Vaginal Estrogen Therapy for Patients with Breast Cancer

Moegele, M. and Buchholz, S. and Seitz, S. and Lattrich, C. and Ortmann, O. (2013) Vaginal Estrogen Therapy for Patients with Breast Cancer. GEBURTSHILFE UND FRAUENHEILKUNDE, 73 (10). pp. 1017-1022. ISSN 0016-5751, 1438-8804

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Abstract

On account of the good prognosis for patients with breast cancer, improving or maintaining the quality of life in the aftercare period is becoming more and more important. In particular, the increasing usage of aromatase inhibitors in the past few years has led to an increased incidence of vaginal atrophy with symptoms such as vaginal dryness, petechial bleeding, dyspareunia and recurrent cystitis. And just these symptoms have a detrimental impact on the quality of life of breast cancer patients. Application of a topical estrogen therapy represents the most effective means to treat vaginal atrophy. The use of a systemic or, respectively, topical hormone therapy is, however, contraindicated for breast cancer patients. Further clinical trials are needed in order to assess the safety of vaginal estrogen therapy.

Item Type: Article
Uncontrolled Keywords: POSTMENOPAUSAL HORMONE-THERAPY; RANDOMIZED CONTROLLED-TRIAL; 0.03 MG ESTRIOL; REPLACEMENT THERAPY; MENOPAUSAL SYMPTOMS; ENDOCRINE THERAPY; PLUS PROGESTIN; DOUBLE-BLIND; WOMEN; ATROPHY; breast cancer; vaginal atrophy; hormone therapy; quality of life
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Frauenheilkunde und Geburtshilfe (Schwerpunkt Frauenheilkunde)
Depositing User: Dr. Gernot Deinzer
Date Deposited: 30 Mar 2020 05:44
Last Modified: 30 Mar 2020 05:44
URI: https://pred.uni-regensburg.de/id/eprint/15883

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