Items where Division is "Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)" and Year is 2019

A

Agnetta, Luca and Bermudez, Marcel and Riefolo, Fabio and Matera, Carlo and Claro, Enrique and Messerer, Regina and Littmann, Timo and Wolber, Gerhard and Holzgrabe, Ulrike and Decker, Michael (2019) Fluorination of Photoswitchable Muscarinic Agonists Tunes Receptor Pharmacology and Photochromic Properties. JOURNAL OF MEDICINAL CHEMISTRY, 62 (6). pp. 3009-3020. ISSN 0022-2623, 1520-4804

Andreev, Stanislav and Pantsar, Tatu and Ansideri, Francesco and Kudolo, Mark and Forster, Michael and Schollmeyer, Dieter and Laufer, Stefan A. and Koch, Pierre (2019) Design, Synthesis and Biological Evaluation of 7-Chloro-9H-pyrimido[4,5-b]indole-based Glycogen Synthase Kinase-3 beta Inhibitors. MOLECULES, 24 (12): 2331. ISSN 1420-3049

B

Bartole, Edith and Littmann, Timo and Tanaka, Miho and Ozawa, Takeaki and Buschauer, Armin and Bernhardt, Guenther (2019) [H-3]UR-DEBa176: A 2,4-Diaminopyrimidine-Type Radioligand Enabling Binding Studies at the Human, Mouse, and Rat Histamine H-4 Receptors. JOURNAL OF MEDICINAL CHEMISTRY, 62 (17). pp. 8338-8356. ISSN 0022-2623, 1520-4804

F

Forster, L. and Buschauer, A. and Bernhardt, G. (2019) Investigation of GPCR-beta-arrestin interactions using a split-luciferase complementation assay: Application to the D-2long and D-3 receptor. SPRINGER, NEW YORK.

G

Gergs, U. and Bernhardt, G. and Buchwalow, I. B. and Edler, H. and Froeba, J. and Keller, M. and Kirchhefer, U. and Koehler, F. and Misslinger, N. and Wache, H. and Neumann, J. (2019) Initial Characterization of Transgenic Mice Overexpressing Human Histamine H-2 Receptors. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 369 (1). pp. 129-141. ISSN 0022-3565, 1521-0103

Graetz, L. and Littmann, T. and Bartole, E. and Biselli, S. and Pegoli, A. and Keller, M. and Buschauer, A. and Bernhardt, G. (2019) A BRET-based assay to determine the binding of ligands to GPCRs using pyrylium-labeled fluorescent tracers. SPRINGER, NEW YORK.

Graetz, L. and Littmann, T. and Bartole, E. and Biselli, S. and Tropmann, K. and Keller, M. and Buschauer, A. and Bernhardt, G. (2019) BRET-BASED BINDING ASSAYS: PYRYLIUM-LABELED HISTAMINE RECEPTOR LIGANDS ALLOW FOR THE DETERMINATION OF BINDING CONSTANTS AT EQUILIBRIUM AND IN REAL TIME. SPRINGER BASEL AG, BASEL.

H

Heider, Fabian and Ansideri, Francesco and Tesch, Roberta and Pantsar, Tatu and Haun, Urs and Doering, Eva and Kudolo, Mark and Poso, Antti and Albrecht, Wolfgang and Laufer, Stefan A. and Koch, Pierre (2019) Pyridinylimidazoles as dual glycogen synthase kinase 3 beta/p38 alpha mitogen-activated protein kinase inhibitors. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 175. pp. 309-329. ISSN 0223-5234, 1768-3254

Heider, Fabian and Pantsar, Tatu and Kudolo, Mark and Ansideri, Francesco and De Simone, Angela and Pruccoli, Letizia and Schneider, Taiane and Goettert, Marcia Ines and Tarozzi, Andrea and Andrisano, Vincenza and Laufer, Stefan A. and Koch, Pierre (2019) Pyridinylimidazoles as GSK3 beta Inhibitors: The Impact of Tautomerism on Compound Activity via Water Networks. ACS MEDICINAL CHEMISTRY LETTERS, 10 (10). pp. 1407-1414. ISSN 1948-5875

Hoering, C. and Graetz, L. and Littmann, T. and Buschauer, A. and Bernhardt, G. and Strasser, A. (2019) Mini G protein recruitment as an approach to the functional characterization of histamine receptor ligands. SPRINGER, NEW YORK.

Hoering, C. and Graetz, L. and Strasser, A. and Bernhardt, G. (2019) A MINI-G PROTEIN RECRUITMENT ASSAY FOR THE HUMAN HISTAMINE H-4 RECEPTOR. SPRINGER BASEL AG, BASEL.

