Heratizadeh, Annice and Werfel, Thomas and Wollenberg, Andreas and Abraham, Susanne and Plank-Habibi, Sibylle and Schnopp, Christina and Sticherling, Michael and Apfelbacher, Christian and Biedermann, Tilo and Breuer, Kristine and Fell, Isabel and Foelster-Holst, Regina and Heine, Guido and Grimm, Jennifer and Hennighausen, Lars and Kugler, Claudia and Reese, Imke and Ring, Johannes and Schakel, Knut and Schmitt, Jochen and Seikowski, Kurt and von Stebut, Esther and Wagner, Nicola and Wassmann-Otto, Anja and Wienke-Graul, Ute and Weisshaar, Elke and Worm, Margitta and Gieler, Uwe and Kupfer, Joerg (2017) Effects of structured patient education in adults with atopic dermatitis: Multicenter randomized controlled trial. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 140 (3). 845-+. ISSN 0091-6749, 1097-6825
Full text not available from this repository. (Request a copy)Abstract
Background: Atopic dermatitis (AD) is a chronic relapsing skin disease prevalent in 1% to 3% of adults in Western industrialized countries. Objective: We sought to investigate the effectiveness of educational training in an outpatient setting on coping with the disease, quality of life, symptoms, and severity in adults with AD. Methods: In this German prospective, randomized controlled multicenter study, adult patients with moderate-to-severe AD were educated by referring to a comprehensive 12-hour training manual consented by a multiprofessional study group from different centers (Arbeitsgemeinschaft Neurodermitisschulung fur Erwachsene [ARNE]). Patients were randomly allocated to the intervention or waiting control groups. Study visits were performed at baseline and after 1 year (1 year of follow-up). Primary outcomes were defined as a decrease in (1) "catastrophizing cognitions'' with respect to itching (Juckreiz-Kognitions-Fragebogen questionnaire), (2) "social anxiety'' (Marburger Hautfragebogen questionnaire), (3) subjective burden by symptoms of the disease (Skindex-29 questionnaire), and (4) improvement of disease signs and symptoms assessed by using the SCORAD index at 1 year of follow-up. Data were analyzed on an intention-to-treat basis. Results: At 1 year of follow-up, patients from the intervention group (n = 168) showed a significantly better improvement compared with the waiting group (n = 147) in the following defined primary study outcomes: coping behavior with respect to itching (P < .001), quality of life assessed by using the Skindex-29 questionnaire (P < .001), and the SCORAD index (P < .001). Conclusions: This is the first randomized, controlled multicenter study on patient education in adult AD. The ARNE training program shows significant beneficial effects on a variety of psychosocial parameters, as well as AD severity.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | QUALITY-OF-LIFE; NATIONAL-HEALTH CARE; PATIENTS PERSPECTIVE; PEDIATRIC-PATIENTS; CLINICAL SIGNS; POSITION PAPER; DISEASE BURDEN; ECZEMA; DERMATOLOGY; VALIDATION; Atopic dermatitis; adulthood; patient education; multi-professional; psychosocial; disease severity; quality of life; coping |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Institut für Epidemiologie und Präventivmedizin > Medical Sociology |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Dec 2018 13:15 |
| Last Modified: | 19 Feb 2019 13:08 |
| URI: | https://pred.uni-regensburg.de/id/eprint/1306 |
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