Knappke, Christiane E. I. and Grupe, Sabine and Gaertner, Dominik and Corpet, Martin and Gosmini, Corinne and Jacobi von Wangelin, Axel (2014) Reductive Cross-Coupling Reactions between Two Electrophiles. CHEMISTRY-A EUROPEAN JOURNAL, 20 (23). pp. 6828-6842. ISSN 0947-6539, 1521-3765
Full text not available from this repository. (Request a copy)Abstract
Reductive cross-electrophile coupling reactions have recently been developed to a versatile and sustainable synthetic tool for selective CC bond formation. The employment of cheap and abundant electrophiles avoids the pre-formation and handling of organometallic reagents. In situ reductive coupling is effected in the presence of a transition-metal catalyst (Ni, Co, Pd, Fe) and a suitable metallic reductant (Mn, Zn, Mg). This Concept article assesses the current state of the art and summarizes recent protocols with various combinations of alkyl, alkenyl, allyl, and aryl reagents and highlights key mechanistic studies.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | UNACTIVATED ALKYL-HALIDES; COBALT-CATALYZED VINYLATION; ARYL HALIDES; ALLYLIC ACETATES; ROOM-TEMPERATURE; FUNCTIONALIZED ARYLZINC; GRIGNARD-REAGENTS; AROMATIC HALIDES; KETONE FORMATION; ORGANIC HALIDES; biaryls; cross-coupling; metalation; reduction; sustainable chemistry |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Organische Chemie > Arbeitskreis Prof. Dr. Axel Jacobi von Wangelin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 28 Oct 2019 09:27 |
| Last Modified: | 28 Oct 2019 09:27 |
| URI: | https://pred.uni-regensburg.de/id/eprint/10040 |
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