Jockenhoefer, Finja and Gollnick, Harald and Herberger, Katharina and Isbary, Georg and Renner, Regina and Stuecker, Markus and Valesky, Eva and Wollina, Uwe and Weichenthal, Michael and Karrer, Sigrid and Klode, Joachim and Dissemond, Joachim (2013) Bacteriological pathogen spectrum of chronic leg ulcers: Results of a multicenter trial in dermatologic wound care centers differentiated by regions. JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 11 (11). pp. 1057-1064. ISSN 1610-0379, 1610-0387
Full text not available from this repository. (Request a copy)Abstract
Background: In almost every chronic wound different bacteria species can be detected. Patients and methods: Retrospective, multicenter evaluation of bacterial swab results from 2010 and 2011 in patients with chronic leg ulcer treated in 10 dermatologic wound care centers from 5 regions in Germany. Results: Data of 970 patients were analyzed. Staphylococcus aureus was detected in 47.6 % of the patients, 8.6 % of these were methicillin-resistant (MRSA). Pseudomonas aeruginosa was found in 31.1 %, enterobacteria in 28.6 % and Proteus mirabilis in 13.7 % of the patients. The regional comparison showed a significant south-north gradient for S. aureus, P. aeruginosa, and enterobacteria. Moreover, a highly significant west-east gradient for MRSA was found with detection rates of 13.5 % in the west to 4.0 % in the east. Furthermore, nationally there was a significant negative correlation between S. aureus and P. aeruginosa or P. mirabilis, respectively, as well as a positive correlation of P. aeruginosa with respect to wound size and duration. In addition to climatic and therapeutic conditions, different regional health care structures are discussed as potentially relevant reasons for these significantly different regional detection rates. Conclusions: Our data show the regional variability of the spectrum of currently detected bacteria in patients with chronic leg ulcers in Germany.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | RESISTANT STAPHYLOCOCCUS-AUREUS; PSEUDOMONAS-AERUGINOSA; BACTERIAL-COLONIZATION; MICROBIOLOGY; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Dermatologie und Venerologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 31 Mar 2020 07:02 |
| Last Modified: | 31 Mar 2020 07:02 |
| URI: | https://pred.uni-regensburg.de/id/eprint/15796 |
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