I

Ibrahim, Passainte and Wifling, David and Clark, Timothy (2019) Universal Activation Index for Class A GPCRs. JOURNAL OF CHEMICAL INFORMATION AND MODELING, 59 (9). pp. 3938-3945. ISSN 1549-9596, 1549-960X

L

Lazewska, Dorota and Mogilski, Szczepan and Hagenow, Stefanie and Kuder, Kamil and Gluch-Lutwin, Monika and Siwek, Agata and Wiecek, Malgorzata and Kaleta, Maria and Seibel, Ulla and Buschauer, Armin and Filipek, Barbara and Stark, Holger and Kiec-Kononowicz, Katarzyna (2019) Alkyl derivatives of 1,3,5-triazine as histamine H-4 receptor ligands. BIOORGANIC & MEDICINAL CHEMISTRY, 27 (7). pp. 1254-1262. ISSN 0968-0896, 1464-3391

Littmann, Timo and Buschauer, Armin and Bernhardt, Gunther (2019) Split luciferase-based assay for simultaneous analyses of the ligand concentration- and time-dependent recruitment of beta-arrestin2. ANALYTICAL BIOCHEMISTRY, 573. pp. 8-16. ISSN 0003-2697, 1096-0309

M

Maschauer, Simone and Ott, Julian J. and Bernhardt, Guenther and Kuwert, Torsten and Keller, Max and Prante, Olaf (2019) F-18-labelled triazolyl-linked argininamides targeting the neuropeptideYY(1)R for PET imaging of mammary carcinoma. SCIENTIFIC REPORTS, 9: 12990. ISSN 2045-2322

P

Pegoli, Andrea and Wifling, David and Gruber, Corinna G. and She, Xueke and Huebner, Harald and Bernhardt, Guenther and Gmeiner, Peter and Keller, Max (2019) Conjugation of Short Peptides to Dibenzodiazepinone-Type Muscarinic Acetylcholine Receptor Ligands Determines M2R Selectivity. JOURNAL OF MEDICINAL CHEMISTRY, 62 (11). pp. 5358-5369. ISSN 0022-2623, 1520-4804

S

Scharrenbroich, Jessica and Kaever, Volkhard and Dove, Stefan and Seifert, Roland and Schneider, Erich H. (2019) Hydrolysis of the non-canonical cyclic nucleotide cUMP by PDE9A: kinetics and binding mode. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 392 (2). pp. 199-208. ISSN 0028-1298, 1432-1912

Schindler, Lisa and Bernhardt, Guenther and Keller, Max (2019) Modifications at Arg and Ile Give Neurotensin(8-13) Derivatives with High Stability and Retained NTS1 Receptor Affinity. ACS MEDICINAL CHEMISTRY LETTERS, 10 (6). pp. 960-965. ISSN 1948-5875

Schramm, Simon and Agnetta, Luca and Bermudez, Marcel and Gerwe, Hubert and Irmen, Matthias and Holze, Janine and Littmann, Timo and Wolber, Gerhard and Traenkle, Christian and Decker, Michael (2019) Novel BQCA- and TBPB-Derived M-1 Receptor Hybrid Ligands: Orthosteric Carbachol Differentially Regulates Partial Agonism. CHEMMEDCHEM, 14 (14). pp. 1349-1358. ISSN 1860-7179, 1860-7187

Seibel, U. and Buschauer, A. and Bernhardt, G. and Strasser, A. (2019) A DYNAMIC MASS REDISTRIBUTION ASSAY FOR THE HISTAMINE H-4 RECEPTOR. SPRINGER BASEL AG, BASEL.

Seibel, U. and Buschauer, A. and Bernhardt, G. and Strasser, A. (2019) Dynamic mass redistribution analysis of histamine H4 receptor ligands in HEK293T cells. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 392 (1Suppl). S27-S28. ISSN 0028-1298, 1432-1912

Stolwijk, J. A. and Skiba, M. and Kade, C. and Bernhardt, G. and Buschauer, A. and Huebner, H. and Gmeiner, P. and Wegener, J. (2019) Increasing the throughput of label-free cell assays to study the activation of G-protein-coupled receptors by using a serial agonist exposure protocol. INTEGRATIVE BIOLOGY, 11 (3). pp. 99-108. ISSN 1757-9694, 1757-9708

W

Wifling, David and Pfleger, Christopher and Kaindl, Jonas and Ibrahim, Passainte and Kling, Ralf C. and Buschauert, Armin and Gohlke, Holger and Clark, Timothy (2019) Basal Histamine H-4 Receptor Activation: Agonist Mimicry by the Diphenylalanine Motif. CHEMISTRY-A EUROPEAN JOURNAL, 25 (64). pp. 14613-14624. ISSN 0947-6539, 1521-3765