Items where Author is "Darras, Fouad H."

Article

Sadek, Bassem and Khan, Nadia and Darras, Fouad H. and Pockes, Steffen and Decker, Michael (2016) The dual-acting AChE inhibitor and H-3 receptor antagonist UW-MD-72 reverses amnesia induced by scopolamine or dizocilpine in passive avoidance paradigm in rats. PHYSIOLOGY & BEHAVIOR, 165. pp. 383-391. ISSN 0031-9384

Khan, Nadia and Saad, Ali and Nurulain, Syed M. and Darras, Fouad H. and Decker, Michael and Sadek, Bassem (2016) The dual-acting H3 receptor antagonist and AChE inhibitor UW-MD-71 dose-dependently enhances memory retrieval and reverses dizocilpine-induced memory impairment in rats. BEHAVIOURAL BRAIN RESEARCH, 297. pp. 155-164. ISSN 0166-4328, 1872-7549

Darras, Fouad H. and Wehle, Sarah and Huang, Guozheng and Sotriffer, Christoph A. and Decker, Michael (2014) Amine substitution of quinazolinones leads to selective nanomolar AChE inhibitors with 'inverted' binding mode. BIOORGANIC & MEDICINAL CHEMISTRY, 22 (17). pp. 4867-4881. ISSN 0968-0896, 1464-3391

Darras, Fouad H. and Kling, Beata and Sawatzky, Edgar and Heilmann, Joerg and Decker, Michael (2014) Cyclic acyl guanidines bearing carbamate moieties allow potent and dirigible cholinesterase inhibition of either acetyl- or butyrylcholinesterase. BIOORGANIC & MEDICINAL CHEMISTRY, 22 (17). pp. 5020-5034. ISSN 0968-0896, 1464-3391

Huang, Guozheng and Kling, Beata and Darras, Fouad H. and Hellmann, Joerg and Decker, Michael (2014) Identification of a neuroprotective and selective butyrylcholinesterase inhibitor derived from the natural alkaloid evodiamine. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 81. pp. 15-21. ISSN 0223-5234, 1768-3254

Nimczick, Martin and Pemp, Daniela and Darras, Fouad H. and Chen, Xinyu and Heilmann, Joerg and Decker, Michael (2014) Synthesis and biological evaluation of bivalent cannabinoid receptor ligands based on hCCB(2)R selective benzimidazoles reveal unexpected intrinsic properties. BIOORGANIC & MEDICINAL CHEMISTRY, 22 (15). pp. 3938-3946. ISSN 0968-0896, 1464-3391

Darras, Fouad H. and Pockes, Steffen and Huang, Guozhenz and Wehle, Sarah and Strasser, Andrea and Wittmann, Hans-Joachim and Nimczick, Martin and Sotriffer, Christoph A. and Decker, Michael (2014) Synthesis, Biological Evaluation, and Computational Studies of Tri- and Tetracyclic Nitrogen-Bridgehead Compounds as Potent Dual-Acting AChE Inhibitors and hH(3) Receptor Antagonists. ACS CHEMICAL NEUROSCIENCE, 5 (3). pp. 225-242. ISSN 1948-7193

Darras, Fouad H. and Kling, Beata and Heilmann, Joerg and Decker, Michael (2012) Neuroprotective Tri- and Tetracyclic BChE Inhibitors Releasing Reversible Inhibitors upon Carbamate Transfer. ACS MEDICINAL CHEMISTRY LETTERS, 3 (11). pp. 914-919. ISSN 1948-5875