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B

Bogdahn, U. and Hau, P. and Brawanski, A. and Schlaier, J. and Mehdorn, M. and Wurm, G. and Pichler, J. and Kunst, M. and Stauder, G. and Schlingensiepen, K. H. (2004) Specific therapy for high-grade glioma by convection-enhanced delivery of the TGF-beta 2 specific antisense oligonucleotide AP 12009. In: 40th Annual Meeting of the American Society of Clinical Oncology, June 05-08, 2004, New Orleans, LA.

Bogdahn, U. and Hau, P. and Olyushin, V. and Mahapatra, A. K. and Parfenov, V. and Venkataramana, N. K. and Wassmann, H. and Ludwig, S. and Heinrichs, H. and Schlingensiepen, K. H. (2008) Targeted therapy with AP 12009 in recurrent or refractory glioblastoma patients: Results of a phase lib study. JOURNAL OF CLINICAL ONCOLOGY, 26 (15supp): 2018. ISSN 0732-183X

Bogdahn, U. and Mahapatra, A. and Olyushin, V. E. and Mouli, C. and Parfenov, V. E. and Stockhammer, G. and Ludwig, S. and Wuerth, G. and Heinrichs, H. and Schlingensiepen, K. (2007) A phase IIb actively controlled study with the TGF-beta-2 inhibitor AP 12009 for recurrent or refractory anaplastic astrocytoma. JOURNAL OF CLINICAL ONCOLOGY, 25 (18supp): 2025. ISSN 0732-183X, 1527-7755

Bogdahn, U. and Mahapatra, A. K. and Olyushin, V. and Parfenov, V. and Stockhammer, G. and Ludwig, S. and Wuerth, G. and Heinrichs, H. and Schlingensiepen, K. H. (2008) Results of a phase lib active-controlled study with AP 12009 for patients with recurrent or refractory anaplastic astrocytoma. JOURNAL OF CLINICAL ONCOLOGY, 26 (15supp): 2076. ISSN 0732-183X

Bogdahn, U. and Oliushine, V. E. and Parfenov, V. E. and Kunst, M. and Mahapatra, A. and Sastry, K. V. and Venkataramana, K. N. and Jachimczak, P. and Hau, P. and Schlingensiepen, K. (2006) Results of G004, a phase IIb study in recurrent glioblastoma patients with the TGF-b2 targeted compound AP 12009. JOURNAL OF CLINICAL ONCOLOGY, 24 (18Supp). 71S. ISSN 0732-183X

Bogdahn, U. and Stockhammer, G. and Mahapatra, A. K. and Venkataramana, N. K. and Oliushine, V. E. and Partenov, V. E. and Poverennova, I. E. and Jachimczak, P. and Heinrichs, H. and Schlingensiepen, K. (2010) Pseudoprogression after treatment with the TGF-beta 2 inhibitor trabedersen in high-grade glioma patients. JOURNAL OF CLINICAL ONCOLOGY, 28 (15supp). ISSN 0732-183X, 1527-7755

Brandes, A. A. and Stupp, R. and Hau, P. and Sleijfer, S. and Lacombe, D. and Gorlia, T. and Yun, H. and Tosoni, A. and Mirimanoff, R. and van den Bent, M. J. (2007) EORTC Study 26041-22041: Phase I/II study on concomitant and adjuvant temozolomide (TMZ) and radiotherapy (RT) with or without PTK787/ZK222584 (PTK/ZK) in newly diagnosed glioblastoma-Results of a phase I trial. JOURNAL OF CLINICAL ONCOLOGY, 25 (18supp): 2026. ISSN 0732-183X, 1527-7755

D

Dresemann, G. and Hosius, C. and Lilienthal, J. and Schleyer, E. and Bogdan, U. and Weller, M. and Paulus, W. (2008) Treatment failure due to intracerebral stem cell-like behavior of glioblastoma (GBM) cells: A reason for targeted maintenance therapy with imatinib (I) and hydroxyurea (H)? An analysis of study DE21 and DE40 (Ambrosia). JOURNAL OF CLINICAL ONCOLOGY, 26 (15supp): 2048. ISSN 0732-183X

G

Glas, M. and Koch, H. and Hirschmann, B. and Jauch, T. and Steinbrecher, A. and Bogdahn, U. and Hau, P. (2007) Pegylated liposomal doxorubicin in recurrent high-grade glioma: Comparison of clinical trial results and compassionate use. JOURNAL OF CLINICAL ONCOLOGY, 25 (18supp): 2073. ISSN 0732-183X, 1527-7755

H

Hau, P. and Bogdahn, U. and Olyushin, V. E. and Mahapatra, A. and Parfenov, V. E. and Venkataramana, K. and Ludwig, S. and Jachimczak, P. and Heinrichs, H. and Schlingensiepen, K. (2007) Results of a phase IIb study in recurrent or refractory glioblastoma patients with the TGF-beta-2 inhibitor AP 12009. JOURNAL OF CLINICAL ONCOLOGY, 25 (18supp): 12521. ISSN 0732-183X, 1527-7755

Hau, P. and Jauch, T. and Hirschmann, B. and Drechsel, E. and Grauer, O. and Koch, H. and Wismeth, C. and Steinbrecher, A. and Bogdahn, U. (2004) Adjuvant chemotherapy with temozolomide and pegylated liposomal doxorubicin in the first-line therapy of patients with glioblastoma - A phase-II trial. In: 40th Annual Meeting of the American Society of Clinical Oncology, June 05-08, 2004, New Orleans, LA.

