Malfertheiner, Sara Fill and Seelbach-Goebel, Birgit and Costa, Serban-Dan and Ernst, Wolfgang and Reuschel, Edith and Zeman, Florian and Malfertheiner, Peter and Malfertheiner, Maximilian V. (2017) Impact of gastroesophageal reflux disease symptoms on the quality of life in pregnant women: a prospective study. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 29 (8). pp. 892-896. ISSN 0954-691X, 1473-5687
Full text not available from this repository. (Request a copy)Abstract
Objective Pregnant women often suffer from gastroesophageal reflux disease (GERD). GERD symptoms are known to influence the quality of life; however, there is a lack of data in pregnant women. The aim of this study was to establish the impact of GERD symptoms on health-related quality of life (HRQOL) during pregnancy. Participants and methods A prospective longitudinal cohort study to investigate the impact of GERD symptoms on the HRQOL was carried out in 510 pregnant women and 330 nonpregnant women as controls. Two validated questionnaires, the Reflux Disease Questionnaire and the Quality of Life in Reflux and Dyspepsia Questionnaire, were used. Results The study showed a significant negative impact on HRQOL in pregnant women with GERD symptoms. All five areas, emotional distress, sleep disturbance, vitality, food/drink problems, and physical/social functioning, were significantly reduced, but the most significant impact was on sleep (Quality of Life in Reflux and Dyspepsia Questionnaire score - 35%). Overall, quality of life in women with GERD worsened throughout pregnancy. Conclusion GERD is frequently seen in pregnant women and has a negative impact on HRQOL, especially in late pregnancy. Therefore, there is a need for adequate therapy of GERD in pregnant women and HRQOL could be an adequate monitoring tool in this population. Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MONTREAL DEFINITION; HEALTH; QUESTIONNAIRE; COHORT; GERD; gastroesophageal reflux disease; heartburn; health-related quality of life; pregnancy; quality of life |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Frauenheilkunde und Geburtshilfe (Schwerpunkt Geburtshilfe) Medicine > Lehrstuhl für Innere Medizin II Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Klinische Studien |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Dec 2018 13:16 |
| Last Modified: | 28 Feb 2019 12:04 |
| URI: | https://pred.uni-regensburg.de/id/eprint/1500 |
Actions (login required)
 |
View Item |
