Bruendl, Elisabeth and Schoedel, Petra and Bele, Sylvia and Proescholdt, Martin and Scheitzach, Judith and Zeman, Florian and Brawanski, Alexander and Schebesch, Karl-Michael (2018) Treatment of Spontaneous Subarachnoid Hemorrhage and Self-Reported Neuropsychological Performance at 6 Months - Results of a Prospective Clinical Pilot Study on Good-Grade Patients. TURKISH NEUROSURGERY, 28 (3). pp. 369-388. ISSN 1019-5149,
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AIM: Limited focus has been placed on neuropsychological patient profiles after spontaneous subarachnoid hemorrhage (sSAH). We conducted a prospective controlled study in good-grade sSAH patients to evaluate the time course of treatment-specific differences in cognitive processing after sSAH. MATERIAL and METHODS: Twenty-six consecutive sSAH patients were enrolled (drop out n=5). Nine patients received endovascular aneurysm occlusion (EV), 6 patients were treated microsurgically (MS), and 6 patients with perimesencephalic SAH (pSAH) underwent standardized intensive medical care. No patient experienced serious vasospasm-related ischemic or hemorrhagic complications. All patients were subjected to neuropsychological self-report assessment (36-Item Short Form Health Survey and ICD-10-Symptom-Rating questionnaire) subacutely (day 11 - 35) after the onset of bleeding (t 1) and at the 6-month follow-up (FU; t 2). RESULTS: From t 1 to t 2, MS and EV patients significantly improved in physical functioning (Pfi; p=.001 each) and the physical component summary (p=.010 vs. p=.015). Bodily pain (Pain; MS p=.034) and general health perceptions (EV p=.014) significantly improved, and nutrition disorder (EV p=.008) worsened. At FU, MS patients reported significantly better Pfi (vs. EV p=.046), less Pain (vs. EV p=.040), and more depression (vs. pSAH p=.035). Group-rate analyses of test differences showed a significant alleviation in nutrition disorder in MS (vs. EV p=.009). CONCLUSION: All sSAH groups reported a significant deterioration in health. Though both MS and EV patients, improved in several physical items over time, our data suggest a better short-term Pfi, less Pain and improved nutrition disorder in surgically treated patients. pSAH patients performed significantly better in various aspects of physical and psychological functioning than patients with aneurysmal SAH.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | QUALITY-OF-LIFE; POSTTRAUMATIC-STRESS-DISORDER; COMMUNICATING ARTERY ANEURYSM; RUPTURED INTRACRANIAL ANEURYSMS; GOOD NEUROLOGICAL RECOVERY; LONG-TERM; ENDOVASCULAR COILING; COGNITIVE IMPAIRMENT; CEREBRAL ANEURYSMS; FOLLOW-UP; Clip; Cognitive impairment; Coil; Neuropsychological outcome; Subarachnoid hemorrhage |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Neurochirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 20 Mar 2020 08:00 |
| Last Modified: | 20 Mar 2020 08:00 |
| URI: | https://pred.uni-regensburg.de/id/eprint/15292 |
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