Items where Author is "Thomas, Simone"

Article

Hammon, Kathrin and Renner, Kathrin and Althammer, Michael and Voll, Florian and Babl, Nathalie and Decking, Sonja-Maria and Siska, Peter J. and Matos, Carina and Conejo, Zugey Elizabeth Cardenas and Mendes, Karina and Einwag, Friederike and Siegmund, Heiko and Iberl, Sabine and Berger, Raffaela S. and Dettmer, Katja and Schoenmehl, Rebecca and Brochhausen, Christoph and Herr, Wolfgang and Oefner, Peter J. and Rehli, Michael and Thomas, Simone and Kreutz, Marina (2024) D-2-hydroxyglutarate supports a tolerogenic phenotype with lowered major histocompatibility class II expression in non-malignant dendritic cells and acute myeloid leukemia cells. HAEMATOLOGICA, 109 (8). pp. 2500-2514. ISSN 0390-6078, 1592-8721

Heudobler, Daniel and Lueke, Florian and Hahn, Joachim and Grube, Matthias and Schlosser, Pavla and Kremers, Stephan and Suedhoff, Thomas and Westermann, Joerg and Huetter-Kroenke, Marie Luise and Schlenk, Richard F. and Weber, Daniela and Paschka, Peter and Zeman, Florian and Doehner, Hartmut and Herr, Wolfgang and Reichle, Albrecht and Thomas, Simone (2024) Low-dose azacitidine, pioglitazone and all-trans retinoic acid is safe in patients aged ≥60 years with acute myeloid leukemia refractory to standard induction chemotherapy (AMLSG 26-16/AML-ViVA): results of the safety run-in phase. HAEMATOLOGICA, 109 (4). pp. 1274-1278. ISSN 0390-6078, 1592-8721

Thomas, Simone and Abken, Hinrich (2023) CAR T cell therapy becomes CHIC: "cytokine help intensified CAR" T cells. FRONTIERS IN IMMUNOLOGY, 13: 1090959. ISSN 1664-3224,

Dreger, Peter and Holtick, Udo and Subklewe, Marion and von Tresckow, Bastian and Ayuk, Francis and Wagner, Eva and Wulf, Gerald and Marks, Reinhardt and Penack, Olaf and Schnetzke, Ulf and Koenecke, Christian and von Bonin, Malte and Stelljes, Matthias and Glass, Bertram and Baldus, Claudia D. and Vucinic, Vladan and Mougiakakos, Dimitrios and Topp, Max and Schroers, Roland and Wolff, Daniel and Thomas, Simone and Kroeger, Nicolaus and Bethge, Wolfgang A. (2023) Impact of age on outcome of CAR-T cell therapies for large B-cell lymphoma: the GLA/DRST experience. BONE MARROW TRANSPLANTATION, 58. pp. 229-232. ISSN 0268-3369, 1476-5365

Harrer, Dennis Christoph and Heidenreich, Martin and Fante, Matthias Alexander and Mueller, Viktoria and Haehnel, Viola and Offner, Robert and Burkhardt, Ralph and Herr, Wolfgang and Edinger, Matthias and Wolff, Daniel and Thomas, Simone and Brosig, Andreas (2022) Apheresis for chimeric antigen receptor T-cell production in adult lymphoma patients. TRANSFUSION, 62 (8). pp. 1602-1611. ISSN 0041-1132, 1537-2995

Krauter, Steffi and Buescher, Nicole and Braeuchle, Eric and Ortega Iannazzo, Samira and Penner, Inessa and Kraemer, Nadine and Gogesch, Patricia and Thomas, Simone and Kreutz, Marina and Dejung, Mario and Freiwald, Anja and Butter, Falk and Waibler, Zoe and Plachter, Bodo (2022) An Attenuated Strain of Human Cytomegalovirus for the Establishment of a Subviral Particle Vaccine. VACCINES, 10 (8): 1326. ISSN , 2076-393X

