Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Fourth Meeting: Lessons Learned from First Clinical Trials

Franquesa, Marcella and Hoogduijn, Martin J. and Reinders, Marlies E. and Eggenhofer, Elke and Engela, Anja U. and Mensah, Fane K. and Torras, Joan and Pileggi, Antonello and van Kooten, Cees and Mahon, Bernard and Detry, Oliver and Popp, Felix C. and Benseler, Volker and Casiraghi, Federica and Johnson, Christian and Ancans, Janis and Fillenberg, Barbara and delaRosa, Olga and Aran, Josep M. and Roemeling-vanRhijn, Marieke and Pinxteren, Jef and Perico, Norberto and Gotti, Eliana and Christ, Bruno and Reading, James and Introna, Martino and Deans, Robert and Shagidulin, Murat and Farre, Ramon and Rambaldi, Alessandro and Sanchez-Fueyo, Albert and Obermajer, Natasha and Pulin, Andrey and Dor, Frank J. M. F. and Portero-Sanchez, Isabel and Baan, Carla C. and Rabelink, Ton J. and Remuzzi, Giuseppe and Betjes, Michiel G. H. and Dahlke, Marc H. and Grinyo, Josep M. (2013) Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Fourth Meeting: Lessons Learned from First Clinical Trials. TRANSPLANTATION, 96 (3). pp. 234-238. ISSN 0041-1337, 1534-6080

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Abstract

The Fourth Expert Meeting of the Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Consortium took place in Barcelona on October 19 and 20, 2012. This meeting focused on the translation of preclinical data into early clinical settings. This position paper highlights the main topics explored on the safety and efficacy of mesenchymal stem cells as a therapeutic agent in solid organ transplantation and emphasizes the issues (proper timing, concomitant immunossupression, source and immunogenicity of mesenchymal stem cells, and oncogenicity) that have been addressed and will be followed up by the MiSOT Consortium in future studies.

Item Type: Article
Uncontrolled Keywords: STROMAL CELLS; RENAL-TRANSPLANTATION; PHASE-I; THERAPY; FEASIBILITY; TACROLIMUS; REJECTION; DISEASE; SAFETY; Mesenchymal stem cells; Transplantation; Immunomodulation; Position paper
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Chirurgie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 02 Apr 2020 10:40
Last Modified: 02 Apr 2020 10:40
URI: https://pred.uni-regensburg.de/id/eprint/16227

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