Combes, Alain and Brodie, Dan and Chen, Yih-Sharng and Fan, Eddy and Henriques, Jose P. S. and Hodgson, Carol and Lepper, Philipp M. and Leprince, Pascal and Maekawa, Kunihiko and Mueller, Thomas and Nuding, Sebastian and Ouweneel, Dagmar M. and Roch, Antoine and Schmidt, Matthieu and Takayama, Hiroo and Vuylsteke, Alain and Werdan, Karl and Papazian, Laurent (2017) The ICM research agenda on extracorporeal life support. INTENSIVE CARE MEDICINE, 43 (9). pp. 1306-1318. ISSN 0342-4642, 1432-1238
Full text not available from this repository. (Request a copy)Abstract
Purpose: This study aimed to concisely describe the current standards of care, major recent advances, common beliefs that have been contradicted by recent trials, areas of uncertainty, and clinical studies that need to be performed over the next decade and their expected outcomes with regard to extracorporeal membrane oxygenation (ECMO). Methods: Narrative review based on a systematic analysis of the medical literature, national and international guidelines, and expert opinion. Results: The use of venovenous ECMO (VV-ECMO) is increasing in the most severe forms of acute lung injury. In patients with cardiogenic shock, short-term veno-arterial ECMO (VA-ECMO) provides both pulmonary and circulatory support. Technological improvements and recently published studies suggest that ECMO is able to improve patients' outcomes. There are, however, many uncertainties regarding the real benefits of this technique both in hemodynamic and respiratory failure, the territorial organization to deliver ECMO, the indications and the use of concomitant treatments. Conclusions: Although there have been considerable advances regarding the use of ECMO in critically ill patients, the risk/benefit ratio remains underinvestigated. ECMO indications, organization of ECMO delivery, and use of adjuvant therapeutics need also to be explored. Ongoing and future studies may be able to resolve these issues.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | RESPIRATORY-DISTRESS-SYNDROME; REFRACTORY CARDIOGENIC-SHOCK; MECHANICAL CIRCULATORY SUPPORT; HOSPITAL CARDIAC-ARREST; CONVENTIONAL CARDIOPULMONARY-RESUSCITATION; ACUTE MYOCARDIAL-INFARCTION; INTRAAORTIC BALLOON PUMP; 2009 INFLUENZA A(H1N1); MEMBRANE-OXYGENATION SUPPORT; MORTALITY RISK SCORE; Extracorporeal membrane oxygenation; Acute respiratory distress syndrome; Cardiogenic shock; Research agenda; Position article |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin II |
| Depositing User: | Petra Gürster |
| Date Deposited: | 14 Dec 2018 13:15 |
| Last Modified: | 17 Sep 2020 07:29 |
| URI: | https://pred.uni-regensburg.de/id/eprint/1324 |
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