Bethge, Wolfgang A. and Martus, Peter and Schmitt, Michael and Holtick, Udo and Subklewe, Marion and von Tresckow, Bastian and Ayuk, Francis and Wagner-Drouet, Eva Marie and Wulf, Gerald G. and Marks, Reinhard and Penack, Olaf and Schnetzke, Ulf and Koenecke, Christian and von Bonin, Malte and Stelljes, Matthias and Glass, Bertram and Baldus, Claudia D. and Vucinic, Vladan and Mougiakakos, Dimitrios and Topp, Max and Fante, Matthias A. and Schroers, Roland and Bayir, Lale and Borchmann, Peter and Buecklein, Veit and Hasenkamp, Justin and Hanoun, Christine and Thomas, Simone and Beelen, Dietrich W. and Lengerke, Claudia and Kroeger, Nicolaus and Dreger, Peter (2022) GLA/DRST real-world outcome analysis of CAR T-cell therapies for large B-cell lymphoma in Germany. BLOOD, 140 (4). pp. 349-358. ISSN 0006-4971, 1528-0020

Decking, Sonja-Maria and Bruss, Christina and Babl, Nathalie and Bittner, Sebastian and Klobuch, Sebastian and Thomas, Simone and Feuerer, Markus and Hoffmann, Petra and Dettmer, Katja and Oefner, Peter J. and Renner, Kathrin and Kreutz, Marina (2022) LDHB Overexpression Can Partially Overcome T Cell Inhibition by Lactic Acid. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23 (11): 5970. ISSN , 1422-0067

Berger, Raffaela S. and Wachsmuth, Christian J. and Waldhier, Magdalena C. and Renner-Sattler, Kathrin and Thomas, Simone and Chaturvedi, Anuhar and Niller, Hans-Helmut and Bumes, Elisabeth and Hau, Peter and Proescholdt, Martin and Gronwald, Wolfram and Heuser, Michael and Kreutz, Marina and Oefner, Peter J. and Dettmer, Katja (2021) Lactonization of the Oncometabolite D-2-Hydroxyglutarate Produces a Novel Endogenous Metabolite. CANCERS, 13 (8): 1756. ISSN , 2072-6694

Jetani, Hardikkumar and Navarro-Bailon, Almudena and Maucher, Marius and Frenz, Silke and Verbruggen, Christina and Yeguas, Ana and Vidriales, Maria Belen and Gonzalez, Marcos and Saborido, Judit Rial and Kraus, Sabrina and Mestermann, Katrin and Thomas, Simone and Bonig, Halvard and Luu, Maik and Monjezi, Razieh and Mougiakakos, Dimitrios and Sauer, Markus and Einsele, Hermann and Hudecek, Michael (2021) Siglec-6 is a novel target for CAR T-cell therapy in acute myeloid leukemia. BLOOD, 138 (19). pp. 1830-1842. ISSN 0006-4971, 1528-0020

Heudobler, Daniel and Herr, Wolfgang and Thomas, Simone (2019) Immunotherapies in hematology and oncology. ONKOLOGE, 25. pp. 77-82. ISSN 0947-8965, 1433-0415

Klobuch, Sebastian and Steinberg, Tim and Bruni, Emanuele and Mirbeth, Carina and Heilmeier, Bernhard and Ghibelli, Lina and Herr, Wolfgang and Reichle, Albrecht and Thomas, Simone (2018) Biomodulatory Treatment With Azacitidine, All-trans Retinoic Acid and Pioglitazone Induces Differentiation of Primary AML Blasts Into Neutrophil Like Cells Capable of ROS Production and Phagocytosis. FRONTIERS IN PHARMACOLOGY, 9: 1380. ISSN 1663-9812

Jetani, Hardikkumar and Garcia-Cadenas, Irene and Nerreter, Thomas and Thomas, Simone and Rydzek, Julian and Briones Meijide, Javier and Bonig, Halvard and Herr, Wolfgang and Sierra, Jordi and Einsele, Hermann and Hudecek, Michael (2018) CAR T-cells targeting FLT3 have potent activity against FLT3(-)ITD(+) AML and act synergistically with the FLT3-inhibitor crenolanib. LEUKEMIA, 32 (5). pp. 1168-1179. ISSN 0887-6924, 1476-5551

