Eder, Maria and Schulte-Mattler, Wilhelm and Poeschl, Peter (2017) NEUROGRAPHIC COURSE OF WALLERIAN DEGENERATION AFTER HUMAN PERIPHERAL NERVE INJURY. MUSCLE & NERVE, 56 (2). pp. 247-252. ISSN 0148-639X, 1097-4598
Full text not available from this repository. (Request a copy)Abstract
Introduction: Neurographic data on Wallerian degeneration (WD) after motor nerve injury are available only from animal studies and human case reports of 9 patients altogether. A precise knowledge of neurographic features of WD would be highly relevant for diagnostic, prognostic, therapeutic, and forensic aspects of traumatic lesions. Methods: We prospectively studied WD in patients with a peripheral nerve injury. They underwent sequential neurographic examinations beginning no later than 3 days after the injury until a plateau of the amplitude of compound muscle action potential was reached. Results: We examined 20 injured nerves from 16 patients. Four days after injury, all nerves showed amplitude decay to some extent, whereas 85% had reached their plateau at day 8. A length dependency of WD could be demonstrated. Conclusion: In humans, WD starts no later than day 4, shows length dependency, and is completed at day 8 in most nerves.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CONDUCTION; SECTION; FIBERS; MUSCLE; axonal lesion; neurography; peripheral nerve; trauma; Wallerian degeneration |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Neurologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Dec 2018 13:16 |
| Last Modified: | 12 Feb 2019 14:39 |
| URI: | https://pred.uni-regensburg.de/id/eprint/1458 |
Actions (login required)
 |
View Item |
