Pfaff, Janina and Meister, Gunter (2013) Argonaute and GW182 proteins: an effective alliance in gene silencing. BIOCHEMICAL SOCIETY TRANSACTIONS, 41. pp. 855-860. ISSN 0300-5127,
Full text not available from this repository. (Request a copy)Abstract
Argonaute proteins interact with small RNAs and facilitate small RNA-guided gene-silencing processes. Small RNAs guide Argonaute proteins to distinct target sites on mRNAs where Argonaute proteins interact with members of the GW182 protein family (also known as GW proteins). In subsequent steps, GW182 proteins mediate the downstream steps of gene silencing. The present mini-review summarizes and discusses our current knowledge of the molecular basis of Argonaute-GW182 protein interactions.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MESSENGER-RNA DEGRADATION; CRYSTAL-STRUCTURE; STRUCTURAL BASIS; GUIDE RNA; TRANSLATIONAL REPRESSION; PIWI-DOMAIN; PAZ DOMAIN; HUMAN AGO2; GW BODIES; P-BODIES; Argonaute protein; gene silencing; GW182 protein; microRNA (miRNA); RNA interference (RNAi) |
| Subjects: | 500 Science > 570 Life sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie I > Prof. Dr. Gunter Meister |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 03 Apr 2020 13:51 |
| Last Modified: | 03 Apr 2020 13:51 |
| URI: | https://pred.uni-regensburg.de/id/eprint/16297 |
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