Renner, Kathrin and Seilbeck, Anton and Kauer, Nathalie and Ugele, Ines and Siska, Peter J. and Brummer, Christina and Bruss, Christina and Decking, Sonja-Maria and Fante, Matthias and Schmidt, Astrid and Hammon, Kathrin and Singer, Katrin and Klobuch, Sebastian and Thomas, Simone and Gottfried, Eva and Peter, Katrin and Kreutz, Marina (2018) Combined Metabolic Targeting With Metformin and the NSAIDs Diflunisal and Diclofenac Induces Apoptosis in Acute Myeloid Leukemia Cells. FRONTIERS IN PHARMACOLOGY, 9: 1258. ISSN 1663-9812

Heudobler, Daniel and Klobuch, Sebastian and Thomas, Simone and Hahn, Joachim and Herr, Wolfgang and Reichle, Albrecht (2018) Cutaneous Leukemic Infiltrates Successfully Treated With Biomodulatory Therapy in a Rare Case of Therapy-Related High Risk MDS/AML. FRONTIERS IN PHARMACOLOGY, 9: 1279. ISSN 1663-9812

Boettcher, Martin and Renner, Kathrin and Berger, Raffaela and Mentz, Kristin and Thomas, Simone and Cardenas-Conejo, Zugey Elizabeth and Dettmer, Katja and Oefner, Peter J. and Mackensen, Andreas and Kreutz, Marina and Mougiakakos, Dimitrios (2018) D-2-hydroxyglutarate interferes with HIF-1 stability skewing T-cell metabolism towards oxidative phosphorylation and impairing Th17 polarization. ONCOIMMUNOLOGY, 7 (7): e1445454. ISSN 2162-402X

Kiener, Richard and Fleischmann, Markus and Wiegand, Marian Alexander and Lemmermann, Niels A. W. and Schwegler, Christiane and Kaufmann, Christine and Renzaho, Angelique and Thomas, Simone and Felder, Eva and Niller, Hans Helmut and Asbach, Benedikt and Wagner, Ralf (2018) Efficient Delivery of Human Cytomegalovirus T Cell Antigens by Attenuated Sendai Virus Vectors. JOURNAL OF VIROLOGY, 92 (15): UNSP e0056. ISSN 0022-538X, 1098-5514

Vatter, Sarah and Schmid, Maximilian and Gebhard, Claudia and Mirbeth, Carina and Klobuch, Sebastian and Rehli, Michael and Herr, Wolfgang and Thomas, Simone (2018) In-vitro blockade of the CD4 receptor co-signal in antigen-specific T-cell stimulation cultures induces the outgrowth of potent CD4 independent T-cell effectors. JOURNAL OF IMMUNOLOGICAL METHODS, 454. pp. 80-85. ISSN 0022-1759, 1872-7905

