 177-186. ISSN 0017-5749, 1468-3288

Mancarella, Serena and Serino, Grazia and Dituri, Francesco and Cigliano, Antonio and Ribback, Silvia and Wang, Jingxiao and Chen, Xin and Calvisi, Diego F. and Giannelli, Gianluigi (2020) Crenigacestat, a selective NOTCH1 inhibitor, reduces intrahepatic cholangiocarcinoma progression by blocking VEGFA/DLL4/MMP13 axis. CELL DEATH AND DIFFERENTIATION, 27 (8). pp. 2330-2343. ISSN 1350-9047, 1476-5403

Zhang, Shu and Zhang, Jie and Evert, Katja and Li, Xiaolei and Liu, Pin and Kiss, Andras and Schaff, Zsuzsa and Ament, Cindy and Zhang, Yi and Serra, Monica and Evert, Matthias and Chen, Nianyong and Xu, Feng and Chen, Xin and Tao, and Calvisi, Diego F. and Cigliano, Antonio (2020) The Hippo Effector Transcriptional Coactivator with PDZ-Binding Motif Cooperates with Oncogenic beta-Catenin to Induce Hepatoblastoma Development in Mice and Humans. AMERICAN JOURNAL OF PATHOLOGY, 190 (7). pp. 1397-1413. ISSN 0002-9440, 1525-2191

Cigliano, Antonio and Pilo, Maria Giulia and Mela, Marta and Ribback, Silvia and Dombrowski, Frank and Pes, Giovanni Mario and Cossu, Antonio and Evert, Matthias and Calvisi, Diego Francesco and Utpatel, Kirsten (2020) Inhibition of MELK Protooncogene as an Innovative Treatment for Intrahepatic Cholangiocarcinoma. MEDICINA-LITHUANIA, 56 (1): 1. ISSN 1010-660X, 1648-9144

Jia, Jiaoyuan and Che, Li and Cigliano, Antonio and Wang, Xue and Peitta, Graziella and Tao, Junyan and Zhong, Sheng and Ribback, Silvia and Evert, Matthias and Chen, Xin and Calvisi, Diego F. (2020) Pivotal Role of Fatty Acid Synthase in c-MYC Driven Hepatocarcinogenesis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21 (22): 8467. ISSN 1422-0067

Metzendorf, Christoph and Wineberger, Katharina and Rausch, Jenny and Cigliano, Antonio and Peters, Kristin and Sun, Baodong and Mennerich, Daniela and Kietzmann, Thomas and Calvisi, Diego F. and Dombrowski, Frank and Ribback, Silvia (2020) Transcriptomic and Proteomic Analysis of Clear Cell Foci (CCF) in the Human Non-Cirrhotic Liver Identifies Several Differentially Expressed Genes and Proteins with Functions in Cancer Cell Biology and Glycogen Metabolism. MOLECULES, 25 (18): 4141. ISSN 1420-3049

Song, Xinhua and Liu, Xianqiong and Wang, Haichuan and Wang, Jingxiao and Qiao, Yu and Cigliano, Antonio and Utpatel, Kirsten and Ribback, Silvia and Pilo, Maria G. and Serra, Marina and Gordan, John D. and Che, Li and Zhang, Shanshan and Cossu, Antonio and Porcu, Alberto and Pascale, Rosa M. and Dombrowski, Frank and Hu, Hongbo and Calvisi, Diego F. and Evert, Matthias and Chen, Xin (2019) Combined CDK4/6 and Pan-mTOR Inhibition Is Synergistic Against Intrahepatic Cholangiocarcinoma. CLINICAL CANCER RESEARCH, 25 (1). pp. 403-413. ISSN 1078-0432, 1557-3265

Wang, Jingxiao and Wang, Haichuan and Peters, Michele and Ding, Ning and Ribback, Silvia and Utpatel, Kirsten and Cigliano, Antonio and Dombrowski, Frank and Xu, Meng and Chen, Xinyan and Song, Xinhua and Che, Li and Evert, Matthias and Cossu, Antonio and Gordan, John and Zeng, Yong and Chen, Xin and Calvisi, Diego F. (2019) Loss of Fbxw7 synergizes with activated Akt signaling to promote c-Myc dependent cholangiocarcinogenesis. JOURNAL OF HEPATOLOGY, 71 (4). pp. 742-752. ISSN 0168-8278, 1600-0641

Wang, Pan and Song, Xinhua and Utpatel, Kirsten and Shang, Runze and Yang, Yoon Mee and Xu, Meng and Zhang, Jie and Che, Li and Gordan, John and Cigliano, Antonio and Seki, Ekihiro and Evert, Matthias and Calvisi, Diego F. and Hu, Xiaosong and Chen, Xin (2019) MEK inhibition suppresses K-Ras wild-type cholangiocarcinoma in vitro and in vivo via inhibiting cell proliferation and modulating tumor microenvironment. CELL DEATH & DISEASE, 10: 120. ISSN 2041-4889

Xu, Meng and Wang, Jingxiao and Xu, Zhong and Li, Rong and Wang, Pan and Shang, Runze and Cigliano, Antonio and Ribback, Silvia and Solinas, Antonio and Pes, Giovanni Mario and Evert, Katja and Wang, Haichuan and Song, Xinhua and Zhang, Shu and Che, Li and Pascale, Rosa Maria and Calvisi, Diego Francesco and Liu, Qingguang and Chen, Xin (2019) SNAI1 Promotes the Cholangiocellular Phenotype, but not Epithelial-Mesenchymal Transition, in a Murine Hepatocellular Carcinoma Model. CANCER RESEARCH, 79 (21). pp. 5563-5574. ISSN 0008-5472, 1538-7445

