Ecker, Josef and Liebisch, Gerhard (2014) Application of stable isotopes to investigate the metabolism of fatty acids, glycerophospholipid and sphingolipid species. PROGRESS IN LIPID RESEARCH, 54. pp. 14-31. ISSN 0163-7827, 1873-2194
Full text not available from this repository. (Request a copy)Abstract
Nature provides an enormous diversity of lipid molecules that originate from various pathways. To gain insight into the metabolism and dynamics of lipid species, the application of stable isotope-labeled tracers combined with mass spectrometric analysis represents a perfect tool. This review provides an overview of strategies to track fatty acid, glycerophospholipid, and sphingolipid metabolism. In particular, the selection of stable isotope-labeled precursors and their mass spectrometric analysis is discussed. Furthermore, examples of metabolic studies that were performed in cell culture, animal and clinical experiments are presented. (C) 2014 Elsevier Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TANDEM MASS-SPECTROMETRY; CONJUGATED LINOLEIC-ACID; HIGH-THROUGHPUT QUANTIFICATION; LACTATING DAIRY-CATTLE; CDP-CHOLINE PATHWAY; IN-VIVO; QUANTITATIVE-ANALYSIS; PHOSPHATIDYLCHOLINE SYNTHESIS; MULTIPLE PRECURSOR; PHOSPHATIDYLETHANOLAMINE METHYLATION; Lipid biosynthesis; Lipid metabolism; Metabolic profiling; Stable isotope labeling; Mass spectrometry; Lipidomics |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin |
| Depositing User: | Petra Gürster |
| Date Deposited: | 24 Jul 2020 07:44 |
| Last Modified: | 24 Jul 2020 07:44 |
| URI: | https://pred.uni-regensburg.de/id/eprint/10345 |
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