Schemmerer, M. and Rauh, C. and Jilg, W. and Wenzel, J. J. (2017) Time course of hepatitis E-specific antibodies in adults. JOURNAL OF VIRAL HEPATITIS, 24 (1). pp. 75-79. ISSN 1352-0504, 1365-2893
Full text not available from this repository. (Request a copy)Abstract
Hepatitis E virus (HEV) is highly endemic in industrialized countries, but there is a lack of knowledge on individual and overall antibody concentration dynamics. The aim of this study was to characterize longitudinal concentration changes of anti-HEV immunoglobulin G (anti-HEV IgG) by enzyme immunoassay (EIA). In total, 199 serum samples collected from 45 subjects over 18years were analysed. A wide range of anti-HEV IgG levels was found. Overall, anti-HEV IgG significantly decreased after an observation period of at least 5years. One negative seroconversion was observed. Four individual profiles suggested single and even multiple HEV reinfections despite pre-existing HEV antibodies.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | E VIRUS TRANSMISSION; INFECTION; GERMANY; FRANCE; antibody dynamics; anti-HEV IgG; hepatitis E virus; negative seroconversion; reinfection |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Dec 2018 12:58 |
| Last Modified: | 12 Feb 2019 09:53 |
| URI: | https://pred.uni-regensburg.de/id/eprint/144 |
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