Matlock-Colangelo, Lauren and Baeumner, Antje J. (2014) Biologically Inspired Nanofibers for Use in Translational Bioanalytical Systems. In: UNSPECIFIED Annual Review of Analytical Chemistry,, 7 . ANNUAL REVIEWS, PALO ALTO, pp. 23-42. ISBN 978-0-8243-4407-8
Full text not available from this repository. (Request a copy)Abstract
Electrospun nanofiber mats are characterized by large surface-area-to-volume ratios, high porosities, and a diverse range of chemical functionalities. Although electrospun nanofibers have been used successfully to increase the immobilization efficiency of biorecognition elements and improve the sensitivity of biosensors, the full potential of nanofiber-based biosensing has not yet been realized. Therefore, this review presents novel electrospun nanofiber chemistries developed in fields such as tissue engineering and drug delivery that have direct application within the field of biosensing. Specifically, this review focuses on fibers that directly encapsulate biological additives that serve as immobilization matrices for biological species and that are used to create biomimetic scaffolds. Biosensors that incorporate these nanofibers are presented, along with potential future biosensing applications such as the development of cell culture and in vivo sensors.
| Item Type: | Book Section |
|---|---|
| Uncontrolled Keywords: | MESENCHYMAL STEM-CELLS; BOVINE SERUM-ALBUMIN; IN-VIVO MEASUREMENTS; ELECTROSPUN NANOFIBERS; DIRECT ELECTROCHEMISTRY; POLYMER NANOFIBERS; POLY(D,L-LACTIDE-CO-GLYCOLIDE) SCAFFOLDS; EXTRACELLULAR-MATRIX; CONTROLLED-RELEASE; GLOBULAR-PROTEINS; electrospinning; lab-on-a-chip; biofunctional nanofibers; biosensing |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Chemo- und Biosensorik (Prof. Antje J. Bäumner, formerly Prof. Wolfbeis) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 20 May 2020 05:09 |
| Last Modified: | 20 May 2020 05:09 |
| URI: | https://pred.uni-regensburg.de/id/eprint/10860 |
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