Klinkhammer-Schalke, Monika and Gerken, Michael and Barlag, Hagen and Hofstaedter, Ferdinand and Benz, Stefan (2017) Importance of the cancer registry in health care research. Registry studies vs. clinical studies using the example of colon cancer. ONKOLOGE, 23 (4). pp. 280-287. ISSN 0947-8965, 1433-0415
Full text not available from this repository. (Request a copy)Abstract
Routine care of cancer patients differs from the structured setting of randomized controlled clinical trials. In routine care, patients of all age groups are treated and often suffer from multiple comorbidities. Therefore, results from clinical trials cannot always be directly applied to the routine care setting. The aim of this review is to gather the clinical cancer registry data regarding questions of quality of care and health services research. Outcome data of clinical cancer registries were collected nationwide and presented in 2016 at the 6(th) national oncology quality conference in Berlin. The implementation and survival benefit of colon cancer patients were reviewed based on surgical procedures, especially laparoscopy vs. laparotomy. Similarly, the outcome of adjuvant chemotherapy in patients with stage II colon cancer was presented using data from population-based cancer registries. The nationwide analysis showed a significantly better survival for patients with minimally invasive operations in stages I-III which is in line with data from other registries but in contrast to randomized trials. In another analysis patients with T4 stage II colon cancer benefited significantly from adjuvant chemotherapy. The best survival was reached by application of adjuvant chemotherapy for colon carcinoma stage III within 19-44 days. Registry data can be used for the measurement of treatment quality and for health services research. In the future more registry-based studies should be conducted to demonstrate the real world outcomes.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CHEMOTHERAPY; MORTALITY; BENEFIT; Data collection; Colonic neoplasms; Quality assurance, health care; Health care evaluation mechanisms; Health services research |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Zentren des Universitätsklinikums Regensburg > Tumorzentrum e.V. |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Dec 2018 13:11 |
| Last Modified: | 18 Feb 2019 14:06 |
| URI: | https://pred.uni-regensburg.de/id/eprint/1144 |
Actions (login required)
 |
View Item |