Hau, P. and Kunst, M. and Pichler, J. and Parfenov, V. E. and Sastry, K. V. R. and Spitznagel, L. and Zaaroor, M. and Bogdahn, U. and Schlingensiepen, K. H. (2005) Targeted downregulation of TGF-beta2 as immunotherapy for high-grade glioma: A phase IIb study. In: 41st Annual Meeting of the American Society of Clinical Oncology, May 13-17, 2005, Orlando, Florida, USA.

Hau, P. and Stockhammer, G. and Kunst, M. and Mahapatra, A. and Sastry, K. V. and Parfenov, V. E. and Leshinsky, V. G. and Jachimczak, P. and Bogdahn, U. and Schlingensiepen, K. (2006) Results of G004, a phase IIb actively controlled clinical trial with the TGF-b2 targeted compound AP 12009 for recurrent anaplastic astrocytoma. JOURNAL OF CLINICAL ONCOLOGY, 24 (18Supp). 74S. ISSN 0732-183X

Herrlinger, Ulrich and Schaefer, Niklas and Steinbach, Joachim P. and Weyerbrock, Astrid and Hau, Peter and Goldbrunner, Roland and Friedrich, Franziska and Rohde, Veit and Ringel, Florian and Schlegel, Uwe and Sabel, Michael and Ronellenfitsch, Michael W. and Uhl, Martin and Maciaczyk, Jaroslaw and Grau, Stefan and Schnell, Oliver and Haenel, Mathias and Krex, Dietmar and Vajkoczy, Peter and Gerlach, Ruediger and Kortmann, Rolf-Dieter and Mehdorn, Maximilian and Tuettenberg, Jochen and Mayer-Steinacker, Regine and Fietkau, Rainer and Brehmer, Stefanie and Mack, Frederic and Stuplich, Moritz and Kebir, Sied and Kohnen, Ralf and Dunkl, Elmar and Leutgeb, Barbara and Proescholdt, Martin and Pietsch, Torsten and Urbach, Horst and Belka, Claus and Stummer, Walter and Glas, Martin (2016) Bevacizumab Plus Irinotecan Versus Temozolomide in Newly Diagnosed O-6-Methylguanine-DNA Methyltransferase Nonmethylated Glioblastoma: The Randomized GLARIUS Trial. JOURNAL OF CLINICAL ONCOLOGY, 34 (14). 1611-U134. ISSN 0732-183X, 1527-7755

Herrlinger, Ulrich and Schaefer, Niklas and Steinbach, Joachim Peter and Weyerbrock, Astrid and Hau, Peter and Goldbrunner, Roland and Friedrich, Franziska and Stockhammer, Florian and Ringel, Florian and Braun, Christian and Kohnen, Ralf and Leutgeb, Barbara and Belka, Claus and Urbach, Horst and Stummer, Walter and Glas, Martin (2013) Bevacizumab, irinotecan, and radiotherapy versus standard temozolomide and radiotherapy in newly diagnosed, MGMT-non-methylated glioblastoma patients: First results from the randomized multicenter GLARIUS trial. JOURNAL OF CLINICAL ONCOLOGY, 31 (15supp): LBA2000. ISSN 0732-183X, 1527-7755

Herrlinger, Ulrich and Schaefer, Niklas and Steinbach, Joachim Peter and Weyerbrock, Astrid and Hau, Peter and Goldbrunner, Roland and Friedrich, Franziska and Stockhammer, Florian and Ringel, Florian and Braun, Christian and Kohnen, Ralf and Leutgeb, Barbara and Belka, Claus and Urbach, Horst and Stummer, Walter and Glas, Martin (2013) Bevacizumab, irinotecan, and radiotherapy versus standard temozolomide and radiotherapy in newly diagnosed, MGMT-nonmethylated glioblastoma patients: First results from the randomized multicenter GLARIUS trial. JOURNAL OF CLINICAL ONCOLOGY, 31 (18supp): LBA2000. ISSN 0732-183X, 1527-7755

Herrlinger, Ulrich and Schaefer, Nildas and Steinbach, Joachim Peter and Weyerbrock, Astrid and Hau, Peter and Goldbrunner, Roland and Friedrich, Franziska and Rohde, Veit and Ringel, Florian and Braun, Christian and Kohnen, Ralf and Leutgeb, Barbara and Belka, Claus and Urbach, Horst and Stummer, Walter and Gies, Martin (2014) Survival and quality of life in the randomized, multicenter GLARIUS trial investigating bevacizumab/irinotecan versus standard temozolornide in newly diagnosed, MGMT-non-methylated glioblastoma patients. AMER SOC CLINICAL ONCOLOGY, ALEXANDRIA.

