Schaferling, Michael and Lang, Thomas and Schnettelker, Annette (2014) A Zinc-dipicolylethylenediamine Modified Near Infrared Fluorophore for Sensing of ATP. JOURNAL OF FLUORESCENCE, 24 (1). pp. 251-256. ISSN 1053-0509, 1573-4994
Full text not available from this repository. (Request a copy)Abstract
The development of fluorescent probes for sensing of anions in biological environments is still a demanding task. Due to the structural versatility of biological active anions there are many challenges to cope with compared to fluoroionophores for the determination of metal cations. This concerns particularly the design of the recognition element, which has to provide a selective response, preferably unaffected by alterations of pH and ionic strength. Polyphosphate anions such as ATP are interesting targets in bioanalysis because they are involved in many enzymatic reactions and bear versatile biological functions. Zinc dipicolylamine complexes attached to fluorophores have been turned out to be promising candidates for ATP sensing with sufficient sensitivity and selectivity. We now report the first NIR probe that responds to ATP based on a zinc dipicolylethylenediamine receptor. It shows a "turn-on" fluorescence behavior which is selective to other polyphosphate species even at high ionic strength of the sample solution.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | NUCLEOSIDE POLYPHOSPHATES; FLUORESCENT-PROBES; RECOGNITION; PHOSPHATES; ASSAY; POLYTHIOPHENE; CHEMOSENSORS; COMPLEX; SENSORS; DESIGN; Fluorescent probe; Anions; ATP; Dipicolylethylenediamine; NIR dye |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 29 Nov 2019 11:05 |
| Last Modified: | 29 Nov 2019 11:05 |
| URI: | https://pred.uni-regensburg.de/id/eprint/11025 |
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