Xu, Zhong and Xu, Meng and Liu, Pin and Zhang, Shu and Shang, Runze and Qiao, Yu and Che, Li and Ribback, Silvia and Cigliano, Antonio and Evert, Katja and Pascale, Rosa M. and Dombrowski, Frank and Evert, Matthias and Chen, Xi and Calvisi, Diego F. and Chen, Xin (2019) The mTORC2-Akt1 Cascade Is Crucial for c-Myc to Promote Hepatocarcinogenesis in Mice and Humans. HEPATOLOGY, 70 (5). pp. 1600-1613. ISSN 0270-9139, 1527-3350

Dong, Mingjie and Liu, Xianqiong and Evert, Katja and Utpatel, Kirsten and Peters, Michele and Zhang, Shanshan and Xu, Zhong and Che, Li and Cigliano, Antonio and Ribback, Silvia and Dombrowski, Frank and Cossu, Antonio and Gordan, John and Calvisi, Diego F. and Evert, Matthias and Liu, Yan and Chen, Xin (2018) Efficacy of MEK inhibition in a K-Ras-driven cholangiocarcinoma preclinical model. CELL DEATH & DISEASE, 9: 31. ISSN 2041-4889

Cigliano, Antonio and Wang, Chunmei and Pilo, Maria G. and Szydlowska, Marta and Brozzetti, Stefania and Latte, Gavinella and Pes, Giovanni M. and Pascale, Rosa M. and Seddaiu, Maria A. and Vidili, Gianpaolo and Ribback, Silvia and Dombrowski, Frank and Evert, Matthias and Chen, Xin and Calvisi, Diego F. (2017) Inhibition of HSF1 suppresses the growth of hepatocarcinoma cell lines in vitro and AKT-driven hepatocarcinogenesis in mice. ONCOTARGET, 8 (33). pp. 54149-54159. ISSN 1949-2553

Che, Li and Pilo, Maria G. and Cigliano, Antonio and Latte, Gavinella and Simile, Maria M. and Ribback, Silvia and Dombrowski, Frank and Evert, Matthias and Chen, Xin and Calvisi, Diego F. (2017) Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma. CELL CYCLE, 16 (6). pp. 499-507. ISSN 1538-4101, 1551-4005

Zhang, Shanshan and Song, Xinhua and Cao, Dan and Xu, Zhong and Fan, Biao and Che, Li and Hu, Junjie and Chen, Bin and Dong, Mingjie and Pilo, Maria G. and Cigliano, Antonio and Evert, Katja and Ribback, Silvia and Dombrowski, Frank and Pascale, Rosa M. and Cossu, Antonio and Vidili, Gianpaolo and Porcu, Alberto and Simile, Maria M. and Pes, Giovanni M. and Giannelli, Gianluigi and Gordan, John and Wei, Lixin and Evert, Matthias and Cong, Wenming and Calvisi, Diego F. and Chen, Xin (2017) Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice. JOURNAL OF HEPATOLOGY, 67 (6). pp. 1194-1203. ISSN 0168-8278, 1600-0641

Hu, Junjie and Che, Li and Li, Lei and Pilo, Maria G. and Cigliano, Antonio and Ribback, Silvia and Li, Xiaolei and Latte, Gavinella and Mela, Marta and Evert, Matthias and Dombrowski, Frank and Zheng, Guohua and Chen, Xin and Calvisi, Diego F. (2016) Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice. SCIENTIFIC REPORTS, 6: 20484. ISSN 2045-2322

Ribback, Silvia and Sailer, Verena and Boehning, Enrico and Guenther, Julia and Merz, Jaqueline and Steinmueller, Frauke and Utpatel, Kirsten and Cigliano, Antonio and Peters, Kristin and Pilo, Maria G. and Evert, Matthias and Calvisi, Diego F. and Dombrowski, Frank (2016) The Epidermal Growth Factor Receptor (EGFR) Inhibitor Gefitinib Reduces but Does Not Prevent Tumorigenesis in Chemical and Hormonal Induced Hepatocarcinogenesis Rat Models. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 17 (10): 1618. ISSN 1422-0067

Other

Chen, Li and Paliogiannis, Panagiotis and Cigliano, Antonio and Pito, Maria G. and Chen, Xin and Calvisi, Diego F. (2019) Pathogenetic, Prognostic, and Therapeutic Role of Fatty Acid Synthase in Human Hepatocellular Carcinoma. FRONTIERS MEDIA SA, LAUSANNE.

Wang, Jingxiao and Wang, Haichuan and Peters, Michele and Ding, Ning and Ribback, Silvia and Utpatel, Kirsten and Evert, Matthias and Cigliano, Antonio and Dombrowski, Frank and Song, Xinhua and Cossu, Antonio and Xu, Meng and Che, Li and Gordan, John Dozier and Calvisi, Diego and Chen, Xin (2019) A novel preclinical model of cholangiocarcinoma based on human aberrant FBXW7 expression. AMER SOC CLINICAL ONCOLOGY, ALEXANDRIA.