Obesity and Its Impact on Transplantation and Alloimmunity

Heinbokel, Timm and Floerchinger, Bernhard and Schmiderer, Andreas and Edtinger, Karoline and Liu, Guangxiang and Elkhal, Abdallah and Tullius, Stefan G. (2013) Obesity and Its Impact on Transplantation and Alloimmunity. TRANSPLANTATION, 96 (1). pp. 10-16. ISSN 0041-1337, 1534-6080

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Abstract

Obesity has become an increasing problem in healthcare worldwide with far-reaching consequences. More obese patients with irreversible end-stage organ failure undergo organ transplantation, and organs from obese donors are more frequently used. A growing body of evidence suggests more frequent postoperative complications and inferior patient and graft survival linked to obesity. More recently, adipose tissue has been linked to chronic inflammatory processes potentially impacting alloimmune responses and graft quality.

Item Type: Article
Uncontrolled Keywords: BODY-MASS INDEX; ENDOPLASMIC-RETICULUM STRESS; GASTRIC BYPASS-SURGERY; CELL IMMUNE-RESPONSE; STAGE RENAL-DISEASE; KIDNEY-TRANSPLANT; INSULIN-RESISTANCE; LIVER-TRANSPLANTATION; ADIPOSE-TISSUE; RISK-FACTOR; Obesity; Transplantation outcome; Alloimmunity
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 06 Apr 2020 08:38
Last Modified: 06 Apr 2020 08:38
URI: https://pred.uni-regensburg.de/id/eprint/16365

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