Guillain-Barre syndrome associated with autochthonous infection by hepatitis E virus subgenotype 3c

Scharn, N. and Ganzenmueller, T. and Wenzel, J. J. and Dengler, R. and Heim, A. and Wegner, F. (2014) Guillain-Barre syndrome associated with autochthonous infection by hepatitis E virus subgenotype 3c. INFECTION, 42 (1). pp. 171-173. ISSN 0300-8126, 1439-0973

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Abstract

In this report, we present a case of a 50-year-old immunocompetent man with Guillain-Barr, syndrome (GBS) associated with an autochthonous hepatitis E virus (HEV) infection. The patient presented with tetraparesis and elevated liver enzymes. HEV infection was confirmed serologically and by polymerase chain reaction (PCR) from blood and stool. Phylogenetic analysis revealed a novel HEV genotype 3 isolate closely related to other subgenotype 3c isolates from pig livers purchased in Germany. This indicates an autochthonous, potentially food-related hepatitis E and is, to our knowledge, the first report about a neurological syndrome associated with an HEV subgenotype 3c infection.

Item Type: Article
Uncontrolled Keywords: EPIDEMIOLOGY; Guillain-Barre syndrome; Hepatitis E virus; Subgenotype 3c
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Depositing User: Dr. Gernot Deinzer
Date Deposited: 28 Nov 2019 09:22
Last Modified: 28 Nov 2019 09:22
URI: https://pred.uni-regensburg.de/id/eprint/10750

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