Baumeister, Sebastian E. and Leitzmann, Michael F. and Bahls, Martin and Doerr, Marcus and Schmid, Daniela and Schomerus, Georg and Appel, Katja and Markus, Marcello R. P. and Voelzke, Henry and Glaeser, Sven and Grabe, Hans-Joergen (2017) Associations of Leisure-Time and Occupational Physical Activity and Cardiorespiratory Fitness With Incident and Recurrent Major Depressive Disorder, Depressive Symptoms, and Incident Anxiety in a General Population. JOURNAL OF CLINICAL PSYCHIATRY, 78 (1). E41-E47. ISSN 0160-6689, 1555-2101
Full text not available from this repository. (Request a copy)Abstract
Objective: Physical activity and cardiorespiratory fitness may help prevent depression and anxiety. Previous studies have been limited by error-prone measurements. We examined whether self-reported physical activity domains and peak exercise capacity (peakVO(2)) are associated with incident and recurrent major depressive disorder (MDD), depressive symptoms, and anxiety disorders. Methods: This was a prospective population-based study of 1,080 adult men and women (25-83 years) with a median follow-up of 4.5 years and measures of physical activity during leisure time, sports, and work (Baecke questionnaire); a measure of depressive symptoms (Beck Depression Inventory II); symptom-limited cycle ergometer testing (peakVO(2), oxygen uptake at anaerobic threshold [VO2@AT], maximum power output at peak exertion); and a structured psychiatric interview (Munich Composite International Diagnostic Interview). Baseline data were collected between 2002 and 2006, and follow-up data, between 2007 and 2010. Results: After adjustment for age, sex, education, smoking, alcohol consumption, and waist circumference, the relative risks for incident MDD per standard deviation (SD) increase in leisure-time physical activity, physical activity during sport, physical activity at work, peakVO(2), VO2@AT, and maximum power output were 1.002 (95% confidence interval, 0.90 to 1.12), 1.02 (0.90 to 1.15), 0.94 (0.80 to 1.10), 0.71 (0.52 to 0.98), 0.83 (0.66 to 1.04), and 0.71 (0.52 to 0.96), respectively. PeakVO(2), VO2@AT, and maximum power output were associated with recurrent MDD, depressive symptoms, and anxiety. PeakVO(2) was more strongly related to the co-occurrence of MDD and anxiety (adjusted odds ratio [OR] = 0.45 [0.24 to 0.84]) than depression or anxiety alone (OR = 0.71 [0.53 to 0.94]). Conclusions: Greater cardiorespiratory fitness but not domain-specific physical activity was associated with a lower incidence of MDD and clinical anxiety.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | INTERNATIONAL DIAGNOSTIC INTERVIEW; ALL-CAUSE MORTALITY; CARDIOVASCULAR-DISEASE; MENTAL-HEALTH; LIFE-STYLE; CES-D; WOMEN; EXERCISE; METAANALYSIS; ADULTS; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Institut für Epidemiologie und Präventivmedizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Dec 2018 12:58 |
| Last Modified: | 22 Feb 2019 10:23 |
| URI: | https://pred.uni-regensburg.de/id/eprint/106 |
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