Vesicular aptasensor for the detection of thrombin

Mueller, Andreas and Koenig, Burkhard (2014) Vesicular aptasensor for the detection of thrombin. CHEMICAL COMMUNICATIONS, 50 (84). pp. 12665-12668. ISSN 1359-7345, 1364-548X

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Abstract

Self-assembled phospholipid vesicles are functionalized with thrombin-binding aptamers using a thiol-click reaction. The resulting aptasensors signal the binding of the analyte to the vesicle surface by changes of the emission properties of membrane co-embedded reporter dyes.

Item Type: Article
Uncontrolled Keywords: HUMAN ALPHA-THROMBIN; COLORIMETRIC DETECTION; ANCHORED DNA; LABEL-FREE; APTAMER; MOLECULES; PROTEINS; BINDING; OLIGONUCLEOTIDES; EFFICIENCIES;
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Depositing User: Dr. Gernot Deinzer
Date Deposited: 29 Nov 2019 08:03
Last Modified: 29 Nov 2019 08:03
URI: https://pred.uni-regensburg.de/id/eprint/10920

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