Ritchie, Simon A. and Beachkofsky, Thomas and Schreml, Stephan and Gaspari, Anthony and Hivnor, Chad M. (2014) Primary Localized Cutaneous Nodular Amyloidosis of the Feet: A Case Report and Review of the Literature. CUTIS, 93 (2). pp. 89-94. ISSN 0011-4162
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Primary localized cutaneous nodular amyloidosis (PLCNA) is a rare disorder that manifests as the cutaneous formation of nodules composed of light-chain amyloid. Although the type of amyloid deposit is similar to primary systemic amyloidosis, there seems to be little, if any, crossover between the 2 diseases. Because reports of PLCNA are sparse, there is no established protocol for treating this disease. This case report presents a 42-year-old man with a visually striking presentation of PLCNA on both feet with some of the lesions possibly being secondary to trauma, a rare phenomenon. The lesions had been present for more than 4 years, and there were no signs or symptoms of systemic amyloidosis. The lesions responded well to a combination of complete curettage followed by CO2 laser ablation. Primary localized cutaneous nodular amyloidosis is rare and difficult to treat, with high rates of recurrence and a concern for progression to systemic amyloidosis. The diagnosis, workup, treatment, and monitoring of PLCNA also are discussed.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TERM-FOLLOW-UP; SYSTEMIC AMYLOIDOSIS; INVOLVEMENT; SCLEROSIS; EXCISION; LASER; SKIN; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Dermatologie und Venerologie |
| Depositing User: | Petra Gürster |
| Date Deposited: | 21 Jul 2020 10:26 |
| Last Modified: | 21 Jul 2020 10:26 |
| URI: | https://pred.uni-regensburg.de/id/eprint/10728 |
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