Mathew, Nimitha R. and Baumgartner, Francis and Braun, Lukas and O'Sullivan, David and Thomas, Simone and Waterhouse, Miguel and Mueller, Tony A. and Hanke, Kathrin and Taromi, Sanaz and Apostolova, Petya and Illert, Anna L. and Melchinger, Wolfgang and Duquesne, Sandra and Schmitt-Graeff, Annette and Osswald, Lena and Yan, Kai-Li and Weber, Arnim and Tugues, Sonia and Spath, Sabine and Pfeifer, Dietmar and Follo, Marie and Claus, Rainer and Luebbert, Michael and Rummelt, Christoph and Bertz, Hartmut and Waesch, Ralph and Haag, Johanna and Schmidts, Andrea and Schultheiss, Michael and Bettinger, Dominik and Thimme, Robert and Ullrich, Evelyn and Tanriver, Yakup and Vuong, Giang Lam and Arnold, Renate and Hemmati, Philipp and Wolf, Dominik and Ditschkowski, Markus and Jilg, Cordula and Wilhelm, Konrad and Leiber, Christian and Gerull, Sabine and Halter, Joerg and Lengerke, Claudia and Pabst, Thomas and Schroeder, Thomas and Kobbe, Guido and Roesler, Wolf and Doostkam, Soroush and Meckel, Stephan and Stabla, Kathleen and Metzelder, Stephan K. and Halbach, Sebastian and Brummer, Tilman and Hu, Zehan and Dengjel, Joern and Hackanson, Bjoern and Schmid, Christoph and Holtick, Udo and Scheid, Christof and Spyridonidis, Alexandros and Stoelzel, Friedrich and Ordemann, Rainer and Mueller, Lutz P. and Sicre-de-Fontbrune, Flore and Ihorst, Gabriele and Kuball, Juergen and Ehlert, Jan E. and Feger, Daniel and Wagner, Eva-Maria and Cahn, Jean-Yves and Schnell, Jacqueline and Kuchenbauer, Florian and Bunjes, Donald and Chakraverty, Ronjon and Richardson, Simon and Gill, Saar and Kroeger, Nicolaus and Ayuk, Francis and Vago, Luca and Ciceri, Fabio and Mueller, Antonia M. and Kondo, Takeshi and Teshima, Takanori and Klaeger, Susan and Kuster, Bernhard and Kim, Dennis (Dong Hwan) and Weisdorf, Daniel and van der Velden, Walter and Doerfel, Daniela and Bethge, Wolfgang and Hilgendorf, Inken and Hochhaus, Andreas and Andrieux, Geoffroy and Boerries, Melanie and Busch, Hauke and Magenau, John and Reddy, Pavan and Labopin, Myriam and Antin, Joseph H. and Henden, Andrea S. and Hill, Geoffrey R. and Kennedy, Glen A. and Bar, Merav and Sarma, Anita and McLornan, Donal and Mufti, Ghulam and Oran, Betul and Rezvani, Katayoun and Shah, Omid and Negrin, Robert S. and Nagler, Arnon and Prinz, Marco and Burchert, Andreas and Neubauer, Andreas and Beelen, Dietrich and Mackensen, Andreas and von Bubnoff, Nikolas and Herr, Wolfgang and Becher, Burkhard and Socie, Gerard and Caligiuri, Michael A. and Ruggiero, Eliana and Bonini, Chiara and Haecker, Georg and Duyster, Justus and Finke, Juergen and Pearce, Erika and Blazar, Bruce R. and Zeiser, Robert (2018) Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells. NATURE MEDICINE, 24 (3). 282-+. ISSN 1078-8956, 1546-170X

Knies, Diana and Klobuch, Sebastian and Xue, Shao-An and Birtel, Matthias and Echchannaoui, Hakim and Yildiz, Oezlem and Omokoko, Tana and Guillaume, Philippe and Romero, Pedro and Stauss, Hans and Sahin, Ugur and Herr, Wolfgang and Theobald, Matthias and Thomas, Simone and Voss, Ralf-Holger (2016) An optimized single chain TCR scaffold relying on the assembly with the native CD3-complex prevents residual mispairing with endogenous TCRs in human T-cells. ONCOTARGET, 7 (16). pp. 21199-21221. ISSN 1949-2553

Thomas, Simone and Schelker, Roland and Klobuch, Sebastian and Zaiss, Sascha and Troppmann, Martina and Rehli, Michael and Haferlach, Torsten and Herr, Wolfgang and Reichle, Albrecht (2015) Biomodulatory therapy induces complete molecular remission in chemorefractory acute myeloid leukemia. HAEMATOLOGICA, 100 (1). E4-E6. ISSN 0390-6078

Thomas, Simone and Klobuch, Sebastian and Podlech, Juergen and Plachter, Bodo and Hoffmann, Petra and Renzaho, Angelique and Theobald, Matthias and Reddehase, Matthias J. and Herr, Wolfgang and Lemmermann, Niels A. W. (2015) Evaluating Human T-Cell Therapy of Cytomegalovirus Organ Disease in HLA-Transgenic Mice. PLOS PATHOGENS, 11 (7): e1005049. ISSN 1553-7366, 1553-7374

Zupke, Oliver and Distler, Eva and Juerchott, Anna and Paiphansiri, Umaporn and Dass, Martin and Thomas, Simone and Hartwig, Udo F. and Theobald, Matthias and Landfester, Katharina and Mailaender, Volker and Herr, Wolfgang (2015) Nanoparticles and antigen-specific T-cell therapeutics: a comprehensive study on uptake and release. NANOMEDICINE, 10 (7). pp. 1063-1076. ISSN 1743-5889, 1748-6963

