Huzly, D. and Umhau, M. and Bettinger, D. and Cathomen, T. and Emmerich, F. and Hasselblatt, P. and Hengel, H. and Herzog, R. and Kappert, O. and Maassen, S. and Schorb, E. and Schulz-Huotari, C. and Thimme, R. and Unmuessig, R. and Wenzel, J. J. and Panning, M. (2014) Transfusion-transmitted hepatitis E in Germany, 2013. EUROSURVEILLANCE, 19 (21): 20812. pp. 11-14. ISSN 1560-7917,
Full text not available from this repository. (Request a copy)Abstract
The reported IgG seroprevalence against hepatitis E virus (HEV) in German blood donations is 6.8%, and HEV RNA detected in 0.08%, but documented evidence for HEV transmission is lacking. We identified two donations from a single donor containing 120 IU HEV RNA/mL plasma and 490 IU/mL. An infectious dose of 7,056 IU HEV RNA was transmitted via apheresis platelets to an immunosuppressed patient who developed chronic HEV. Further, transmission was probable in an immunocompetent child. Hepatitis E virus (HEV) infection was diagnosed in December 2013 in Germany. Retrospective analysis identified the event as the first transfusion-associated hepatitis E virus (HEV) infection in the country. Here, we report baseline virological data on the case.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | E VIRUS SEROPREVALENCE; PHYLOGENETIC ANALYSIS; UNITED-STATES; BLOOD-DONORS; ANTIBODIES; INFECTION; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin II |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 06 Nov 2019 14:20 |
| Last Modified: | 06 Nov 2019 14:20 |
| URI: | https://pred.uni-regensburg.de/id/eprint/10156 |
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