Osante, Inaki and Polo, Ester and Revilla-Lopez, Guillermo and de la Fuente, Jesus M. and Aleman, Carlos and Cativiela, Carlos and Diaz Diaz, David (2014) alpha-Alkyl cysteine-coated gold nanoparticles: effect of C alpha-tetrasubstitution on colloidal stability. JOURNAL OF NANOPARTICLE RESEARCH, 16 (2): 2224. ISSN 1388-0764, 1572-896X
Full text not available from this repository. (Request a copy)Abstract
In this work, we report the synthesis of new alpha-methyl L-cysteine-coated gold nanoparticles (average core diameter ca. 3 nm) and the remarkable enhancement of their aqueous stability against aggregation in comparison with the nanoparticles capped with unmodified L-cysteine under the same experimental conditions. Atomistic molecular dynamics simulations of model gold surfaces capped with L-cysteine or alpha-methyl L-cysteine revealed important differences in both the organization of the amino acids with respect to the surface and their spontaneous assembly with neighboring molecules. These differences, which are originated by the introduction of the alpha-methyl group in the amino acid, could be associated with the observed increase in stability and dispersibility of the composites in aqueous solutions at different pH values and ionic concentrations.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ; Gold nanoparticles; Cysteine; C alpha-tetrasubstitution; Colloidal stability; Molecular dynamics; Modeling and simulation |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Organische Chemie > Arbeitskreis Prof. Dr. David Díaz Díaz |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 29 Nov 2019 07:34 |
| Last Modified: | 29 Nov 2019 07:34 |
| URI: | https://pred.uni-regensburg.de/id/eprint/10821 |
Actions (login required)
 |
View Item |
