Direct formation of mesoporous upconverting core-shell nanoparticles for bioimaging of living cells

Sun, Lining and Liu, Tao and Qiu, Yannan and Liu, Jinliang and Shi, Liyi and Wolfbeis, Otto S. (2014) Direct formation of mesoporous upconverting core-shell nanoparticles for bioimaging of living cells. MICROCHIMICA ACTA, 181 (7-8). pp. 775-781. ISSN 0026-3672, 1436-5073

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Abstract

We have developed a one-step method for the synthesis of mesoporous upconverting nanoparticles (MUCNs) of the type NaYF4:Yb,Er@mSiO(2) in ammoniacal ethanol/water solution. The mesoporous silica is directly encapsulating the hydrophobic upconversion nanoparticles (UCNs) due to the presence of the template CTAB. Intense green emission (between 520 and 560 nm) and weaker red emission (between 630 and 670 nm) is observed upon 980-nm laser excitation. The MUCNs display low cytotoxicity (as revealed by an MTT test) and were successfully applied to label and image human nasopharyngeal epidermal carcinoma (KB) cells.

Item Type: Article
Uncontrolled Keywords: UP-CONVERSION NANOPARTICLES; SILICA SHELL; LUMINESCENT; UNIFORM; NANOCRYSTALS; NANOSYSTEM; Upconversion nanophosphor; Mesoporous silica; Core-shell; Luminescence imaging; Biocompatible nanoparticles
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Chemo- und Biosensorik (Prof. Antje J. Bäumner, formerly Prof. Wolfbeis)
Depositing User: Dr. Gernot Deinzer
Date Deposited: 06 Nov 2019 11:12
Last Modified: 06 Nov 2019 11:12
URI: https://pred.uni-regensburg.de/id/eprint/10133

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