Langguth, Berthold and Kreuzer, Peter M. and Kleinjung, Tobias and De Ridder, Dirk (2013) Tinnitus: causes and clinical management. LANCET NEUROLOGY, 12 (9). pp. 920-930. ISSN 1474-4422, 1474-4465
Full text not available from this repository. (Request a copy)Abstract
Tinnitus is the perception of sound in the absence of a corresponding external acoustic stimulus. With prevalence ranging from 10% to 15%, tinnitus is a common disorder. Many people habituate to the phantom sound, but tinnitus severely impairs quality of life of about 1-2% of all people. Tinnitus has traditionally been regarded as an otological disorder, but advances in neuroimaging methods and development of animal models have increasingly shifted the perspective towards its neuronal correlates. Increased neuronal firing rate, enhanced neuronal synchrony, and changes in the tonotopic organisation are recorded in central auditory pathways in reaction to deprived auditory input and represent-together with changes in non-auditory brain areas-the neuronal correlate of tinnitus. Assessment of patients includes a detailed case history, measurement of hearing function, quantification of tinnitus severity, and identification of causal factors, associated symptoms, and comorbidities. Most widely used treatments for tinnitus involve counselling, and best evidence is available for cognitive behavioural therapy. New pathophysiological insights have prompted the development of innovative brain-based treatment approaches to directly target the neuronal correlates of tinnitus.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TRANSCRANIAL MAGNETIC STIMULATION; ENRICHED ACOUSTIC ENVIRONMENT; AUDITORY-CORTEX; ANIMAL-MODEL; NOISE TRAUMA; HEARING-LOSS; HOMEOSTATIC PLASTICITY; BEHAVIORAL PARADIGM; RETRAINING THERAPY; SOUND; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Psychiatrie und Psychotherapie |
| Depositing User: | Petra Gürster |
| Date Deposited: | 18 Jun 2020 10:29 |
| Last Modified: | 18 Jun 2020 10:29 |
| URI: | https://pred.uni-regensburg.de/id/eprint/16138 |
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