J

Jauch, T. and Hau, P. and Bogdahn, U. (2007) Re-challenge with temozolomide (TMZ) at recurrence in high-grade gliomas (HGG). JOURNAL OF CLINICAL ONCOLOGY, 25 (18supp): 2034. ISSN 0732-183X, 1527-7755

S

Schalke, B. (2010) Treatment of unresectable thymoma with neoadjuvant octreotide LAR. JOURNAL OF CLINICAL ONCOLOGY, 28 (15supp). ISSN 0732-183X, 1527-7755

Schalke, Berthold and Boy, Sandra and Hofmann, Hans-Stefan and Stroebel, Philipp and Marienhagen, Joerg and May, Christoph and Stuermer, Andrea and Marx, Alexander (2012) Neoadjuvant treatment of primary inoperable or local recurrent thymoma with octreotide LAR to improve tumor resectability. JOURNAL OF CLINICAL ONCOLOGY, 30 (15supp): 7105. ISSN 0732-183X, 1527-7755

Steinbrecher, A. and Beier, D. and Jauch, T. and Hau, P. and Baumgart, U. and Wismeth, C. and Bogdahn, U. (2005) Adjuvant chemotherapy with temozolomide and liposomal doxorubicin in the first-line therapy of patients with glioblastoma: A phase-II trial. In: 41st Annual Meeting of the American Society of Clinical Oncology, May 13-17, 2005, Orlando, Florida, USA.

Stroebel, Philipp and Bauer, Andrea and Puppe, Bernhard and Kraushaar, Til and Krein, Axel and Toyka, Klaus and Gold, Ralf and Semik, Michael and Kiefer, Reinhard and Nix, Wilfred and Schalke, Berthold and Mueller-Hermelink, Hans Konrad and Marx, Alexander (2004) Tumor recurrence and survival in patients treated for thymomas and thymic squamous cell carcinomas: A retrospective analysis. JOURNAL OF CLINICAL ONCOLOGY, 22 (8). pp. 1501-1509. ISSN 0732-183X, 1527-7755

Stupp, Roger and Hegi, Monika E. and Gorlia, Thierry and Erridge, Sara and Grujicic, Danica and Steinbach, Joachim Peter and Wick, Wolfgang and Tarnawski, Rafal and Nam, Do-Hyun and Weyerbrock, Astrid and Hau, Peter and Taphoorn, Martin J. B. and Nabors, Louis B. and Reardon, David A. and Van den Bent, Martin J. and Perry, James R. and Hong, Yong Kil and Hicking, Christine and Picard, Martin and Weller, Michael (2013) Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma and methylated O-6-methylguanine-DNA methyltransferase (MGMT) gene promoter: Key results of the multicenter, randomized, open-label, controlled, phase III CENTRIC study. AMER SOC CLINICAL ONCOLOGY, ALEXANDRIA.

T

Tabatabai, Ghazaleh and Wick, Wolfgang and Reifenberger, Guido and Steinbach, Joachim Peter and Schnell, Oliver and Hau, Peter and Herrlinger, Ulrich and Sabel, Michael and Ketter, Ralf and Schlegel, Uwe S. and Marosi, Christine and Goldbrunner, Roland and Homicsko, Krisztian and Nikkhah, Guido and Pichler, Josef and Vajkoczy, Peter and Meixensberger, Juergen and Weller, Michael (2013) Dose-intensified rechallenge with temozolomide: One week on/one week off versus 3 weeks on/one week off in patients with progressive or recurrent glioblastoma (DIRECTOR). JOURNAL OF CLINICAL ONCOLOGY, 31 (15supp): TPS2103. ISSN 0732-183X, 1527-7755

Tabatabal, Ghazaleh and Wick, Wolfgang and Steinbach, Joachim Peter and Wick, Antje and Schnell, Oliver and Hau, Peter and Herrlinger, Ulrich and Sabel, Michael and Wlrsching, Hans-Georg and Ketter, Ralf and Baehr, Oliver and Platten, Michael and Tonn, Joerg and Huesing, Johannes and Reifenberger, Guido and Weller, Michael (2014) MGMT promoter methylation as a prognostic biomarker for benefit front dose-intensified temozolomide rechallenge in progressive glioblastoma; First results from the randomized phase II DIRECTOR trial. AMER SOC CLINICAL ONCOLOGY, ALEXANDRIA.

W

Wick, Wolfgang and Roth, Patrick and Wiestler, Benedikt and Hartmann, Christian and Hau, Peter and Nakamura, Makoto and Stockhammer, Florian and Sabel, Michael and Koeppen, Susanne and Ketter, Ralf and Vajkoczy, Peter and Eyupoglus, Ilker and Kaendler, Stephen and Kalff, Rolf and Galldiks, Norbert and Schmidt-Graf, Friederike and von Deimling, Andreas and Platten, Michael and Reifenberger, Guido and Weller, Michael (2015) Long-term analysis of the NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with PCV or temozolomide. AMER SOC CLINICAL ONCOLOGY, ALEXANDRIA.