Noguchi, Shuhei and Arakawa, Takahiro and Fukuda, Shiro and Furuno, Masaaki and Hasegawa, Akira and Hori, Fumi and Ishikawa-Kato, Sachi and Kaida, Kaoru and Kaiho, Ai and Kanamori-Katayama, Mutsumi and Kawashima, Tsugumi and Kojima, Miki and Kubosaki, Atsutaka and Manabe, Ri-ichiroh and Murata, Mitsuyoshi and Nagao-Sato, Sayaka and Nakazato, Kenichi and Ninomiya, Noriko and Nishiyori-Sueki, Hiromi and Noma, Shohei and Saijyo, Eri and Saka, Akiko and Sakai, Mizuho and Simon, Christophe and Suzuki, Naoko and Tagami, Michihira and Watanabe, Shoko and Yoshida, Shigehiro and Arner, Peter and Axton, Richard A. and Babina, Magda and Baillie, J. Kenneth and Barnett, Timothy C. and Beckhouse, Anthony G. and Blumenthal, Antje and Bodega, Beatrice and Bonetti, Alessandro and Briggs, James and Brombacher, Frank and Carlisle, Ailsa J. and Clevers, Hans C. and Davis, Carrie A. and Detmar, Michael and Dohi, Taeko and Edge, Albert S. B. and Edinger, Matthias and Ehrlund, Anna and Ekwall, Karl and Endoh, Mitsuhiro and Enomoto, Hideki and Eslami, Afsaneh and Fagiolini, Michela and Fairbairn, Lynsey and Farach-Carson, Mary C. and Faulkner, Geoffrey J. and Ferrai, Carmelo and Fisher, Malcolm E. and Forrester, Lesley M. and Fujita, Rie and Furusawa, Jun-ichi and Geijtenbeek, Teunis B. and Gingeras, Thomas and Goldowitz, Daniel and Guhl, Sven and Guler, Reto and Gustincich, Stefano and Ha, Thomas J. and Hamaguchi, Masahide and Hara, Mitsuko and Hasegawa, Yuki and Herlyn, Meenhard and Heutink, Peter and Hitchens, Kelly J. and Hume, David A. and Ikawa, Tomokatsu and Ishizu, Yuri and Kai, Chieko and Kawamoto, Hiroshi and Kawamura, Yuki I. and Kempfle, Judith S. and Kenna, Tony J. and Kere, Juha and Khachigian, Levon M. and Kitamura, Toshio and Klein, Sarah and Klinken, S. Peter and Knox, Alan J. and Kojima, Soichi and Koseki, Haruhiko and Koyasu, Shigeo and Lee, Weonju and Lennartsson, Andreas and Mackay-sim, Alan and Mejhert, Niklas and Mizuno, Yosuke and Morikawa, Hiromasa and Morimoto, Mitsuru and Moro, Kazuyo and Morris, Kelly J. and Motohashi, Hozumi and Mummery, Christine L. and Nakachi, Yutaka and Nakahara, Fumio and Nakamura, Toshiyuki and Nakamura, Yukio and Nozaki, Tadasuke and Ogishima, Soichi and Ohkura, Naganari and Ohno, Hiroshi and Ohshima, Mitsuhiro and Okada-Hatakeyama, Mariko and Okazaki, Yasushi and Orlando, Valerio and Ovchinnikov, Dmitry A. and Passier, Robert and Patrikakis, Margaret and Pombo, Ana and Pradhan-Bhatt, Swati and Qin, Xian-Yang and Rehli, Michael and Rizzu, Patrizia and Roy, Sugata and Sajantila, Antti and Sakaguchi, Shimon and Sato, Hiroki and Satoh, Hironori and Savvi, Suzana and Saxena, Alka and Schmidl, Christian and Schneider, Claudio and Schulze-Tanzil, Gundula G. and Schwegmann, Anita and Sheng, Guojun and Shin, Jay W. and Sugiyama, Daisuke and Sugiyama, Takaaki and Summers, Kim M. and Takahashi, Naoko and Takai, Jun and Tanaka, Hiroshi and Tatsukawa, Hideki and Tomoiu, Andru and Toyoda, Hiroo and van de Wetering, Marc and van den Berg, Linda M. and Verardo, Roberto and Vijayan, Dipti and Wells, Christine A. and Winteringham, Louise N. and Wolvetang, Ernst and Yamaguchi, Yoko and Yamamoto, Masayuki and Yanagi-Mizuochi, Chiyo and Yoneda, Misako and Yonekura, Yohei and Zhang, Peter G. and Zucchelli, Silvia and Abugessaisa, Imad and Arner, Erik and Harshbarger, Jayson and Kondo, Atsushi and Lassmann, Timo and Lizio, Marina and Sahin, Serkan and Sengstag, Thierry and Severin, Jessica and Shimoji, Hisashi and Suzuki, Masanori and Suzuki, Harukazu and Kawai, Jun and Kondo, Naoto and Itoh, Masayoshi and Daub, Carsten O. and Kasukawa, Takeya and Kawaji, Hideya and Carninci, Piero and Forrest, Alistair R. R. and Hayashizaki, Yoshihide (2017) Data Descriptor: FANTOM5 CAGE profiles of human and mouse samples. SCIENTIFIC DATA, 4: 170112. ISSN 2052-4463
Full text not available from this repository. (Request a copy)Abstract
In the FANTOM5 project, transcription initiation events across the human and mouse genomes were mapped at a single base-pair resolution and their frequencies were monitored by CAGE (Cap Analysis of Gene Expression) coupled with single-molecule sequencing. Approximately three thousands of samples, consisting of a variety of primary cells, tissues, cell lines, and time series samples during cell activation and development, were subjected to a uniform pipeline of CAGE data production. The analysis pipeline started by measuring RNA extracts to assess their quality, and continued to CAGE library production by using a robotic or a manual workflow, single molecule sequencing, and computational processing to generate frequencies of transcription initiation. Resulting data represents the consequence of transcriptional regulation in each analyzed state of mammalian cells. Non-overlapping peaks over the CAGE profiles, approximately 200,000 and 150,000 peaks for the human and mouse genomes, were identified and annotated to provide precise location of known promoters as well as novel ones, and to quantify their activities.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MAMMALIAN EXPRESSION ATLAS; UCSC GENOME BROWSER; GENE-EXPRESSION; CELL-TYPES; IN-VITRO; TRANSCRIPTION; VISUALIZATION; ENHANCERS; UPDATE; GROWTH; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie) Medicine > Zentren des Universitätsklinikums Regensburg > Regensburger Centrum für Interventionelle Immunologie (RCI) |
| Depositing User: | Petra Gürster |
| Date Deposited: | 14 Dec 2018 13:15 |
| Last Modified: | 17 Sep 2020 05:24 |
| URI: | https://pred.uni-regensburg.de/id/eprint/1358 |
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