Sayedahmed, K. and Rosenhammer, B. and Spachmann, P. J. and Burger, M. and Aragona, M. and Kaftan, B. T. and Olianas, R. and Fritsche, H. M. (2017) Bicentric prospective evaluation of corporoplasty with porcine small intestinal submucosa (SIS) in patients with severe Peyronie's disease. WORLD JOURNAL OF UROLOGY, 35 (7). pp. 1119-1124. ISSN 0724-4983, 1433-8726
Full text not available from this repository. (Request a copy)Abstract
Introduction Advanced Peyronie's disease (PD) with severe penile deviation demands grafting procedures following plaque incision or partial plaque excision in order to avoid penile shortening and to improve quality of life of affected patients. Small intestinal submucosa (SIS) is an established xenograft. The objective of the present study was to validate external results in a bicentric prospective manner. Methods Patient selection criteria, surgical technique and standards for pre- and postoperative care were defined. Consecutively, patients with severe penile deviation in stable disease and sufficient erectile function were included between 2007 and 2015. After plaque incision, grafting was performed using SIS in a standardized manner. The postoperative evaluation using a non-validated questionnaire included complications, correction of curvature, pre- and postoperative erectile function, change in penile length and general satisfaction with the procedure. Results Forty-three patients underwent surgery between 2007 and 2015. The mean degree of preoperative curvature was 73.8A degrees (range 60-90A degrees). No intraoperative or major postoperative complications were reported. After a mean follow-up of 33.0 months (range 10-59), complete straightening of the penis was achieved in 74.4%. 88.4% of all patients were able to achieve satisfying sexual intercourse (67.4% unaided, 21.0% with assistance). The IIEF-5 score was improved in 69.8% (mean improvement 4.0 points). Overall 86.0% were satisfied with the surgical treatment. Conclusion Corporoplasty with SIS in patients with PD and severe penile curvature is a safe approach and shows good long-term results. A thorough patient selection and a standardized pre-, intra- and postoperative procedure are decisive for a satisfying outcome.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SURGICAL-MANAGEMENT; PERICARDIAL GRAFT; TUNICA ALBUGINEA; FOLLOW-UP; SATISFACTION; SURGERY; PLAQUE; INCISION; OUTCOMES; PATCH; Peyronie's disease; Induratio penis plastica; Penile curvature; SIS; Small intestinal submucosa |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Urologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Dec 2018 13:16 |
| Last Modified: | 19 Feb 2019 06:53 |
| URI: | https://pred.uni-regensburg.de/id/eprint/1635 |
Actions (login required)
 |
View Item |
