Interaction of anesthetics and analgesics with tumor cells

Bundscherer, A. and Malsy, M. and Bitzinger, D. and Graf, B. M. (2014) Interaction of anesthetics and analgesics with tumor cells. ANAESTHESIST, 63 (4). pp. 313-325. ISSN 0003-2417, 1432-055X

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Abstract

The results of preclinical and clinical studies indicate that the perioperative period is a vulnerable period for cancer progression and metastasis. The risk of cancer cell dissemination is enhanced by the combination of surgical manipulation and perioperative immunosuppression. Whether the oncological outcome of cancer patients can be influenced by the choice of anesthetic techniques is still a matter of debate. This review summarizes the molecular characteristics of cancer and interaction of anesthetic and analgesic drugs with cancer cells.

Item Type: Article
Uncontrolled Keywords: HEPATOCELLULAR-CARCINOMA CELLS; INDUCED GROWTH-INHIBITION; MU-OPIOID RECEPTOR; BREAST-CANCER; INDUCED APOPTOSIS; LOCAL-ANESTHETICS; DOWN-REGULATION; IN-VITRO; CELECOXIB SUPPRESSES; EPIDURAL ANALGESIA; Cancer; Apoptosis; Angiogenesis; Metastasis; Anesthetics
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Anästhesiologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 15 Nov 2019 08:41
Last Modified: 15 Nov 2019 08:41
URI: https://pred.uni-regensburg.de/id/eprint/10363

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