Beitinger, Nelly and Ehrenstein, Boris and Schreiner, Benno and Fleck, Martin and Grifka, Joachim and Luering, Christian and Hartung, Wolfgang (2013) The value of colour Doppler sonography of the knee joint: a useful tool to discriminate inflammatory from non-inflammatory disease? RHEUMATOLOGY, 52 (8). pp. 1425-1428. ISSN 1462-0324,
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Methods. Standardized CDUS examinations were performed in 111 knee joints of 106 patients (70 women and 36 men) presenting with severe OA (n = 72) or confirmed IA (n = 39) of one or both knee joints to determine the degree of synovial inflammation in a semiquantitative fashion. To definitely distinguish inflammatory from non-inflammatory disease, SF was obtained from every patient within 24 h after sonography and analysed SFs containing 1000 white blood cells (WBC)/mu l were considered non-inflammatory, whereas epsilon 5000 WBC/mu l were classified as inflammatory. Results. The CDUS sum score of OA patients was determined to be 3.3 (range 0-8). In contrast, IA patients exhibited significantly elevated synovitis score of 5.3 (range 3-9) (P < 0.001). However, high synovial CDUS activity could be observed in OA patients sporadically. Therefore, there is no definitive CDUS threshold that clearly separates OA from IA patients. Conclusion. CDUS is a valuable instrument to assist clinicians in distinguishing OA from IA of the knee joint, but nevertheless should always be interpreted within the clinical context.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | RHEUMATOID-ARTHRITIS; SYNOVIAL TISSUE; OSTEOARTHRITIS; ULTRASONOGRAPHY; power Doppler ultrasound; knee; osteoarthritis; arthritis; synovial fluid analysis |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Orthopädie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 06 Apr 2020 11:34 |
| Last Modified: | 06 Apr 2020 11:34 |
| URI: | https://pred.uni-regensburg.de/id/eprint/16340 |
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