von Breitenbuch, Philipp and Jeiter, Tonia and Schreml, Stephan and Glockzin, Gabriel and Agha, Ayman and Piso, Pompiliu and Schlitt, Hans J. (2014) Autofluorescent Imaging in Patients With Peritoneal Carcinomatosis. SURGICAL INNOVATION, 21 (2). pp. 187-193. ISSN 1553-3506, 1553-3514
Full text not available from this repository. (Request a copy)Abstract
Background and objectives. Autofluorescence imaging (AFI) is mainly used to detect (pre)cancerous colorectal and pulmonal lesions. This is the first report establishing the feasibility of AFI in patients with peritoneal carcinomatosis (PC). Methods. This is a prospective analysis of 10 patients undergoing conventional white-light laparoscopy (WL) and AFI for PC of different gastrointestinal tumors and 1 ovarian cancer. Before taking biopsies, suspicious peritoneal lesions were first detected by WL and then investigated by AFI. The intraoperative findings were photographed and then correlated with histological results. Results. Conventional WL and AFI evaluation was successful in all patients. A total of 38 biopsies were taken. The neoplasm detection rate under WL was 66% and increased to 86% when using AFI. The positive tumor detection rate was slightly higher in low AF lesions (83 vs 88%) and higher in tumor nodules (94%) than in flat peritoneal lesions (75%). For tumor nodules, the sensitivity was 94%, and the specificity was 100%. For flat lesions, the sensitivity was 75% and specificity 50%. Conclusions. We demonstrate the feasibility and effectiveness of AFI in patients with PC.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PERIOPERATIVE INTRAPERITONEAL CHEMOTHERAPY; PREINVASIVE BRONCHIAL LESIONS; ULCERATIVE-COLITIS; COLORECTAL-CANCER; COMPLETE CYTOREDUCTION; BARRETTS-ESOPHAGUS; EARLY NEOPLASIA; DIAGNOSIS; BRONCHOSCOPY; COLONOSCOPY; visualization; laparoscopy; tumor |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Nov 2019 15:40 |
| Last Modified: | 14 Nov 2019 15:40 |
| URI: | https://pred.uni-regensburg.de/id/eprint/10360 |
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