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D

Deml, Karl-Friedrich and Beermann, Silke and Neumann, Detlef and Strasser, Andrea and Seifert, Roland (2009) Interactions of Histamine H-1-Receptor Agonists and Antagonists with the Human Histamine H-4-Receptor. MOLECULAR PHARMACOLOGY, 76 (5). pp. 1019-1030. ISSN 0026-895X

G

Goettle, Martin and Dove, Stefan and Steindel, Phillip and Shen, Yuequan and Tang, Wei-Jen and Geduhn, Jens and Koenig, Burkhard and Seifert, Roland (2007) Molecular analysis of the interaction of Bordetella pertussis adenylyl cyclase with fluorescent Nucleotides. MOLECULAR PHARMACOLOGY, 72 (3). pp. 526-535. ISSN 0026-895X, 1521-0111

H

Huebner, Melanie and Dixit, Anshuman and Mou, Tung-Chung and Lushington, Gerald H. and Pinto, Cibele and Gille, Andreas and Geduhn, Jens and Koenig, Burkhard and Sprang, Stephen R. and Seifert, Roland (2011) Structural Basis for the High-Affinity Inhibition of Mammalian Membranous Adenylyl Cyclase by 2 ',3 '-O-(N-Methylanthraniloyl)-Inosine 5 '-Triphosphate. MOLECULAR PHARMACOLOGY, 80 (1). pp. 87-96. ISSN 0026-895X

K

Koehler, Jens and Kuehnel, Thomas and Kees, Frieder and Hoecherl, Klaus and Grobecker, Horst F. (2002) Comparison of bioavailability and metabolism with two commercial formulations of cyclosporine A in rats. DRUG METABOLISM AND DISPOSITION, 30 (6): UNSP 636/9. pp. 658-662. ISSN 0090-9556, 1521-009X

M

Mou, Tung-Chung and Gille, Andreas and Suryanarayana, Srividya and Richter, Mark and Seifert, Roland and Sprang, Stephen R. (2006) Broad specificity of mammalian adenylyl cyclase for interaction with 2 ',3 '-substituted purine- and pyrimidine nucleotide inhibitors. MOLECULAR PHARMACOLOGY, 70 (3). pp. 878-886. ISSN 0026-895X

P

Pinto, Cibele and Papa, Dan and Huebner, Melanie and Mou, Tung-Chung and Lushington, Gerald H. and Seifert, Roland (2008) Activation and inhibition of adenylyl cyclase isoforms by forskolin analogs. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 325 (1). pp. 27-36. ISSN 0022-3565

Preuss, Hendrik and Ghorai, Prasanta and Kraus, Anja and Dove, Stefan and Buschauer, Armin and Seifert, Roland (2007) Constitutive activity and ligand selectivity of human, guinea pig, rat, and canine histamine H-2 receptors. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 321 (3). pp. 983-995. ISSN 0022-3565

Preuss, Hendrik and Ghorai, Prasanta and Kraus, Anja and Dove, Stefan and Buschauer, Armin and Seifert, Roland (2007) Mutations of Cys-17 and Ala-271 in the human histamine H-2 receptor determine the species selectivity of guanidine-type agonists and increase constitutive activity. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 321 (3). pp. 975-982. ISSN 0022-3565

R

Rottlaender, Dennis and Matthes, Jan and Vatner, Stephen F. and Seifert, Roland and Herzig, Stefan (2007) Functional adenylyl cyclase inhibition in murine cardiomyocytes by 2 '(3 ')-O-(N-methylanthraniloyl)-guanosine 5 '-[gamma-thio]triphosphate. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 321 (2). pp. 608-615. ISSN 0022-3565

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Schneider, Erich H. and Strasser, Andrea and Thurmond, Robin L. and Seifert, Roland (2010) Structural Requirements for Inverse Agonism and Neutral Antagonism of Indole-, Benzimidazole-, and Thienopyrrole-Derived Histamine H-4 Receptor Ligands. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 334 (2). pp. 513-521. ISSN 0022-3565, 1521-0103

Schnell, David and Burleigh, Katrina and Trick, Jonathan and Seifert, Roland (2010) No Evidence for Functional Selectivity of Proxyfan at the Human Histamine H-3 Receptor Coupled to Defined G(i)/G(o) Protein Heterotrimers. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 332 (3). pp. 996-1005. ISSN 0022-3565

Seifert, Roland and Schneider, Erich H. and Dove, Stefan and Brunskole, Irena and Neumann, Detlef and Strasser, Andrea and Buschauer, Armin (2011) Paradoxical Stimulatory Effects of the "Standard" Histamine H-4-Receptor Antagonist JNJ7777120: the H-4 Receptor Joins the Club of 7 Transmembrane Domain Receptors Exhibiting Functional Selectivity. MOLECULAR PHARMACOLOGY, 79 (4). pp. 631-638. ISSN 0026-895X, 1521-0111

Strasser, Andrea and Wittmann, Hans-Joachim and Seifert, Roland (2008) Ligand-specific contribution of the N terminus and E2-loop to pharmacological properties of the histamine H(1)-receptor. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 326 (3). pp. 783-791. ISSN 0022-3565

Suryanarayana, Srividya and Goettle, Martin and Huebner, Melanie and Gille, Andreas and Mou, Tung-Chung and Sprang, Stephen R. and Richter, Mark and Seifert, Roland (2009) Differential Inhibition of Various Adenylyl Cyclase Isoforms and Soluble Guanylyl Cyclase by 2 ',3 '-O-(2,4,6-Trinitrophenyl)-Substituted Nucleoside 5 '-Triphosphates. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 330 (3). pp. 687-695. ISSN 0022-3565, 1521-0103

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Taha, Hesham M. and Schmidt, Jennifer and Goettle, Martin and Suryanarayana, Srividya and Shen, Yuequan and Tang, Wei-Jen and Gille, Andreas and Geduhn, Jens and Koenig, Burkhard and Dove, Stefan and Seifert, Roland (2009) Molecular Analysis of the Interaction of Anthrax Adenylyl Cyclase Toxin, Edema Factor, with 2 '(3 ')-O-(N-(methyl)anthraniloyl)-Substituted Purine and Pyrimidine Nucleotides. MOLECULAR PHARMACOLOGY, 75 (3). pp. 693-703. ISSN 0026-895X, 1521-0111

W

Weitl, Nina and Seifert, Roland (2008) Distinct Interactions of Human beta(1)- and beta(2)-Adrenoceptors with Isoproterenol, Epinephrine, Norepinephrine, and Dopamine. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 327 (3). pp. 760-769. ISSN 0022-3565

X

Xie, Sheng-Xue and Ghorai, Prasanta and Ye, Qi-Zhuang and Buschauer, Armin and Seifert, Roland (2006) Probing ligand-specific histamine H-1- and H-2-receptor conformations with N-G-acylated imidazolylpropylguanidines. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 317 (1). pp. 139-146. ISSN 0022-3565, 1521-0103

Xie, Sheng-Xue and Kraus, Anja and Ghorai, Prasanta and Ye, Qi-Zhuang and Elz, Sigurd and Buschauer, Armin and Seifert, Roland (2006) N-1-(3-cyclohexylbutanoyl)-N-2-[3-(1H-imidazol-4yl) propyl] guanidine (UR-AK57), a potent partial agonist for the human histamine H-1- and H-2-receptors. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 317 (3). pp. 1262-1268. ISSN 0022-3565, 1521-0103