Doerrie, Jan and Krug, Christian and Hofmann, Christian and Mueller, Ina and Wellner, Verena and Knippertz, Ilka and Schierer, Stephan and Thomas, Simone and Zipperer, Elke and Printz, Dieter and Fritsch, Gerhard and Schuler, Gerold and Schaft, Niels and Geyeregger, Rene (2014) Human Adenovirus-Specific gamma/delta and CD8(+) T Cells Generated by T-Cell Receptor Transfection to Treat Adenovirus Infection after Allogeneic Stem Cell Transplantation. PLOS ONE, 9 (10): e109944. ISSN 1932-6203

Thomas, Simone and Klobuch, Sebastian and Sommer, Maria and van Ewijk, Reyn and Theobald, Matthias and Meyer, Ralf G. and Herr, Wolfgang (2014) Human CD8(+) memory and EBV-specific T cells show low alloreactivity in vitro and in CD34(+) stem cell-engrafted NOD/SCID/IL-2R gamma c(null) mice. EXPERIMENTAL HEMATOLOGY, 42 (1). pp. 28-38. ISSN 0301-472X, 1873-2399

Conference or Workshop Item

Thomas, Simone and Wermke, Martin and Vucinic, Vladan and Wagner-Drouet, Eva and Mackensen, Andreas and Zeiser, Robert and Bug, Gesine and Schmitt, Michael and Prinz, Petra and Schendel, Dolores and Pinkernell, Kai and Goedkoop, Rene (2023) FIRST-IN-HUMAN STUDY OF MDG1011, A TCR-T CELL THERAPY DIRECTED AGAINST HLA-A*02:01-RESTRICTED PRAME, FOR HIGH-RISK MYELOID AND LYMPHOID NEOPLASMS (CD-TCR-001). In: 49th Annual Annual Meeting of the European Society for Blood and Marrow Transplantation, 23 - 26 April, 2023, Hybrid Meeting.

Thomas, Simone (2022) Bispecific Antibodies. In: Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien.

Other

Bishop, Michael and Flinn, Ian and Borchmann, Peter and Jaeger, Ulrich and Westin, Jason and Hamad, Nada and Purtill, Duncan and Greil, Richard and Thomas, Simone and Teshima, Takanori and Harigae, Hideo and Garcia, Carlos and Barba, Pere and Deol, Abhinav and Shaughnessy, Paul and Gu, Jessie and Andreola, Giovanna and Prieto, Marcela Martinez and Pacaud, Lida and Schuster, Stephen (2019) BELINDA : A phase 3 study evaluating the safety and efficacy of tisagenlecleucel versus standard of care in adult patients with relapsed/refractory aggressive B-cell non-Hodgkin lymphoma. BMC, LONDON.

Klobuch, Sebastian and Neidlinger, Elisabeth and Mirbeth, Carina and Herr, Wolfgang and Thomas, Simone (2019) Characterization of an HLA-DPB1 specific T-cell receptor for adoptive immunotherapy. NATURE PUBLISHING GROUP, LONDON.

Heudobler, Daniel and Rechenmacher, Michael and Lueke, Florian and Vogelhuber, Martin and Klobuch, Sebastian and Thomas, Simone and Pukrop, Tobias and Hackl, Christina and Herr, Wolfgang and Ghibelli, Lina and Gerner, Christopher and Reichle, Albrecht (2018) Clinical Efficacy of a Novel Therapeutic Principle, Anakoinosis. FRONTIERS MEDIA SA, LAUSANNE.

Thomas, Simone and Lemmermann, Niels and Klobuch, Sebastian and Podlech, Juergen and Theobald, Matthias and Reddehase, Matthias J. and Herr, Wolfgang (2014) Adoptive Transfer of T-Cell-Receptor Engineered Human T Cells Specifically Reduces Viral Titers in HLA-Transgenic NSG Mice Infected with a Humanized Cytomegalovirus. AMER SOC HEMATOLOGY, WASHINGTON.