Pummer, Andreas and Knuettel, Helge and Hiller, Karl-Anton and Buchalla, Wolfgang and Cieplik, Fabian and Maisch, Tim (2017) Antimicrobial efficacy of irradiation with visible light on oral bacteria in vitro: a systematic review. FUTURE MEDICINAL CHEMISTRY, 9 (13). pp. 1557-1574. ISSN 1756-8919, 1756-8927
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Aim: Resistances to antibiotics employed for treatment of infectious diseases have increased to alarming numbers making it more and more difficult to treat diseases caused by microorganisms resistant to common antibiotics. Consequently, novel methods for successful inactivation of pathogens are required. In this instance, one alternative could be application of light for treatment of topical infections. Antimicrobial properties of UV light are well documented, but due to its DNA-damaging properties use for medical purposes is limited. In contrast, irradiation with visible light may be more promising. Methods: Literature was systematically screened for research concerning inactivation of main oral bacterial species by means of visible light. Results: Inactivation of bacterial species, especially pigmented ones, in planktonic state showed promising results. There is a lack of research examining the situation when organized as biofilms. Conclusion: More research concerning situation in a biofilm state is required.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PORPHYROMONAS-GINGIVALIS; BLUE-LIGHT; STAPHYLOCOCCUS-AUREUS; STREPTOCOCCUS-MUTANS; LETHAL PHOTOSENSITIZATION; FUSOBACTERIUM-NUCLEATUM; ENDOGENOUS PORPHYRINS; ANAEROBIC CONDITIONS; HELICOBACTER-PYLORI; ARGON-LASER; antimicrobial; bacteria; light; oral; visible |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Dermatologie und Venerologie Medicine > Lehrstuhl für Zahnerhaltung und Parodontologie > Dr. rer. nat. Karl-Anton Hiller Central Institutions > University Library |
| Depositing User: | Petra Gürster |
| Date Deposited: | 14 Dec 2018 13:15 |
| Last Modified: | 11 Sep 2020 05:42 |
| URI: | https://pred.uni-regensburg.de/id/eprint/1236 |
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